SV40 stimulates expression of the transacting factor Sp1 at the mRNA level.

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Genomic sequencing.

1984 • 8,343 citations

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

SV40-transformed simian cells support the replication of early SV40 mutants

1981 • 2,564 citations

Chromosome 17 Deletions and p53 Gene Mutations in Colorectal Carcinomas

1989 • 2,081 citations

Isolation of cDNA encoding transcription factor Sp1 and functional analysis of the DNA binding domain

1987 • 1,640 citations

SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene

1988 • 1,490 citations

Purification and Biochemical Characterization of the Promoter-Specific Transcription Factor, Sp1

1986 • 1,473 citations

The promoter-specific transcription factor Sp1 binds to upstream sequences in the SV40 early promoter

1983 • 1,471 citations

Analysis of Sp1 in vivo reveals mutiple transcriptional domains, including a novel glutamine-rich activation motif

1988 • 1,403 citations

The Rous sarcoma virus long terminal repeat is a strong promoter when introduced into a variety of eukaryotic cells by DNA-mediated transfection.

1982 • 1,371 citations

Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life.

1988 • 1,140 citations

Monoclonal antibodies specific for simian virus 40 tumor antigens

1981 • 1,110 citations

Promoter-specific activation of RNA polymerase II transcription by Sp1

1986 • 1,054 citations

Positive and negative regulation of transcription in vitro: Enhancer-binding protein AP-2 is inhibited by SV40 T antigen

1987 • 969 citations

Isolation of transcription factors that discriminate between different promoters recognized by RNA polymerase II

1983 • 779 citations

Cooperation between gene encoding p53 tumour antigen and ras in cellular transformation

1984 • 761 citations

Participation of p53 cellular tumour antigen in transformation of normal embryonic cells

1984 • 754 citations

Activation of the AIDS Retrovirus Promoter by the Cellular Transcription Factor, Sp1

1986 • 741 citations

Mutation is required to activate the p53 gene for cooperation with the ras oncogene and transformation

1989 • 599 citations

Synergistic activation by the glutamine-rich domains of human transcription factor Sp1

1989 • 539 citations

HMG CoA reductase: A negatively regulated gene with unusual promoter and 5′ untranslated regions

1984 • 523 citations

SV40 large T antigen binds preferentially to an underphosphorylated member of the retinoblastoma susceptibility gene product family

1989 • 508 citations

INFECTION OF HUMAN AND SIMIAN TISSUE CULTURES WITH ROUS SARCOMA VIRUS

1964 • 354 citations

Adenosine deaminase: characterization and expression of a gene with a remarkable promoter.

1985 • 329 citations

Mitochondrial uncoupling protein from mouse brown fat. Molecular cloning, genetic mapping, and mRNA expression.

1985 • 301 citations

Sp1 binds to promoter sequences and activates herpes simplex virus ‘immediate-early’ gene transcription in vitro

1985 • 289 citations

Transcription factor Sp1 recognizes a DNA sequence in the mouse dihydrofolate reductase promoter

1986 • 281 citations

DNA infectivity and the induction of host DNA synthesis with temperature-sensitive mutants of simian virus 40

1975 • 160 citations

Expression of the mouse HPRT gene: Deletional analysis of the promoter region of an X-Chromosome linked housekeeping gene

1986 • 160 citations

Binding of the Sp1 Transcription Factor by the Human Harvey ras 1 Proto-Oncogene Promoter

1986 • 150 citations

Effects of the position of the simian virus 40 enhancer on expression of multiple transcription units in a single plasmid.

1986 • 118 citations

Evidence for transcriptional and post-transcriptional control of the cellular thymidine kinase gene.

1987 • 111 citations

SV40 large tumor antigen can regulate some cellular transcripts in a positive fashion

1982 • 102 citations

Reactivation of silent rRNA genes by simian virus 40 in human-mouse hybrid cells.

1979 • 90 citations

Induction of Cellular Thymidine Kinase Occurs at the mRNA Level

1985 • 88 citations

A Negative Regulatory Element with Properties Similar to Those of Enhancers Is Contained within an Alu Sequence

1989 • 87 citations

Transcription factor Sp1 recognizes promoter sequences from the monkey genome that are simian virus 40 promoter.

1985 • 83 citations

Mouse DNA polymerase gene promoter: fine mapping and involvement of Sp1-like mouse transcription factor in its function

1988 • 52 citations

3 Lytic Cycle of SV40 and Polyoma Virus

1980 • 46 citations

Ultraviolet shadowing nucleic acids on nylon membranes

1989 • 44 citations

Simian virus 40 T antigen alters the binding characteristics of specific simian DNA-binding factors.

1988 • 39 citations

Association of the adenovirus DNA-binding protein with RNA both in vitro and in vivo.

1986 • 39 citations

Simian virus 40 large tumor antigen: a "RNA binding protein"?

1982 • 29 citations

RNA is covalently linked to SV40 large T antigen.

1988 • 15 citations

Complex formation of simian virus 40 large T antigen with cellular protein p53

1986 • 15 citations

Role of the adenovirus 72-kDa DNA binding protein in the rapid decay of early viral mRNA

1988 • 11 citations

Improved transfection of CV-1 and COS 1 cells using reduced serum medium

1986 • 2 citations