A comparison of the effects of the novel muscarinic receptor agonists L-689,660 and AF102B in tests of reference and working memory

Identification of a Family of Muscarinic Acetylcholine Receptor Genes

1987 • 1,439 citations

APRIORITY

1961 • 1,293 citations

NEUROTRANSMITTER-RELATED ENZYMES AND INDICES OF HYPOXIA IN SENILE DEMENTIA AND OTHER ABIOTROPHIES

1976 • 1,272 citations

Distinct primary structures, ligand-binding properties and tissue-specific expression of four human muscarinic acetylcholine receptors.

1987 • 766 citations

Antagonist binding properties of five cloned muscarinic receptors expressed in CHO-K1 cells.

1989 • 627 citations

Cholinergic mechanisms in learning, memory and dementia: a review of recent evidence

1991 • 598 citations

The basal forebrain-cortical cholinergic system: interpreting the functional consequences of excitotoxic lesions

1991 • 467 citations

Tacrine in Alzheimer's disease

1991 • 355 citations

Narcotic antagonists in the benzomorphan series

1964 • 323 citations

The Memory Deficits in Alzheimer-Type Dementia: A Review

1986 • 240 citations

Homology of the amyloid beta protein precursor in monkey and human supports a primate model for beta amyloidosis in Alzheimer's disease.

1991 • 217 citations

Delay-dependent short-term memory deficits in aged rats

1988 • 183 citations

Behavioral screening for cognition enhancers: from indiscriminate to valid testing: Part I

1992 • 183 citations

Evidence for a direct cholinergic involvement in the scopolamine-induced amnesia in monkeys: Effects of concurrent administration of physostigmine and methylphenidate with scopolamine

1978 • 179 citations

Behavioral screening for cognition enhancers: from indiscriminate to valid testing: Part II

1992 • 96 citations

No response to high‐dose muscarinic agonist therapy in Alzheimer's disease

1988 • 80 citations

Reversal of age-related cognitive impairments by an M1 cholinergic agonist, AF102B

1990 • 77 citations

The behavioral effects of heptyl physostigmine, a new cholinesterase inhibitor, in tests of long-term and working memory in rodents

1991 • 77 citations

(+-)-cis-2-methyl-spiro(1,3-oxathiolane-5,3')quinuclidine, an M1 selective cholinergic agonist, attenuates cognitive dysfunctions in an animal model of Alzheimer's disease.

1991 • 77 citations

Investigation into atropine‐induced antinociception

1990 • 68 citations

Tetrahydroaminoacridine, 3,4 diaminopyridine and physostigmine: Direct comparison of effects on memory in aged primates

1988 • 62 citations

The scopolamine model of dementia: determination of central cholinomimetic effects of physostigmine on cognition and biochemical markers in man

1988 • 51 citations

Reversal by tetrahydroaminoacridine of scopolamine-induced memory and performance deficits in rats

1991 • 50 citations

Amelioration of Experimental Amnesia (Passive Avoidance Failure) in Rodents by the Selective M1 Agonist AF102B

1988 • 29 citations

L‐689,660, a novel cholinomimetic with functional selectivity for M₁ and M₃ muscarinic receptors

1992 • 23 citations

Synthesis of azabicyclic pyrazine derivatives as muscarinic agonists and the preparation of a chloropyrazine analogue with functional selectivity at sub-types of the muscarinic receptor

1991 • 18 citations

Deleted Work

1955 • 0 citations