Synthetic antiestrogens modulate induction of pS2 and cathepsin-D messenger ribonucleic acid by growth factors and adenosine 3',5'-monophosphate in MCF7 cells.

A Human Cell Line From a Pleural Effusion Derived From a Breast Carcinoma 2

1973 • 2,431 citations

Phenol red in tissue culture media is a weak estrogen: implications concerning the study of estrogen-responsive cells in culture.

1986 • 1,282 citations

The pharmacology and clinical uses of tamoxifen

1984 • 873 citations

Role of the two activating domains of the oestrogen receptor in the cell-type and promoter-context dependent agonistic activity of the anti-oestrogen 4-hydroxytamoxifen.

1990 • 772 citations

Cloning of cDNA sequences of hormone-regulated genes from the MCF-7 human breast cancer cell line

1982 • 727 citations

Steroid hormone receptors compete for factors that mediate their enhancer function

1989 • 580 citations

Coupling of dual signaling pathways: epidermal growth factor action involves the estrogen receptor.

1992 • 486 citations

Post-transcriptional regulation of glyceraldehyde-3-phosphate-dehydrogenase gene expression in rat tissues

1984 • 486 citations

Estrogen Control of Progesterone Receptor in Human Breast Cancer: Role of Estradiol and Antiestrogen*

1978 • 407 citations

Tamoxifen and metabolites in MCF7 cells: correlation between binding to estrogen receptor and inhibition of cell growth.

1982 • 393 citations

[Establishment of a new human endometrial adenocarcinoma cell line, Ishikawa cells, containing estrogen and progesterone receptors].

1985 • 344 citations

Identification of an estrogen response element upstream of the human c-fosgene that binds the estrogen receptor and the AP-1 transcription factor

1990 • 296 citations

The 5′ flanking region of the pS2 gene contains a complex enhancer region responsive to oestrogens, epidermal growth factor, a tumour promoter (TPA), the c-Ha-ras oncoprotein and the c-jun protein.

1989 • 260 citations

Estrogen and Antiestrogen Action in Reproductive Tissues and Tumors

1979 • 194 citations

Multihormonal Regulation of the Progesterone Receptor in MCF-7 Human Breast Cancer Cells: Interrelationships among Insulin/Insulin-Like Growth Factor-I, Serum, and Estrogen*

1990 • 187 citations

Regulation of Cathepsin-D and pS2 Gene Expression by Growth Factors in MCF7 Human Breast Cancer Cells

1989 • 180 citations

Antiestrogenic Effect of R5020, a Synthetic Progestin in Human Breast Cancer Cells in Culture*

1983 • 173 citations

Effects of antiestrogens on the estrogen-regulated pS2 RNA and the 52- and 160-kilodalton proteins in MCF7 cells and two tamoxifen-resistant sublines.

1984 • 120 citations

Mechanisms of 4-hydroxytamoxifen anti-growth factor activity in breast cancer cells: Alterations of growth factor receptor binding sites and tyrosine kinase activity

1990 • 65 citations

Anti-steroidal and anti-growth factor activities of anti-estrogens

1990 • 52 citations

Differential regulation of cathepsin D by sex steroids in mammary cancer and uterine cells

1989 • 46 citations

Cloning of cDNA sequences of a progestin-regulated mRNA from MCF7 human breast cancer cells

1986 • 36 citations

Enzymatic determination of estradiol and estrone in plasma and urine

1979 • 33 citations

Tamoxifen treatment increases the concentration of 52K-cathepsin D and its precursor in breast cancer tissue

1989 • 25 citations

The Role of Intracellular Equilibria and the Effect of Antiestrogens on Estrogen-Receptor Dissociation Kinetics from Perfused Cultures of Human Breast Cancer Cells*

1980 • 18 citations