NF-I/Sp1 Switch Elements Regulate Collagen α1(I) Gene Expression

Firefly luciferase gene: structure and expression in mammalian cells.

1987 • 3,088 citations

How eukaryotic transcriptional activators work

1988 • 1,924 citations

Analysis of Sp1 in vivo reveals mutiple transcriptional domains, including a novel glutamine-rich activation motif

1988 • 1,403 citations

Mechanism of transcriptional activation by Sp1: Evidence for coactivators

1990 • 1,029 citations

Two distinct transcription factors bind to the HSV thymidine kinase promoter in vitro

1985 • 805 citations

The proline-rich transcriptional activator of CTF/NF-I is distinct from the replication and DNA binding domain

1989 • 781 citations

A family of human CCAAT-box-binding proteins active in transcription and DNA replication: cloning and expression of multiple cDNAs

1988 • 747 citations

Isolation of coactivators associated with the TATA-binding protein that mediate transcriptional activation

1991 • 711 citations

GC box binding induces phosphorylation of Sp1 by a DNA-dependent protein kinase

1990 • 677 citations

Steroid hormone receptors compete for factors that mediate their enhancer function

1989 • 580 citations

Cloning and expression of AP-2, a cell-type-specific transcription factor that activates inducible enhancer elements.

1988 • 578 citations

Multiple specific contacts between a mammalian transcription factor and its cognate promoters

1984 • 565 citations

Synergistic activation by the glutamine-rich domains of human transcription factor Sp1

1989 • 539 citations

Activation of Cell-Specific Expression of Rat Growth Hormone and Prolactin Genes by a Common Transcription Factor

1988 • 525 citations

Jun-Fos and receptors for vitamins A and D recognize a common response element in the human osteocalcin gene

1990 • 522 citations

Negative Regulation by Glucocorticoids Through Interference with a cAMP Responsive Enhancer

1988 • 502 citations

Transcriptional repression of eukaryotic promoters

1989 • 481 citations

Transforming growth factor beta increases mRNA for matrix proteins both in the presence and in the absence of changes in mRNA stability.

1988 • 420 citations

Embryonic lethal mutation in mouse collagen I gene causes rupture of blood vessels and is associated with erythropoietic and mesenchymal cell death

1984 • 285 citations

Developmental expression of Sp1 in the mouse.

1991 • 276 citations

Tumor necrosis factor alpha inhibits collagen gene transcription and collagen synthesis in cultured human fibroblasts.

1988 • 241 citations

Steroid receptor-mediated inhibition of rat prolactin gene expression does not require the receptor DNA-binding domain

1988 • 238 citations

Insertion of retrovirus into the first intron of alpha 1(I) collagen gene to embryonic lethal mutation in mice.

1984 • 229 citations

Transcriptional repression in eukaryotes

1990 • 210 citations

Regulatory elements in the first intron contribute to transcriptional control of the human alpha 1(I) collagen gene.

1987 • 191 citations

Contactpoint analysis of the HeLa nuclear factor I recognition site reveals symmetrical binding at one side of the DNA helix.

1987 • 168 citations

Fine structural analysis of the human pro-alpha 1 (I) collagen gene. Promoter structure, AluI repeats, and polymorphic transcripts.

1985 • 162 citations

A purified Drosophila homeodomain protein represses transcription in vitro

1989 • 142 citations

A Simplified Method for the Preparation of Transcriptionally Active Liver Nuclear Extracts

1990 • 134 citations

Transcription factors nuclear factor I and Sp1 interact with the murine collagen alpha 1 (I) promoter.

1991 • 131 citations

Transcriptional inhibition by a glucocorticoid receptor-β-galactosidase fusion protein

1988 • 129 citations

SV40 stimulates expression of the transacting factor Sp1 at the mRNA level.

1990 • 124 citations

Regulatory elements in the 5'-flanking region and the first intron contribute to transcriptional control of the mouse alpha 1 type I collagen gene.

1989 • 121 citations

Synergistic activation of a human promoter in vivo by transcription factor Sp1.

1991 • 115 citations

Nuclear factor-I and activator protein-2 bind in a mutually exclusive way to overlapping promoter sequences andtrans-activate the human growth hormone gene

1990 • 102 citations

An upstream regulatory region mediates high-level, tissue-specific expression of the human alpha 1(I) collagen gene in transgenic mice.

1991 • 83 citations

Analysis of the collagen α(I) promoter

1989 • 64 citations

Unusual DNA sequences located within the promoter region and the first intron of the chicken pro-alpha 1(I) collagen gene.

1987 • 34 citations

Transcriptional control of the α 1(I) collagen gene involves orientation- and position-specific intronic sequences

1990 • 27 citations

Human-mouse interspecies collagen I heterotrimer is functional during embryonic development of Mov13 mutant mouse embryos.

1990 • 15 citations

Vasopressin Inhibits Type-I Collagen and Albumin Gene Expression in Primary Cultures of Adult Rat Hepatocytes

1989 • 13 citations