The erbB‐3 Gene in human pancreatic cancer

Isolation and characterization of ERBB3, a third member of the ERBB/epidermal growth factor receptor family: evidence for overexpression in a subset of human mammary tumors.

1989 • 742 citations

The type 1 (EGFR-related) family of growth factor receptors and their ligands

1992 • 377 citations

Molecular cloning and expression of an additional epidermal growth factor receptor-related gene.

1990 • 375 citations

Abnormalities of the p53 tumour suppressor gene in human pancreatic cancer

1991 • 375 citations

Intermolecular association of the p185 protein and EGF receptor modulates EGF receptor function

1990 • 362 citations

Synergistic interaction of p185c-neu and the EGF receptor leads to transformation of rodent fibroblasts

1989 • 316 citations

Ki-ras oncogene activation in preinvasive pancreatic cancer

1992 • 250 citations

Heterodimerization of the erbB-1 and erbB-2 receptors in human breast carcinoma cells: a mechanism for receptor transregulation

1990 • 246 citations

Egf binding to its receptor triggers a rapid tyrosine phosphorylation of the erbB-2 protein in the mammary tumor cell line SK-BR-3.

1988 • 226 citations

Transforming growth factor alpha and epidermal growth factor in human pancreatic cancer

1991 • 213 citations

The epidermal growth factor receptor in human pancreatic cancer

1992 • 198 citations

Enhanced expression of epidermal growth factor receptor correlates with alterations of chromosome 7 in human pancreatic cancer.

1986 • 192 citations

Expression of the c-erbB-3 protein in normal human adult and fetal tissues.

1992 • 183 citations

The c‐erbB‐2 proto‐oncogene in human pancreatic cancer

1990 • 172 citations

Oncogenic Activation of p185^neu Stimulates Tyrosine Phosphorylation In Vivo

1988 • 142 citations

Oncogenic activation of p185neu stimulates tyrosine phosphorylation in vivo.

1988 • 87 citations

Pancreatic cancer: the greatest oncological challenge

1988 • 84 citations

Phosphorylation process induced by epidermal growth factor alters the oncogenic and cellular neu (NGL) gene products.

1988 • 76 citations

Expression of c-erbB-2 in Human Pancreatic Adenocarcinomas

1991 • 66 citations

Mutational activation of the c-K-ras gene in human pancreatic carcinoma

1990 • 54 citations

Differential binding and biological activities of epidermal growth factor and transforming growth factor alpha in a human pancreatic cancer cell line.

1991 • 37 citations