Eating disorders and depression: Is there a serotonin connection?

Psychopharmacology: The third generation of progress

1988 • 3,403 citations

Hudson et al.

1977 • 2,560 citations

Psychopharmacology: The Third Generation of Progress.

1988 • 1,973 citations

5-HIAA in the Cerebrospinal Fluid

1976 • 1,430 citations

Brain Serotonin Content: Physiological Regulation by Plasma Neutral Amino Acids

1972 • 1,164 citations

Aggression in humans correlates with cerebrospinal fluid amine metabolites

1979 • 1,126 citations

Serotonergic Studies in Patients With Affective and Personality Disorders

1989 • 1,093 citations

Tryptophan depletion causes a rapid lowering of mood in normal males

1985 • 726 citations

Brain Serotonin Content: Increase Following Ingestion of Carbohydrate Diet

1971 • 721 citations

Serotonin and appetite

1984 • 579 citations

Tritiated Imipramine Binding Sites Are Decreased in Platelets of Untreated Depressed Patients

1980 • 440 citations

Eating and Its Disorders.

1984 • 404 citations

Zur Serotonin-Hypothese der Depression*

1990 • 397 citations

Bulimia treated with imipramine: a placebo-controlled, double-blind study

1983 • 326 citations

Depressed Patients Have Decreased Binding of Tritiated Imipramine to Platelet Serotonin 'Transporter'

1981 • 317 citations

Phenomenologic relationship of eating disorders to major affective disorder

1983 • 314 citations

Serotonergic Function in Depression

1984 • 280 citations

Abnormalities in CNS Monoamine Metabolism in Anorexia Nervosa

1984 • 261 citations

Anorexia Nervosa

1986 • 252 citations

Plasma prolactin changes following fenfluramine in depressed patients compared to controls: An evaluation of central serotonergic responsibility in depression

1984 • 241 citations

Serotonin Uptake in Blood Platelets of Psychiatric Patients

1981 • 235 citations

Eating Disorders

1985 • 227 citations

Platelets as a model for neurones?

1988 • 225 citations

Treating Bulimia With Desipramine

1986 • 213 citations

A controlled study of lifetime prevalence of affective and other psychiatric disorders in bulimic outpatients

1987 • 213 citations

Decreased uptake of 5-hydroxytryptamine in blood platelets from patients with endogenous depression

1979 • 201 citations

Childhood psychopathology and development

1983 • 197 citations

Platelet 5-hydroxytryptamine accumulation in depressive illness

1978 • 196 citations

The relationship between affective disorder and eating disorders: a review of the literature

1986 • 183 citations

Antidepressants and serotonergic neurotransmission: An integrative review

1985 • 181 citations

A Placebo-Controlled, Double-Blind Trial of Amitriptyline in Bulimia

1984 • 181 citations

Serotonin in Major Psychiatric Disorders

1990 • 177 citations

Psychiatric disorders in the first-degree relatives of probands with bulimia nervosa

1989 • 176 citations

Affective Disturbance in Eating Disorders

1985 • 175 citations

Bulimia and Depression

1985 • 168 citations

Differences in brain serotonergic metabolism between nonbulimic and bulimic patients with anorexia nervosa

1984 • 165 citations

Clinical findings in patients with anorexia nervosa and affective illness in their relatives

1984 • 163 citations

Bulimia nervosa: a placebo controlled double‐blind therapeutic trial of mianserin.

1983 • 160 citations

Amitriptyline in the Treatment of Anorexia Nervosa

1985 • 157 citations

Treatment of Bulimia With Phenelzine

1984 • 155 citations

Decreased plasma tryptophan levels in major depression

1989 • 154 citations

Imipramine in the treatment of bulimia: A double-blind controlled study

1987 • 152 citations

Childhood Psychopathology and Development

1984 • 150 citations

A controlled family history study of bulimia

1987 • 138 citations

Major Affective Disorder in Anorexia Nervosa and Bulimia

1987 • 134 citations

Neuro-Psychopharmacology

1978 • 133 citations

Neuroendocrine Responses to Intravenous Tryptophan in Major Depression

1987 • 131 citations

Neuroendocrine and behavioral effects of dietary tryptophan restriction in healthy subjects

1989 • 126 citations

Treatment of Bulimia with Fenfluramine and Desipramine

1988 • 122 citations

Plasma Tryptophan and Five Other Amino Acids in Depressed and Normal Subjects

1981 • 119 citations

CSF 5-HIAA concentrations in anorexia nervosa: reduced values in underweight subjects normalize after weight gain

1988 • 114 citations

Catecholamine Metabolism in Anorexia Nervosa

1978 • 113 citations

Hypothalamic serotonin: pharmacological, biochemical, and behavioral analyses of its feeding-suppressive action.

