The Role of Actin-binding Protein 280 in Integrin-dependent Mechanoprotection

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

Mechanotransduction Across the Cell Surface and Through the Cytoskeleton

1993 • 2,947 citations

The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C

1991 • 2,499 citations

Calcium signaling

1995 • 1,905 citations

Extracellular Matrix Rigidity Causes Strengthening of Integrin–Cytoskeleton Linkages

1997 • 1,218 citations

Actin-Binding Protein Requirement for Cortical Stability and Efficient Locomotion

1992 • 567 citations

Human endothelial actin-binding protein (ABP-280, nonmuscle filamin): a molecular leaf spring.

1990 • 522 citations

Mechanism of endothelial cell shape change and cytoskeletal remodeling in response to fluid shear stress

1996 • 503 citations

Loss, Restoration, and Maintenance of Plasma Membrane Integrity

1997 • 341 citations

Actin-binding proteins

1991 • 289 citations

Interactions of actin, myosin, and a new actin-binding protein of rabbit pulmonary macrophages. II. Role in cytoplasmic movement and phagocytosis.

1976 • 289 citations

Quantitative video microscopy of patch clamped membranes stress, strain, capacitance, and stretch channel activation

1991 • 258 citations

Mechanical transduction in biological systems.

1988 • 255 citations

Direct interaction of filamin (ABP-280) with the beta 2-integrin subunit CD18.

1995 • 252 citations

Signal transduction and the actin cytoskeleton: the roles of MARCKS and profilin

1992 • 203 citations

Calcium ions and tyrosine phosphorylation interact coordinately with actin to regulate cytoprotective responses to stretching

1997 • 200 citations

Rapid Induction and Isolation of Focal Adhesion Complexes

1993 • 174 citations

On the association of glycoprotein Ib and actin-binding protein in human platelets.

1985 • 165 citations

The gelation of actin by actin-binding protein.

1978 • 155 citations

Magnetic fields applied to collagen-coated ferric oxide beads induce stretch-activated Ca2+ flux in fibroblasts

1995 • 154 citations

Quantitation of actin polymerization in two human fibroblast sub-types responding to mechanical stretching

1991 • 149 citations

Role of integrins in regulation of collagen phagocytosis by human fibroblasts

1996 • 143 citations

Actin-binding protein contributes to cell volume regulatory ion channel activation in melanoma cells.

1993 • 142 citations

Purification and properties of filamin, and actin binding protein from chicken gizzard.

1976 • 141 citations

TNF-alpha inactivation of collagen receptors: implications for fibroblast function and fibrosis.

1996 • 125 citations

Role of the actin cytoskeleton on epithelial Na+ channel regulation

1995 • 114 citations

Modulation of contraction by gelation/solation in a reconstituted motile model.

1991 • 112 citations

A Three-dimensional Collagen Lattice Induces Protein Kinase C-ζ Activity: Role in α2 Integrin and Collagenase mRNA Expression

1997 • 96 citations

Cellular and molecular adaptations to injurious mechanical stress

1993 • 84 citations

Deficiencies in collagen phagocytosis by human fibroblasts in vitro: A mechanism for fibrosis?

1993 • 84 citations

Mechanism of collagen phagocytosis by human gingival fibroblasts: importance of collagen structure in cell recognition and internalization

1991 • 83 citations

Slow oscillations of free intracellular calcium ion concentration in human fibroblasts responding to mechanical stretch

1994 • 79 citations

Cell-substrate interactions and locomotion of Dictyostelium wild-type and mutants defective in three cytoskeletal proteins: a study using quantitative reflection interference contrast microscopy

1995 • 79 citations

Reconstitution and regulation of actin gel-sol transformation with purified filamin and villin.

1981 • 73 citations

Thrombin-induced GPIb-IX centralization on the platelet surface requires actin assembly and myosin II activation

1996 • 71 citations

Actin Filament Crosslinking by Chicken Gizzard Filamin Is Regulated by Phosphorylation in Vitro

1995 • 69 citations

Regulation of Src Homology 2-containing Tyrosine Phosphatase 1 during Activation of Human Neutrophils

1997 • 69 citations

A new method for application of force to cells via ferric oxide beads

1997 • 61 citations

Mechanochemical proteins, cell motility and cell‐cell contacts: The localization of mechanochemical proteins inside cultured cells at the edge of an in vitro “wound”

1979 • 56 citations

Identification of a filamin isoform enriched at the ends of stress fibers in chicken embryo fibroblasts

1989 • 52 citations

Actin‐binding proteins regulate the work performed by myosin II motors on single actin filaments

1992 • 49 citations

Novel actin crosslinker superfamily member identified by a two step degenerate PCR procedure

1995 • 46 citations

The influence of cations on the polymerization of actin and actin in the presence of α-actinin/filamin

1995 • 5 citations