Activation of the inducible form of nitric oxide synthase in the brains of patients with multiple sclerosis.

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Current Protocols in Molecular Biology

1989 • 1,916 citations

Nitric oxide synthase and neuronal NADPH diaphorase are identical in brain and peripheral tissues.

1991 • 1,872 citations

Peroxynitrite-mediated tyrosine nitration catalyzed by superoxide dismutase

1992 • 1,499 citations

Extensive Nitration of Protein Tyrosines in Human Atherosclerosis Detected by Immunohistochemistry

1994 • 1,138 citations

Molecular cloning and expression of inducible nitric oxide synthase from human hepatocytes.

1993 • 845 citations

Tumor necrosis factor identified in multiple sclerosis brain.

1989 • 793 citations

Identification of lymphotoxin and tumor necrosis factor in multiple sclerosis lesions.

1991 • 735 citations

Evidence for nitric oxide‐mediated oxidative damage in chronic inflammation Nitrotyrosine in serum and synovial fluid from rheumatoid patients

1994 • 718 citations

Quantitation of nitrotyrosine levels in lung sections of patients and animals with acute lung injury.

1994 • 599 citations

Constitutive and inducible nitric oxide synthase gene expression, regulation, and activity in human lung epithelial cells.

1994 • 595 citations

Induction of nitric oxide synthase in demyelinating regions of multiple sclerosis brains

1994 • 570 citations

Induction of Nitric Oxide Synthase in Glial Cells

1992 • 501 citations

Effect of Peroxynitrite on the Mitochondrial Respiratory Chain: Differential Susceptibility of Neurones and Astrocytes in Primary Culture

1995 • 493 citations

Evidence for In Vivo Peroxynitrite Production in Human Acute Lung Injury

1995 • 491 citations

In vivo expression of inducible nitric oxide synthase in experimentally induced neurologic diseases.

1993 • 484 citations

Aminoguanidine, an inhibitor of inducible nitric oxide synthase, ameliorates experimental autoimmune encephalomyelitis in SJL mice.

1994 • 389 citations

Induction of nitric oxide synthase activity in human astrocytes by interleukin-1β and interferon-γ

1993 • 355 citations

Regulation of nitric oxide synthase activity in human immunodeficiency virus type 1 (HIV-1)-infected monocytes: implications for HIV-associated neurological disease.

1995 • 337 citations

Detection of Human Immunodeficiency Virus Type 1 Provirus in Mononuclear Cells by in Situ Polymerase Chain Reaction

1992 • 305 citations

A specific histochemical marker (lectinRicinus communis agglutinin-1) for normal human microglia, and application to routine histopathology

1986 • 208 citations

Multiple sclerosis: Involvement of interferons in lesion pathogenesis

1988 • 188 citations

Nitric Oxide Synthases in Neuronal Cells, Macrophages and Endothelium Are NADPH Diaphorases, but Represent Only a Fraction of Total Cellular NADPH Diaphorase Activity

1993 • 188 citations

Triggering of human monocyte activation through CD69, a member of the natural killer cell gene complex family of signal transducing receptors.

1994 • 174 citations

Nitric oxide localized to spinal cords of mice with experimental allergic encephalomyelitis: an electron paramagnetic resonance study.

1993 • 153 citations

Evaluation of nitrite production by human monocyte-derived macrophages

1992 • 117 citations

Severity of neurological signs and degree of inflammatory lesions in the brains of rats with Borna disease correlate with the induction of nitric oxide synthase

1993 • 99 citations

IDENTIFICATION OF THE NORMAL MICROGLIAL POPULATION IN HUMAN AND RODENT NERVOUS TISSUE USING LECTIN–HISTOCHEMISTRY

1988 • 95 citations

Roles for protein kinases in the induction of nitric oxide synthase in astrocytes

1994 • 71 citations