Caspase involved synergistic cytotoxicity of bcl-2 antisense oligonucleotides and Adriamycin on transitional cell cancer cells

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

1983 • 52,849 citations

Ordering the Cytochrome c–initiated Caspase Cascade: Hierarchical Activation of Caspases-2, -3, -6, -7, -8, and -10 in a Caspase-9–dependent Manner

1999 • 1,927 citations

Caspase Cleavage of Keratin 18 and Reorganization of Intermediate Filaments during Epithelial Cell Apoptosis

1997 • 596 citations

BCL-2 antisense therapy in patients with non-Hodgkin lymphoma

1997 • 502 citations

Smith's General Urology

1996 • 338 citations

Smith's General Urology

2003 • 338 citations

Induction of Apoptosis in Small-Cell Lung Cancer Cells by an Antisense Oligodeoxynucleotide Targeting the Bcl-2 Coding Sequence

1997 • 221 citations

Diagnosis and Management of Genitourinary Cancer

1988 • 208 citations

Synergistic cytotoxicity of bcl-2 antisense oligodeoxynucleotides and etoposide, doxorubicin and cisplatin on small-cell lung cancer cell lines

1998 • 145 citations

Combination chemotherapy in vitro with adriamycin. Observations of additive, antagonistic, and synergistic effects when used in two-drug combinations on cultured human lymphoma cells.

1976 • 120 citations

Protease activation and cleavage of poly(ADP-ribose) polymerase: an integral part of apoptosis in response to photodynamic treatment.

1998 • 107 citations

Investigations of Antisense Oligonucleotides Targeted Againstbcl-2RNAs

1993 • 95 citations

A randomized trial comparing methotrexate and vinblastine (MV) with cisplatin, methotrexate and vinblastine (CMV) in advanced transitional cell carcinoma: results and a report on prognostic factors in a Medical Research Council study

1998 • 92 citations

Bcl-2 overexpression results in reciprocal downregulation of Bcl-XL and sensitizes human testicular germ cell tumours to chemotherapy-induced apoptosis

1999 • 79 citations

Activation of actin-cleavable interleukin 1beta-converting enzyme (ICE) family protease CPP-32 during chemotherapeutic agent-induced apoptosis in ovarian carcinoma cells.

1996 • 72 citations

Abrogation of apoptosis induced by DNA-damaging agents in human bladder-cancer cell lines withp21/WAF1/CIP1 and/orp53 gene alterations

1996 • 58 citations

mRNA and protein expression of p53 mutations in human bladder cancer cell lines

1994 • 27 citations

Bcl-x and the regulation of survival in the immune system

1997 • 26 citations

CORRELATION OF p53 PROTEIN EXPRESSION IN HUMAN UROTHELIAL TRANSITIONAL CELL CANCERS WITH MALIGNANT POTENTIAL AND PATIENT SURVIVAL

1994 • 26 citations

Tetrapeptide DEVD-aldehyde or YVAD-chloromethylketone inhibits Fas/Apo-1 (CD95)-mediated apoptosis in renal-cell-cancer cells

1996 • 26 citations

Pharmacodynamics of doxorubicin in human bladder tumors.

1996 • 23 citations

Activation and role of caspases in chemotherapy-induced apoptosis

1999 • 23 citations

Variable Bcl-2 phenotype in benign and malignant lesions of urothelium

1998 • 18 citations

Intra-Arterial Chemotherapy of Infiltrative Bladder Carcinoma

1985 • 14 citations

Adriamycin (ADM) induced apoptosis in Transitional Cell Cancer (TCC) cell lines accompanied by p21 WAF1/CIP1 induction

1997 • 10 citations

Neoadjuvant CMV Chemotherapy plus Radical Cystectomy in Locally Advanced Bladder Cancer: The Impact of Pathologic Response on Long-Term Results

1996 • 9 citations