Separation of multiple genes controlling the T-cell proliferative response to IL-2 and anti-CD3 using recombinant congenic strains

A rapid method for the isolation of functional thymus‐derived murine lymphocytes

1973 • 4,203 citations

T Cell Growth Factor: Parameters of Production and a Quantitative Microassay for Activity

1978 • 3,314 citations

Xenogeneic Monoclonal Antibodies to Mouse Lymphoid Differentiation Antigens*

1979 • 1,989 citations

CTLA-4 is a second receptor for the B cell activation antigen B7.

1991 • 1,662 citations

"Panning" for lymphocytes: a method for cell selection.

1978 • 1,319 citations

Costimulation of T lymphocytes: the role of CD28, CTLA-4, and B7/BB1 in interleukin-2 production and immunotherapy

1992 • 1,290 citations

Binding of the B cell activation antigen B7 to CD28 costimulates T cell proliferation and interleukin 2 mRNA accumulation.

1991 • 1,132 citations

Effects of IL-13 on phenotype, cytokine production, and cytotoxic function of human monocytes. Comparison with IL-4 and modulation by IFN-gamma or IL-10.

1993 • 657 citations

Cytokine Receptors and Signal Transduction

1992 • 607 citations

The IL-2 Receptor Complex: Its Structure, Function, and Target Genes

1993 • 601 citations

Transmission of Signals from the T Lymphocyte Antigen Receptor to the Genes Responsible for Cell Proliferation and Immune Function: The Missing Link

1990 • 517 citations

Genetic analysis of autoimmune type 1 diabetes mellitus in mice

1991 • 494 citations

The T cell receptor/CD3 complex is composed of at least two autonomous transduction modules

1992 • 438 citations

Polymorphism in mitogenic effect of IgG1 monoclonal antibodies against T3 antigen on human T cells

1983 • 333 citations

A rat anti-mouse T4 monoclonal antibody (H129.19) inhibits the proliferation of Ia-reactive T cell clones and delineates two phenotypically distinct (T4+, Lyt-2,3-, and T4-, Lyt-2,3+) subsets among anti-Ia cytolytic T cell clones.

1984 • 308 citations

Molecules involved in T-cell costimulation

1993 • 237 citations

Evidence implicating utilization of different T cell receptor-associated signaling pathways by TH1 and TH2 clones.

1990 • 218 citations

A rat antibody against a structure functionally related to the mouse T-cell receptor/T3 complex

1988 • 205 citations

High and low affinity IL 2 receptors: analysis by IL 2 dissociation rate and reactivity with monoclonal anti-receptor antibody PC61.

1985 • 203 citations

Recombinant congenic strains ? A new tool for analyzing genetic traits determined by more than one gene

1986 • 197 citations

Autoimmune syndromes in major histocompatibility complex (MHC) congenic strains of nonobese diabetic (NOD) mice. The NOD MHC is dominant for insulitis and cyclophosphamide-induced diabetes.

1992 • 178 citations

Genetic control of host resistance to infection and malignancy

1987 • 148 citations

The regulation and function of p21ras in T cells

1992 • 98 citations

The recombinant congenic strains for analysis of multigenic traits: genetic composition

1992 • 88 citations

The recombinant congenic strains—a novel genetic tool applied to the study of colon tumor development in the mouse

1991 • 67 citations

Differential activation of antigen-stimulated suicide and cytokine production pathways in CD4+ T cells is regulated by the antigen-presenting cell.

1993 • 62 citations

MAPPING OF GENES CONTROLLING LEISHMANIA MAJOR INFECTION IN CXS RECOMBINANT INBRED MICE

1993 • 58 citations

Scc-1, a novel colon cancer susceptibility gene in the mouse: linkage to CD44 (Ly-24, Pgp-1) on chromosome 2.

1992 • 54 citations

Superantigen-driven peripheral deletion of T cells. Apoptosis occurs in cells that have lost the alpha/beta T cell receptor.

1993 • 52 citations

The mouse Ly-17 locus identifies a polymorphism of the Fc receptor

1985 • 50 citations

Genetic resolution of susceptibility to cancer--new perspectives.

1992 • 40 citations

Genetics of Tumor Susceptibility in the Mouse: Mhc and Non-Mhc Genes

1989 • 35 citations

Genetic dissection of susceptibility to radiation-induced apoptosis of thymocytes and mapping of Rapop1, a novel susceptibility gene

1995 • 34 citations

Kras-2 alleles, mutations, and lung tumor susceptibility in the mouse--an evaluation.

1994 • 23 citations

Regulatory role of CD4/L3T4 molecules in IL-2 production by affecting intracellular Ca2+ concentration of T cell clone stimulated with soluble anti-CD3.

1990 • 14 citations

Differential myelopoietic responsiveness of BALB/c (Itys) and C.D2 (Ityr) mice to lipopolysaccharide administration and Salmonella typhimurium infection

1992 • 12 citations

Activation of T lymphocytes through the Ly-6 pathway is defective in A strain mice.

1989 • 10 citations

Exogenous interleukin-2 abrogates differences in the proliferative responses to T cell mitogens among inbred strains of mice

1992 • 9 citations

Establishment and characterization of a permanent T-cell line producing an antigen non-specific suppressor factor.

1985 • 7 citations