The varied lifestyles of intracellular pathogens within eukaryotic vacuolar compartments

Mechanisms of intracellular protein transport

1994 • 2,280 citations

The Biogenesis of Lysosomes

1989 • 1,583 citations

Lack of Acidification inMycobacteriumPhagosomes Produced by Exclusion of the Vesicular Proton-ATPase

1994 • 1,289 citations

RESPONSE OF CULTURED MACROPHAGES TO MYCOBACTERIUM TUBERCULOSIS, WITH OBSERVATIONS ON FUSION OF LYSOSOMES WITH PHAGOSOMES

1971 • 973 citations

Role of hemolysin for the intracellular growth of Listeria monocytogenes.

1988 • 881 citations

Interaction of chlamydiae and host cells in vitro

1991 • 734 citations

The Legionnaires' disease bacterium (Legionella pneumophila) inhibits phagosome-lysosome fusion in human monocytes.

1983 • 704 citations

Characterization of the Mycobacterium tuberculosis phagosome and evidence that phagosomal maturation is inhibited.

1995 • 680 citations

Biogenesis of phagolysosomes proceeds through a sequential series of interactions with the endocytic apparatus

1994 • 676 citations

Formation of a novel phagosome by the Legionnaires' disease bacterium (Legionella pneumophila) in human monocytes.

1983 • 644 citations

Two distinct defects in intracellular growth complemented by a single genetic locus in Legionella pneumophila

1993 • 633 citations

Professional and non-professional phagocytes: an introduction

1995 • 521 citations

A rab protein is required for the assembly of SNARE complexes in the docking of transport vesicles

1994 • 501 citations

Lysosome recruitment and fusion are early events required for trypanosome invasion of mammalian cells

1992 • 393 citations

Legionella pneumophila inhibits acidification of its phagosome in human monocytes.

1984 • 384 citations

Membrane fusion machinery: Insights from synaptic proteins

1993 • 380 citations

Pathogenesis of tuberculosis: interaction of Mycobacterium tuberculosis with macrophages

1993 • 373 citations

Friends and family: The role of the rab GTPases in vesicular traffic

1993 • 364 citations

Intracellular trafficking in Mycobacterium tuberculosis and Mycobacterium avium-infected macrophages.

1994 • 358 citations

Salmonella stimulate macrophage macropinocytosis and persist within spacious phagosomes.

1994 • 349 citations

Phagocytosis of the legionnaires' disease bacterium (legionella pneumophila) occurs by a novel mechanism: Engulfment within a Pseudopod coil

1984 • 317 citations

IpaB of Shigella flexneri causes entry into epithelial cells and escape from the phagocytic vacuole.

1992 • 316 citations

Phagocytosis by zippers and triggers

1995 • 314 citations

Inhibition of macrophage phagosome-lysosome fusion by Salmonella typhimurium

1991 • 271 citations

Targeting of Salmonella typhimurium to vesicles containing lysosomal membrane glycoproteins bypasses compartments with mannose 6-phosphate receptors.

1995 • 256 citations

Parasitophorous vacuoles of Leishmania amazonensis-infected macrophages maintain an acidic pH

1990 • 234 citations

Direct access to serum macromolecules by intraerythrocytic malaria parasites

1991 • 223 citations

The Toxoplasma gondii rhoptry protein ROP 2 is inserted into the parasitophorous vacuole membrane, surrounding the intracellular parasite, and is exposed to the host cell cytoplasm.

1994 • 222 citations

A nutrient-permeable channel on the intraerythrocytic malaria parasite

1993 • 222 citations

Histoplasma capsulatum modulates the acidification of phagolysosomes.

1993 • 197 citations

Kinetics and pattern of organelle exocytosis duringToxoplasma gondii/host-cell interaction

1993 • 190 citations

Plasmodium falciparum exports the Golgi marker sphingomyelin synthase into a tubovesicular network in the cytoplasm of mature erythrocytes

1994 • 173 citations

Intracellular trafficking and the parasitophorous vacuole of Leishmania mexicana-infected macrophages

1992 • 168 citations

Tandemly repeated genes encode nucleoside triphosphate hydrolase isoforms secreted into the parasitophorous vacuole of Toxoplasma gondii.

