Ki-ras oncogene activation in preinvasive pancreatic cancer

Genetic Alterations during Colorectal-Tumor Development

1988 • 6,691 citations

ras oncogenes in human cancer: a review.

1989 • 5,116 citations

Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes

1988 • 2,121 citations

Prevalence of ras gene mutations in human colorectal cancers

1987 • 1,866 citations

Detection of high incidence of K-ras oncogenes during human colon tumorigenesis

1987 • 1,074 citations

KRAS codon 12 mutations occur very frequently in pancreatic adenocarcinomas

1988 • 620 citations

High frequency of ras oncogene activation in all stages of human thyroid tumorigenesis.

1989 • 414 citations

Morphological lesions associated with human primary invasive nonendocrine pancreas cancer.

1976 • 346 citations

Relation of pancreatic duct hyperplasia to carcinoma

1979 • 322 citations

High frequency of Ki‐ras codon 12 mutations in pancreatic adenocarcinomas

1989 • 295 citations

Presence of mutations in all three ras genes in human thyroid tumors.

1990 • 250 citations

Morphological patterns of primary nonendocrine human pancreas carcinoma.

1975 • 228 citations

Intraductal papillary neoplasms of the pancreas. A clinicopathologic study of six patients

1989 • 212 citations

RAS mutations in myelodysplasia detected by amplification, oligonucleotide hybridization, and transformation.

1988 • 162 citations

Intraductal proliferation in the pancreas and its relationship to human and experimental carcinogenesis

1980 • 156 citations

Clinical application of ras gene mutation for diagnosis of pancreatic adenocarcinoma

1991 • 148 citations

Detection of c-K-ras mutations in fine needle aspirates from human pancreatic adenocarcinomas.

1990 • 132 citations

Frequency and Types of Point Mutation at the 12th Codon of the c‐Ki‐ras Gene Found in Pancreatic Cancers from Japanese Patients

1989 • 128 citations

Ras gene mutations in intraductal papillary neoplasms of the pancreas. Analysis in five cases

1991 • 118 citations

Histopathology in the Evaluation of Total Pancreatectomy for Ductal Carcinoma

1979 • 104 citations

Pancreatic ductal adenocarcinomas induced in syrian hamsters by N‐nitrosobis (2‐oxopropyl) amine contain a c‐Ki‐ras oncogene with a point‐mutated codon 12

1990 • 97 citations

Diffuse Intraductal Papillary Adenocarcinoma of the Pancreas

1987 • 69 citations

Ductal adenocarcinoma of the head of the pancreas: incidence of tumor involvement beyond the Whipple resection line. Histological and immunocytochemical analysis of 37 total pancreatectomy specimens.

1987 • 68 citations

Histogenesis of pancreatic carcinomas: A study based on 248 cases

1985 • 67 citations

Classification and Staging of Pancreatic Nonendocrine Tumors

1989 • 65 citations

Agent-specific ras oncogene activation in rat thyroid tumours.

1988 • 55 citations

Ductal Adenocarcinoma of the Head of the Pancreas

1987 • 55 citations

Mutational activation of the c-K-ras gene in human pancreatic carcinoma

1990 • 54 citations

Direct sequencing analysis of exon 1 of the c-K-ras gene shows a low frequency of mutations in human pancreatic adenocarcinomas.

1989 • 45 citations

Growth factors and oncogenes in pancreatic cancer

1990 • 40 citations

Molecular biology of cancer genes

1991 • 34 citations

Activation of c‐Ki‐ras not detectable in adenomas or adenocarcinomas arising in rat pancreas

1990 • 34 citations

Activation of K-ras in transplantable pancreatic ductal adenocarcinomas of Syrian golden hamsters

1990 • 32 citations

Direct sequencing analysis of exon 1 of the c-K-ras gene shows a low frequency of mutations in human pancreatic adenocarcinomas.

1989 • 25 citations

IN SITU CARCINOMA OF THE PANCREAS

1986 • 23 citations

Molecular differences between human and experimental pancreaticobiliary diversion-induced rat pancreatic neoplasia.

1991 • 11 citations