Cloning of rat asparagine synthetase and specificity of the amino acid-dependent control of its mRNA content

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Genomic sequencing.

1984 • 8,343 citations

Regulation of the mevalonate pathway

1990 • 5,282 citations

Regulating the fate of mRNA: The control of cellular iron metabolism

1993 • 1,233 citations

Phosphorylation of initiation factor 2α by protein kinase GCN2 mediates gene-specific translational control of GCN4 in yeast

1992 • 768 citations

PCR Technology: Principles and Applications for DNA Amplification

1990 • 512 citations

GCN4 protein, synthesize in vitro, binds HIS3 regulatory sequences: Implications for general control of amino acid biosynthetic genes in yeast

1985 • 496 citations

Mammalian stress response: induction of the glucose-regulated protein family

1992 • 452 citations

Mechanisms of gene regulation in the general control of amino acid biosynthesis in Saccharomyces cerevisiae

1988 • 449 citations

Metallothionein and the Trace Minerals

1990 • 295 citations

Suppression of ribosomal reinitiation at upstream open reading frames in amino acid-starved cells forms the basis for GCN4 translational control.

1991 • 243 citations

ATTENUATION IN AMINO ACID BIOSYNTHETIC OPERONS

1982 • 218 citations

The cross-pathway control gene of Neurospora crassa, cpc-1, encodes a protein similar to GCN4 of yeast and the DNA-binding domain of the oncogene v-jun-encoded protein.

1988 • 172 citations

Effect of amino acid limitation on the expression of 19 genes in rat hepatoma cells

1994 • 140 citations

Gene expression: nutrient control of pre‐ and posttranscriptional events ¹

1992 • 125 citations

Selective Inhibition of Aminoacyl Ribonucleic Acid Synthetases by Aminoalkyl Adenylates^*

1967 • 119 citations

Reversible Inhibition by Histidinol of Protein Synthesis in Human Cells at the Activation of Histidine

1972 • 108 citations

Cis- and trans-acting elements involved in amino acid regulation of asparagine synthetase gene expression.

1993 • 108 citations

Amino acid‐regulated gene expression in eukaryotic cells

1994 • 98 citations

Regulation of asparagine synthetase gene expression by amino acid starvation.

1991 • 92 citations

Isolation of human cDNAs for asparagine synthetase and expression in Jensen rat sarcoma cells.

1987 • 82 citations

Regulation of amino acid transport system L in Chinese hamster ovary cells.

1982 • 59 citations

Cis-inhibition, trans-inhibition, and repression of hepatic amino acid transport mediated by System A. Substrate specificity and other properties.

1986 • 58 citations

Organization and expression of the cell cycle gene, ts11, that encodes asparagine synthetase.

1989 • 50 citations

Molecular cloning of a gene that is necessary for G1 progression in mammalian cells.

1987 • 50 citations

Genetic distinction between sterol-mediated transcriptional and posttranscriptional control of 3-hydroxy-3-methylglutaryl-coenzyme A reductase

1991 • 49 citations

Nutritional regulation and tissue-specific expression of the serine dehydratase gene in rat.

1991 • 48 citations

Asparaginyl-tRNA aminoacylation levels and asparagine synthetase expression in cultured Chinese hamster ovary cells.

1979 • 48 citations

A mammalian temperature-sensitive mutation affecting G1 progression results from a single amino acid substitution in asparagine synthetase

1990 • 41 citations

Mechanism of regulation of ornithine decarboxylase gene expression by asparagine in a variant mouse neuroblastoma cell line.

1992 • 31 citations

Isolation of Human cDNAs for Asparagine Synthetase and Expression in Jensen Rat Sarcoma Cells

1987 • 26 citations

Production of monospecific antibodies to a low-abundance hepatic membrane protein using nitrocellulose immobilized protein as antigen

1987 • 26 citations

Molecular cloning of an amino acid-regulated mRNA (amino acid starvation-induced) in rat hepatoma cells.

1990 • 26 citations

Regulation of Asparagine Synthetase Gene Expression by Amino Acid Starvation

1991 • 24 citations

High-level expression of human asparagine synthetase and production of monoclonal antibodies for enzyme purification

1992 • 22 citations

cis- and trans-Acting Elements Involved in Amino Acid Regulation of Asparagine Synthetase Gene Expression

1993 • 17 citations

Organization and Expression of the Cell Cycle Gene, ts11, That Encodes Asparagine Synthetase

1989 • 15 citations

Immunochemical characterization of rat testicular asparagine synthetase

1992 • 6 citations

Enhanced mRNA Content in Response to Amino Acid Starvation for a 73-kDa Protein of the Inner Mitochondrial Membrane

1993 • 4 citations