1994 • 157 citations

The origin of parasitophorous vacuole membrane lipids in malaria-infected erythrocytes

1993 • 145 citations

Phagolysosomes of Coxiella burnetii-infected cell lines maintain an acidic pH during persistent infection

1992 • 139 citations

Desialylation of lysosomal membrane glycoproteins by Trypanosoma cruzi: a role for the surface neuraminidase in facilitating parasite entry into the host cell cytoplasm.

1992 • 135 citations

Salmonella invasion of nonphagocytic cells induces formation of macropinosomes in the host cell

1994 • 132 citations

Membrane trafficking along the phagocytic pathway

1995 • 130 citations

Virulence factors of the family Legionellaceae

1992 • 124 citations

Toxoplasma gondii: a protozoan for the nineties

1993 • 122 citations

Plasmodium falciparum: - The Pf332 Antigen Is Secreted from the Parasite by a Brefeldin A-Dependent Pathway and Is Translocated to the Erythrocyte Membrane via the Maurer′s Clefts

1994 • 116 citations

Growth rate paradox of Salmonella typhimurium within host macrophages

1993 • 113 citations

Implication of phagosome-lysosome fusion in restriction of Mycobacterium avium growth in bone marrow macrophages from genetically resistant mice

1993 • 112 citations

Inhibition of phagosome-lysosome fusion in macrophages by certain mycobacteria can be explained by inhibition of lysosomal movements observed after phagocytosis.

1987 • 109 citations

Phagolysosome Formation, Cyclic Adenosine 3':5'-Monophosphate and the Fate of Salmonella typhimurium within Mouse Peritoneal Macrophages

1979 • 106 citations

Membrane sorting during phagocytosis: selective exclusion of major histocompatibility complex molecules but not complement receptor CR3 during conventional and coiling phagocytosis.

1992 • 87 citations

Leishmania donovani-infected macrophages: characterization of the parasitophorous vacuole and potential role of this organelle in antigen presentation

1994 • 86 citations

Salmonella typhimurium induces selective aggregation and internalization of host cell surface proteins during invasion of epithelial cells

1994 • 83 citations

A soluble secretory protein of the intracellular parasite Toxoplasma gondii associates with the parasitophorous vacuole membrane through hydrophobic interactions.

1994 • 82 citations

Phagosome-Lysosome Fusion in P388D1 Macrophages Infected With Histoplasma capsulatum

1988 • 81 citations

Localization of major histocompatibility complex class II molecules in phagolysosomes of murine macrophages infected with Leishmania amazonensis

1991 • 79 citations

Penetration of Toxoplasma gondii into Host Cells Induces Changes in the Distribution of the Mitochondria and the Endoplasmic Reticulum.

1992 • 78 citations

Interactions between Live Bartonella bacilliformis and Endothelial Cells

1992 • 74 citations

Invasion of vertebrate cells by Toxoplasma gondii

1995 • 68 citations

Distribution of mhc class i and of mhc class ii molecules in macrophages infected with Leishmania amazonensis

1994 • 58 citations

pH dependence of the Coxiella burnetii glutamate transport system

1983 • 55 citations

Acidification of Phagosomes in Murine Macrophages: Blockage by Nocardia asteroides

1986 • 49 citations

Selective translocation of annexins during intracellular redistribution of Chlamydia trachomatis in HeLa and McCoy cells

1994 • 46 citations

Hypoexpression of major histocompatibility complex molecules on Legionella pneumophila phagosomes and phagolysosomes

1993 • 44 citations

Identification of outer membrane proteins of Bartonella bacilliformis

1994 • 42 citations

Characterization of host cell-derived membrane proteins of the vacuole surrounding different intracellular forms of Trypanosoma cruzi in J774 cells. Evidence for phagocyte receptor sorting during the early stages of parasite entry.

1991 • 36 citations

Ducts, channels and transporters in Plasmodium-infected erythrocytes

1994 • 29 citations

Elimination of hydrogen peroxide by Haemophilus somnus, a catalase-negative pathogen of cattle

1991 • 19 citations