Pharmacodynamics of doxorubicin in human bladder tumors.

p53 Status and the Efficacy of Cancer Therapy in Vivo

1994 • 1,483 citations

Accumulation of Nuclear p53 and Tumor Progression in Bladder Cancer

1994 • 828 citations

Nuclear Overexpression of p53 Protein in Transitional Cell Bladder Carcinoma: A Marker for Disease Progression

1993 • 544 citations

Comparison of the Akaike Information Criterion, the Schwarz criterion and the F test as guides to model selection

1994 • 294 citations

Bcl-2 inhibits chemotherapy-induced apoptosis in neuroblastoma.

1994 • 280 citations

Over‐expression of p53 nuclear oncoprotein in transitional‐cell bladder cancer and its prognostic value

1993 • 264 citations

Protooncogene bcl-2 gene transfer abrogates Fas/APO-1 antibody-mediated apoptosis of human malignant glioma cells and confers resistance to chemotherapeutic drugs and therapeutic irradiation.

1995 • 258 citations

Clinical applications of the histoculture drug response assay.

1995 • 210 citations

Reversal of Chemoresistance of Lymphoma Cells by Antisense-Mediated Reduction ofbcl-2 Gene Expression

1994 • 190 citations

Regulation of chemoresistance by the bcl-2 oncoprotein in non-Hodgkin's lymphoma and lymphocytic leukemia cell lines

1994 • 153 citations

Potential of the histoculture drug-response assay to contribute to cancer patient survival.

1995 • 142 citations

In vivo-like drug responses of human tumors growing in three-dimensional gel-supported primary culture.

1987 • 140 citations

Apoptosis and cancer chemotherapy

1994 • 109 citations

p53 Mutations and Prognosis in Bladder Tumors

1995 • 99 citations

Pharmacokinetics of intravesical mitomycin C in superficial bladder cancer patients.

1991 • 99 citations

p53 immunohistochemistry in transitional cell carcinoma and dysplasia of the urinary bladder correlates with disease progression

1993 • 94 citations

Penetration of mitomycin C in human bladder.

1993 • 94 citations

Molecular Genetic Alterations of Chromosome 17 and p53 Nuclear Overexpression in Human Bladder Cancer

1993 • 94 citations

High-risk human papillomavirus infections and overexpression of p53 protein as prognostic indicators in transitional cell carcinoma of the urinary bladder.

1993 • 90 citations

Use of pharmacologic data and computer simulations to design an efficacy trial of intravesical mitomycin C therapy for superficial bladder cancer

1993 • 84 citations

Pharmacodynamics of mitomycin C in cultured human bladder tumors.

1991 • 83 citations

Pharmacodynamics of taxol in human head and neck tumors.

1996 • 65 citations

Up-regulation of a mutant form of p53 by doxorubicin in human squamous carcinoma cells.

1994 • 55 citations

Sponge-Gel-Supported Histoculture Drug-Response Assay for Head and Neck Cancer: Correlations With Clinical Response to Cisplatin

1994 • 53 citations

P-glycoprotein expression in primary and metastatic transitional cell carcinoma of the bladder

1994 • 53 citations

Changes in biological markers after primary chemotherapy for breast cancers

1995 • 50 citations

Establishment and Characterization of Doxorubicin-Resistant Human Bladder Cancer Cell Line, Kk47/adm

1992 • 46 citations

Penetration of intravesical doxorubicin in human bladders

1996 • 45 citations

Flow Cytometric Determination of the Multidrug Resistant Phenotype in Transitional Cell Cancer of the Bladder: Implications and Applications

1991 • 38 citations

p53 Gene Mutation in Recurrent Superficial Bladder Cancer

1995 • 37 citations

Intravesical Therapy

1987 • 36 citations

Pharmacokinetics of Intravesical Doxorubicin in Superficial Bladder Cancer Patients

1994 • 36 citations

P-Glycoprotein Expression in Bladder Cancer

1994 • 30 citations

Evaluation of Multiple Drug Resistance in Human Bladder Cancer Cell Lines

1993 • 29 citations

Correlation between the Expression of P-Glycoprotein and Multidrug-Resistant Phenotype in Transitional Cell Carcinoma of the Urinary Tract

1992 • 25 citations

Correlation of Human Bladder Tumor Histoculture Proliferation and Sensitivity to Mitomycin C with Tumor Pathobiology

1994 • 21 citations

Effects of DNA damaging agents on gene expression in two human cancer cell lines.

1993 • 7 citations

Establishment and characterization of a multidrug-resistant human bladder carcinoma cell line RT112/D21

1995 • 7 citations