Expression of TNF and the Necessity of TNF Receptors in Bleomycin-Induced Lung Injury in Mice

Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection

1993 • 1,719 citations

Mice lacking the tumour necrosis factor receptor 1 are resistant to IMF-mediated toxicity but highly susceptible to infection by Listeria monocytogenes

1993 • 1,267 citations

Induction of apoptosis in mature T cells by tumour necrosis factor

1995 • 1,139 citations

Modifications of a specific assay for hydroxyproline in urine

1967 • 1,091 citations

TNF Receptor-Deficient Mice Reveal Divergent Roles for p55 and p75 in Several Models of Inflammation

1998 • 715 citations

Prostaglandin E2 regulates macrophage-derived tumor necrosis factor gene expression.

1988 • 670 citations

Decreased sensitivity to tumour-necrosis factor but normal T-cell development in TNF receptor-2-deficient mice

1994 • 607 citations

Tumor necrosis factor/cachectin plays a key role in bleomycin-induced pneumopathy and fibrosis.

1989 • 578 citations

Macrophage production of transforming growth factor beta and fibroblast collagen synthesis in chronic pulmonary inflammation.

1989 • 502 citations

KP1: a new monoclonal antibody that detects a monocyte/macrophage associated antigen in routinely processed tissue sections.

1989 • 485 citations

The pathogenesis of bleomycin-induced pulmonary fibrosis in mice.

1974 • 469 citations

Cytokines of the Lung

1990 • 443 citations

Effect of antibody to transforming growth factor beta on bleomycin induced accumulation of lung collagen in mice.

1993 • 402 citations

Lung Cytokine Production in Bleomycin-Induced Pulmonary Fibrosis

1992 • 321 citations

Treatment by human recombinant soluble TNF receptor of pulmonary fibrosis induced by bleomycin or silica in mice

1994 • 287 citations

Bleomycin-Induced Pulmonary Toxicity

1990 • 244 citations

Interleukin 1 receptor antagonist (IL-1ra) prevents or cures pulmonary fibrosis elicited in mice by bleomycin or silica

1993 • 210 citations

Alterations in pulmonary mRNA encoding procollagens, fibronectin and transforming growth factor-beta precede bleomycin-induced pulmonary fibrosis in mice.

1988 • 199 citations

A role for C-C chemokines in fibrotic lung disease

1995 • 196 citations

Regulation of alveolar macrophage transforming growth factor-beta secretion by corticosteroids in bleomycin-induced pulmonary inflammation in the rat.

1993 • 185 citations

The Role of Strain Variation in Murine Bleomycin-lnduced Pulmonary Fibrosis^1,2

1983 • 183 citations

The Effects of the Nude(nu/nu)Mutation on Bleomycin-induced Pulmonary Fibrosis

1983 • 145 citations

Morphometric estimates of infiltrative cellular changes during the development of bleomycin-induced pulmonary fibrosis in hamsters.

1983 • 144 citations

High dose continuous infusion of bleomycin in mice: a new model for drug-induced pulmonary fibrosis.

1987 • 141 citations

Expression of Transforming Growth Factor-β₁, -β₂, and -β₃ mRNA and Protein in the Murine Lung

1991 • 127 citations

Possible Mechanisms of Bleomycin-Induced Fibrosis

1990 • 106 citations

Bleomycin stimulation of cytokine secretion by the human alveolar macrophage

1992 • 99 citations

C-C chemokines: novel mediators of the profibrotic inflammatory response to bleomycin challenge.

1996 • 91 citations

SpontaneousIn VitroRelease of Alveolar-Macrophage Cytokines after the Intratracheal Instillation of Bleomycin in Rats: Characterization and Kinetic Studies

1988 • 86 citations

Interleukin-2-induced Tumor Necrosis Factor-alpha (TNF-α) Gene Expression in Human Alveolar Macrophages and Blood Monocytes

1989 • 85 citations

Macrophage Markers in Diagnostic Neuropathology

1992 • 73 citations

Exacerbation of murine Pneumocystis carinii infection by adenoviral-mediated gene transfer of a TNF inhibitor.

1997 • 69 citations

Symptomatic Treatment of Recurrent Malignant Pleural Effusions with Intrapleurally AdministeredCorynebacterium parvum

1987 • 54 citations

Intratracheal versus intravenous administration of bleomycin in mice: Acute effects*1

1986 • 50 citations

Changes in distribution, morphology, and tumor necrosis factor-alpha secretion of alveolar macrophage subpopulations during the development of bleomycin-induced pulmonary fibrosis.

1992 • 40 citations

Expression of Osteopontin in a Macrophage Cell Line and in Transgenic Mice with Pulmonary Fibrosis Resulting from the Lung Expression of a Tumor Necrosis Factor‐α Transgene

1995 • 37 citations

The effects of bleomycin on alveolar macrophage growth factor secretion.

1989 • 30 citations

Murine Strain Differences in Acute Lung Injury and Activation of Poly(ADP-ribose) Polymerase by In Vitro Exposure of Lung Slices to Bleomycin

1992 • 30 citations

Developmental Changes in Tropoelastin mRNA Levels in Rat Lung: Evaluation by In Situ Hybridization

1991 • 29 citations