(S)-(+)-4-[7-(2,2-Dimethyl-1-oxopro- poxy)-4-methyl-2-[4-[2-(1-piperidinyl)- ethoxy]phenyl]-2H-1-benzopyran-3-yl]- phenyl 2,2-Dimethylpropanoate (EM-800): A Highly Potent, Specific, and Orally Active Nonsteroidal Antiestrogen

Cancer statistics, 1997

1997 • 2,045 citations

Establishment and characterization of a cell line of human breast carcinoma origin

1979 • 653 citations

Estrogenic Regulation of Growth and Polypeptide Growth Factor Secretion in Human Breast Carcinoma

1987 • 576 citations

Adjuvant Tamoxifen Therapy for Early Stage Breast Cancer and Second Primary Malignancies

1995 • 515 citations

Tamoxifen in advanced breast cancer

1978 • 343 citations

Tourette Syndrome: Prediction of Phenotypic Variation in Monozygotic Twins by Caudate Nucleus D2 Receptor Binding

1996 • 250 citations

ICI 182,780, a new antioestrogen with clinical potential

1992 • 240 citations

Biology and mode of action of pure antioestrogens.

1988 • 149 citations

Descriptive Clinicopathologic Study of 17 Patients With Endometrial Cancer During or After Adjuvant Tamoxifen in Early Breast Cancer

1993 • 147 citations

Biology and mode of action of pure antioestrogens

1988 • 136 citations

The future of new pure antiestrogens in clinical breast cancer

1993 • 133 citations

Regulation of Progesterone-Binding Breast Cyst Protein GCDFP-24 Secretion by Estrogens and Androgens in Human Breast Cancer Cells: A New Marker of Steroid Action in Breast Cancer*

1990 • 113 citations

The estrogenic and antiestrogenic activities of androgens in female target tissues

1983 • 105 citations

Synthesis and biological activity of new halo-steroidal antiestrogens

1991 • 82 citations

Synthetic antiestrogens modulate induction of pS2 and cathepsin-D messenger ribonucleic acid by growth factors and adenosine 3',5'-monophosphate in MCF7 cells.

1993 • 81 citations

Structure-activity relationship of antiestrogens. Studies on 2,3-diaryl-1-benzopyrans

1990 • 49 citations

Structure-activity relationship of antiestrogens. Effect of the side chain and its position on activity of 2,3-diaryl-2H-1-benzopyrans

1990 • 48 citations

Synthesis and anthelmintic activity of 3'-benzoylurea derivatives of 6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole

1991 • 44 citations

Regulation of pS2 Gene Expression by Affinity Labeling and Reversibly Binding Estrogens and Antiestrogens: Comparison of Effects on the Native Gene and on pS2-Chloramphenicol Acetyltransferase Fusion Genes Transfected into MCF-7 Human Breast Cancer Cells

1988 • 44 citations

Structure-activity relationship of antiestrogens. Phenolic analogs of 2,3-diaryl-2H-1-benzopyrans

1990 • 38 citations

Biological responses of ICI 164,384 and other anti-estrogens in vaginal and uterine cells of fetal guinea pig in culture

1991 • 10 citations

Studies on the activation of the oestrogen receptor bound to the anti-oestrogens 4-hydroxytamoxifen and ICI 164,384 by using three monoclonal antibodies

1991 • 7 citations