Effect of baclofen on cocaine self-administration in rats reinforced under fixed-ratio 1 and progressive-ratio schedules

Drugs of abuse: anatomy, pharmacology and function of reward pathways

1992 • 2,091 citations

Progressive ratio schedules in drug self-administration studies in rats: a method to evaluate reinforcing efficacy

1996 • 1,301 citations

Extinction and recovery of cocaine self-administration following 6-hydroxydopamine lesions of the nucleus accumbens

1980 • 736 citations

On the role of ascending catecholaminergic systems in intravenous self-administration of cocaine

1977 • 733 citations

Increased Lever Pressing for Amphetamine After Pimozide in Rats: Implications for a Dopamine Theory of Reward

1975 • 536 citations

Blockade of cocaine reinforcement in rats with the dopamine receptor blocker pimozide, but not with the noradrenergic blockers phentolamine or phenoxybenzamine.

1977 • 490 citations

The estrous cycle affects cocaine self-administration on a progressive ratio schedule in rats

1989 • 369 citations

Glutamate decarboxylase immunoreactive neurons in rat neostriatum: their morphological types and populations

1988 • 365 citations

Neurobiology of cocaine abuse

1992 • 350 citations

Regulation of somatodendritic dopamine release in the ventral tegmental area by opioids and GABA: an in vivo microdialysis study

1992 • 311 citations

Effects of dopamine D-1 and D-2 antagonists on cocaine self-administration under different schedules of reinforcement in the rat.

1994 • 299 citations

Fluoxetine reduces intravenous cocaine self-administration in rats

1990 • 254 citations

A concurrently available nondrug reinforcer prevents the acquisition or decreases the maintenance of cocaine-reinforced behavior

1989 • 240 citations

Self-administration of cocaine on a progressive ratio schedule in rats: dose-response relationship and effect of haloperidol pretreatment

1989 • 240 citations

D1 receptors modulate glutamate transmission in the ventral tegmental area

1995 • 235 citations

Break-points on a progressive ratio schedule reinforced by intravenous cocaine increase following depletion of forebrain serotonin

1990 • 231 citations

A Common Mechanism Mediates Long-Term Changes in Synaptic Transmission after Chronic Cocaine and Morphine

1996 • 224 citations

Behavioral economics of drug self-administration. I. Functional equivalence of response requirement and drug dose

1990 • 224 citations

Dopaminergic antagonism within the nucleus accumbens or the amygdala produces differential effects on intravenous cocaine self-administration under fixed and progressive ratio schedules of reinforcement

1993 • 214 citations

A novel strategy for the treatment of cocaine addiction

1998 • 196 citations

Baclofen Attenuates the Reinforcing Effects of Cocaine in Rats

1996 • 196 citations

Cocaine inhibits GABA release in the VTA through endogenous 5-HT

1994 • 191 citations

Effects of selective D1 and D2 dopamine antagonists on cocaine self-administration in the rat

1991 • 172 citations

Effects of baclofen on maintenance and reinstatement of intravenous cocaine self-administration in rats

1999 • 155 citations

Baclofen suppression of cocaine self-administration: demonstration using a discrete trials procedure

1997 • 150 citations

The GABAB agonist baclofen modifies cocaine self-administration in rats.

1998 • 139 citations

Food deprivation and acquisition of intravenous cocaine self-administration in rats: effect of naltrexone and haloperidol.

1989 • 134 citations

Intravenous cocaine self-administration in rats is reduced by dietaryl-tryptophan

1990 • 125 citations

GABAergic attenuation of cocaine-induced dopamine release and locomotor activity

1997 • 116 citations

Single-dose bromocriptine reverses cocaine craving

1987 • 111 citations

A topographically organized gamma‐aminobutyric acid projection from the ventral pallidum to the nucleus accumbens in the rat

1994 • 111 citations

Continuous cocaine administration produces persisting changes in brain neurochemistry and behavior

1991 • 91 citations

Effects of alprazolam on intravenous cocaine self-administration in rats

1993 • 66 citations

Chlordiazepoxide alters intravenous cocaine self-administration in rats

1989 • 65 citations

New Pharmacotherapies for Cocaine Dependence... Revisited

1992 • 61 citations

Drug Self-Administration: Experimental Methods and Determinants

2003 • 59 citations

Chronic cocaine enhances gamma-aminobutyric acid and glutamate release by altering presynaptic and not postsynaptic gamma-aminobutyric acidB receptors within the rat dorsolateral septal nucleus.

1997 • 57 citations

Food deprivation affects extinction and reinstatement of responding in rats

1995 • 56 citations

Stereospecific actions of baclofen on sociosexual behavior, locomotor activity and motor execution

1989 • 56 citations

A single injection of either flupenthixol decanoate or haloperidol decanoate produces long-term changes in cocaine self-administration in rats

1994 • 51 citations

Double-blind evaluation of the effect of acute amantadine on cocaine craving

1989 • 45 citations

In vivo release of dopamine from rat striatum, substantia nigra and prefrontal cortex: differential modulation by baclofen

1993 • 43 citations

Behavioral and neurochemical changes caused by repeated ethanol and cocaine administration

1993 • 41 citations

Repeated cocaine injections decrease the function of striatal gamma-aminobutyric acid(A) receptors.

1996 • 40 citations

Pharmacotherapy, Current and Potential, for the Treatment of Cocaine Dependence

1995 • 39 citations

Food deprivation and stimulant self-administration in rats: differences between cocaine and d-amphetamine

1987 • 37 citations

Interpretation of Lesion Effects on Stimulant Self-Administration

1987 • 34 citations

Effect of Dopaminergic Drugs on Cocaine Reinforcement

1995 • 30 citations

Differential effects of chronic antidepressants in behavioural tests of β-adrenergic and GABAB receptor function

1991 • 29 citations

Pentobarbital-like discriminative stimulus effects of direct GABA agonists in rats

1993 • 26 citations

Effects of carbamazepine on self-administration of intravenously delivered cocaine in rats

1990 • 20 citations

Food intake suppressant effect of baclofen in rats

1989 • 19 citations