1988 • 112 citations

Treatment of Bulimia with Desipramine: A Double-Blind Crossover Study

1988 • 107 citations

Normalization of platelet [3H]imipramine binding in depressed patients during remission

1982 • 102 citations

CSF monoamine levels in normal-weight bulimia: evidence for abnormal noradrenergic activity

1990 • 97 citations

Lower 3H-imipramine binding in platelets from untreated depressed patients compared to healthy controls

1985 • 83 citations

Electroconvulsive Shock Therapy and Maximum Binding of Platelet Tritiated Imipramine Binding in Depression

1986 • 75 citations

The Effects of Dieting and Weight Loss on Neuroendocrine Responses to Tryptophan, Clonidine, and Apomorphine in Volunteers

1987 • 73 citations

Bingeing behavior and plasma amino acids: A possible involvement of brain serotonin in bulimia nervosa

1988 • 70 citations

Fluoxetine as a treatment for bulimia nervosa.

1987 • 67 citations

Antidepressant treatment of bulimia: the relationship between bingeing and depressive symptomatology.

1984 • 66 citations

The Psychobiology of Anorexia Nervosa

1984 • 64 citations

Effects of carbohydrate and protein meals on plasma large neutral amino acids, glucose, and insulin plasma levels of anorectic patients

1986 • 63 citations

Therapeutic indications for serotonin-potentiating compounds: A hypothesis

1987 • 62 citations

CSF neurochemistry of women with anorexia nervosa and normal women

1984 • 61 citations

Use of serotonergic agents in the clinical assessment of central serotonin function.

1986 • 61 citations

How are depression and bulimia related?

1989 • 60 citations

Plasma -tryptophan/neutral amino acid ratio and dexamethasone suppression in depression

1984 • 60 citations

High affinity [3H] imipramine binding and serotonin uptake to platelets of adolescent females suffering from anorexia nervosa

1986 • 57 citations

Pathochemical Markers in Major Psychoses

1985 • 48 citations

Platelet [3H]Imipramine binding in psychiatric disorders

1987 • 46 citations

PLASMA-TRYPTOPHAN IN ANOREXIA NERVOSA

1976 • 44 citations

A controlled trial of d-fenfluramine in bulimia nervosa.

1988 • 42 citations

Evidence for diminished brain 5-hydroxytryptamine biosynthesis in obese diabetic and non-diabetic humans

1985 • 40 citations

The Psychobiology of Bulimia Nervosa

1988 • 40 citations

Altered insulin response to a balanced test meal in bulimic patients

1987 • 39 citations

Pattern of onset of bulimic symptoms in anorexia nervosa

1988 • 39 citations

Platelet serotonin uptake in bulimia nervosa

1990 • 37 citations

Short-term prospective study of recovery in bulimia nervosa

1988 • 36 citations

Involvement of serotonin system in bulimia

1988 • 36 citations

The neuroendocrine responses and psychological effects of infusion of L-tryptophan in anorexia nervosa

1989 • 33 citations

Urinary MHPG in anorexia nervosa patients with and without a concomitant major depressive disorder

1984 • 30 citations

Hormone and metabolite plasma levels after oral glucose in bulimia and healthy controls

1988 • 29 citations

Serotonin (5‐HT) uptake by blood platelets in anorexia nervosa

1987 • 21 citations

Nutritional Control of Central Neurotransmitters

1984 • 19 citations

Pharmacologic Treatment of Eating Disorders

1984 • 17 citations

Are anorexia nervosa and bulimia variants of affective disorders?

1987 • 14 citations

Evidence for Altered Serotonin Function in Bulimia and Anorexia Nervosa: Behavioral Implications

1988 • 12 citations

The treatment of anorexia nervosa: do different treatments have different outcomes?

1984 • 12 citations

Cerebrospinal Fluid Amine Metabolite Studies in Depression: Research Update

1985 • 9 citations

Precursor amino acid concentrations in normal weight bulimics and normal controls

1988 • 9 citations

THE SEROTONERGIC NEUROTRANSMITTER SYSTEM IN THE AFFECTIVE DISORDERS – A PRELIMINARY EVALUATION OF THE ANTIDEPRESSANT AND ANTIMANIC EFFECTS OF FENFLURAMINE

1978 • 8 citations