Therapeutic indications for serotonin-potentiating compounds: A hypothesis

5-HIAA in the Cerebrospinal Fluid

1976 • 1,430 citations

Low cerebrospinal fluid 5-hydroxyindoleacetic acid concentration differentiates impulsive from nonimpulsive violent behavior

1983 • 1,290 citations

Psychopharmacology : a generation of progress

1978 • 1,168 citations

Aggression in humans correlates with cerebrospinal fluid amine metabolites

1979 • 1,126 citations

Aggression, suicide, and serotonin: relationships to CSF amine metabolites

1982 • 915 citations

Monoamine Metabolites in CSF and Suicidal Behavior

1981 • 692 citations

Precursor control of neurotransmitter synthesis.

1980 • 646 citations

Handbook of affective disorders

1982 • 611 citations

Clomipramine Treatment of Obsessive-Compulsive Disorder

1980 • 492 citations

Clomipramine and Exposure for Obsessive-Compulsive Rituals: 1

1980 • 421 citations

Obsessive-compulsive disorder and serotonin: Is there a connection?

1985 • 347 citations

Obsessive Compulsive Disorder

2022 • 305 citations

Clomipramine Treatment of Obsessive-Compulsive Disorder

1980 • 292 citations

Homicide, suicide and CSF 5‐HIAA

1985 • 271 citations

5-Hydroxyindoleacetic Acid Levels in the Cerebrospinal Fluid of Depressive Patients treated with Probenecid

1970 • 253 citations

A Behavioral Dimension of Constraint

1986 • 245 citations

The Influence of Ritanserin, a Serotonin Antagonist, in Anxiety Disorders: A Double-blind Placebo-controlled Study versus Lorazepam

1985 • 223 citations

Psychobiology of aggression and violence

1981 • 220 citations

Biological Psychiatry

1986 • 218 citations

CSF 5-hydroxyindoleacetic acid levels in suicidal schizophrenic patients

1984 • 216 citations

Cerebrospinal fluid 5-hydroxyindoleacetic acid and homovanillic acid in psychiatric patients

1969 • 213 citations

5-hydroxyindoleacetic acid (and homovanillic acid) levels in the cerebrospinal fluid after probenecid application in patiens with manic-depressive psychosis

1969 • 189 citations

The treatment of depression in general practice: a comparison of L-tryptophan, amitriptyline, and a combination of L-tryptophan and amitriptyline with placebo

1982 • 176 citations

Effect of Serotonin Uptake Inhibitors in Anxiety Disorders; a Double-blind Comparison of Clomipramine and Fluvoxamine

1987 • 161 citations

dl-5-Hydroxytryptophan-induced changes in central monoamine neurons after peripheral decarboxylase inhibition

1971 • 155 citations

DEPRESSION

1982 • 147 citations

Dopamine metabolism in depressions, psychoses, and Parkinson's disease: the problem of the specificity of biological variables in behaviour disorders

1975 • 140 citations

Amine metabolism in the human brain: Further evaluation of the probenecid test

1971 • 135 citations

Recent developments in 5HT-related pharmacology of animal models of anxiety

1986 • 127 citations

Long-Term Therapy of Myoclonus and Other Neurologic Disorders with L-5-Hydroxytryptophan and Carbidopa

1977 • 127 citations

Selective Antidepressants and Cerebrospinal Fluid

1985 • 117 citations

Effect of a selective serotonin uptake inhibitor in agoraphobia with panic attacks A double‐blind comparison of zimeldine, imipramine and placebo

1986 • 113 citations

Aggressive behaviour and the central serotonergic systems

1983 • 97 citations

L-tryptophan in obsessive-compulsive disorders

1977 • 97 citations

Reflections on experimental and human pathology of aggression

1984 • 95 citations

Rorschach ratings in depressed and suicidal patients with low levels of 5-hydroxyindoleacetic acid in cerebrospinal fluid

1982 • 93 citations

Biological suicide research: Outcome and limitations

1986 • 89 citations

In search of the mode of action of antidepressants 5-HTP/tyrosine mixtures in depressions

1983 • 87 citations

Desipramine Treatment in Normal Subjects

1986 • 82 citations

The Significance of Dopamine for the Mode of Action of Neuroleptics and the Pathogenesis of Schizophrenia

1977 • 75 citations

Clomipramine and Exposure for Compulsive Rituals: II. Plasma Levels, Side Effects and Outcome

1980 • 74 citations

A double–blind study of zimelidine, a serotonin uptake inhibitor, and desipramine, a noradrenaline uptake inhibitor, in endogenous depression

1982 • 71 citations

Zimeldine treatment of obsessive‐compulsive disorder

1984 • 69 citations

Serotoninergic dysfunction in the 47, XYY syndrome.

1980 • 68 citations

Serenics and aggression

1986 • 51 citations

Studies in the mechanism of action of serotonin precursors in depression.

1984 • 45 citations

Treatment of myoclonus with l‐5‐hydroxytryptophan and carbidopa: Clinical, electrophusiological, and biochemical observations

1980 • 38 citations

Reduced metabolism and turnover rates of rat brain dopamine, norepinephrine and serotonin by chronic desipramine and zimelidine treatments

1984 • 38 citations

A pilot study of the effect of the 5‐HT‐uptake inhibitor, zimelidine, on phobic anxiety

1981 • 32 citations

Reduction of norepinephrine turnover by serotonergic drug in man.

1984 • 31 citations

L-5-HYDROXYTRYPTOPHAN AND MOOD

1975 • 31 citations

Intravenous L-5-Hydroxytryptophan in Normal Subjects: An Interdisciplinary Precursor Loading Study

1976 • 29 citations

On the interaction of 5-hydroxytryptophan and 5-hydroxytryptamine with dopamine metabolism in the rat striatum

1978 • 28 citations

The pitfalls of serotonin precursors as challengers in hormonal probes of central serotonin activity.

1986 • 28 citations

Measurement of 5-HIAA levels in ventricular CSF (by LCEC) and in striatum (byin vivo voltammetry) during pharmacological modifications of serotonin metabolism in the rat

1985 • 27 citations

The treatment of phobic anxiety by zimelidine

1981 • 24 citations

Psychopharmacology — A generation of progress

1980 • 20 citations

ANTIDEPRESSANTS TODAY

1984 • 2 citations