Purification of phosphoinositide‐specific phospholipase C from a particulate fraction of bovine brain

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Inositol trisphosphate, a novel second messenger in cellular signal transduction

1984 • 6,088 citations

Release of Ca2+ from a nonmitochondrial intracellular store in pancreatic acinar cells by inositol-1,4,5-trisphosphate

1983 • 2,596 citations

[16] Preparation of buffers for use in enzyme studies

1955 • 1,009 citations

Role of guanine nucleotide binding protein in the activation of polyphosphoinositide phosphodiesterase

1985 • 960 citations

Unsaturated diacylglycerol as a possible messenger for the activation of calcium-activated, phospholipid-dependent protein kinase system

1979 • 727 citations

The Metabolism of Phosphoinositide-Derived Messenger Molecules

1986 • 717 citations

Inositol Phospholipid Hydrolysis in Rat Cerebral Cortical Slices: I. Receptor Characterisation

1984 • 517 citations

5-Hydroxytryptamine stimulates inositol phosphate production in a cell-free system from blowfly salivary glands. Evidence for a role of GTP in coupling receptor activation to phosphoinositide breakdown.

1985 • 429 citations

Hormone-stimulated polyphosphoinositide breakdown in rat liver plasma membranes. Roles of guanine nucleotides and calcium.

1986 • 378 citations

Receptor-Coupled Activation of Phosphoinositide-Specific Phospholipase C by an N Protein

1986 • 324 citations

Identification and properties of two distinct phosphatidylinositol-specific phospholipase C enzymes from sheep seminal vesicular glands.

1982 • 248 citations

PHOSPHATIDYLINOSITOL TURNOVER IN RECEPTOR MECHANISM AND SIGNAL TRANSDUCTION

1985 • 207 citations

Characterization of the cholinergic stimulation of phosphoinositide hydrolysis in rat brain slices

1984 • 175 citations

Thyrotropin-releasing hormone and GTP activate inositol trisphosphate formation in membranes isolated from rat pituitary cells.

1986 • 169 citations

A guanine nucleotide-dependent phosphatidylinositol 4,5-diphosphate phospholipase C in cells transformed by the v-fms and v-fes oncogenes.

1986 • 168 citations

Regulation of phosphoinositide breakdown by guanine nucleotides

1986 • 160 citations

Receptor coupled events in bradykinin action: rapid production of inositol phosphates and regulation of cytosolic free Ca2+ in a neural cell line.

1987 • 138 citations

Guanine nucleotides stimulate production of inositol trisphosphate in rat cortical membranes

1985 • 125 citations

Regulation of membrane-associated and cytosolic phospholipase C activities in human platelets by guanosine triphosphate.

1986 • 98 citations

Inositol bis-, tris-, and tetrakis(phosphate)s: analysis in tissues by HPLC.

1986 • 93 citations

Rapid estimation of the molecular weights of protein polypeptide chains using high-pressure liquid chromatography in 6 m guanidine hydrochloride

1979 • 87 citations

‘Phosphatido-peptide’-like complexes formed by the interaction of calcium triphosphoinositide with protein

1965 • 86 citations

Regulation of a liver plasma membrane phosphoinositide phosphodiesterase by guanine nucleotides and calcium

1985 • 83 citations

Characterization of multiple forms of phosphoinositide-specific phospholipase C purified from human platelets

1986 • 78 citations

Two forms of phosphatidylinositol-specific phospholipase C from bovine brain

1986 • 77 citations

Partial purification of phosphoinositide phospholipase C from human platelet cytosol; characterization of its three forms

1986 • 70 citations

Rat brain and liver soluble phospholipase C: Resolution of two forms with different requirements for calcium

1985 • 63 citations

Phospholipase C in rat liver plasma membranes

1986 • 53 citations

Partial Purification and Characterization of Membrane-Bound and Cytosolic Phosphatidylinositol-Specific Phospholipases C from Murine Thymocytes

1986 • 34 citations