Sex difference in methylation of single-copy genes in human meiotic germ cells: Implications for X chromosome inactivation, parental imprinting, and origin of CpG mutations

Completion of mouse embryogenesis requires both the maternal and paternal genomes

1984 • 1,529 citations

Development of reconstituted mouse eggs suggests imprinting of the genome during gametogenesis

1984 • 1,402 citations

Forensic application of DNA ‘fingerprints’

1985 • 1,163 citations

Isolation and characterization of genomic and cDNA clones of human erythropoietin

1985 • 1,101 citations

Temporal and regional changes in DNA methylation in the embryonic, extraembryonic and germ cell lineages during mouse embryo development

1987 • 1,088 citations

A quantitative and cytological study of germ cells in human ovaries

1963 • 1,074 citations

The CpG dinucleotide and human genetic disease

1988 • 946 citations

Genetic imprinting suggested by maternal heterodisomy in non-deletion Prader-Willi syndrome

1989 • 887 citations

Differential activity of maternally and paternally derived chromosome regions in mice

1985 • 708 citations

Human testis-specific PGK gene lacks introns and possesses characteristics of a processed gene

1987 • 489 citations

Parental legacy determines methylation and expression of an autosomal transgene: A molecular mechanism for parental imprinting

1987 • 478 citations

The anatomy and histology of XO human embryos and fetuses

1966 • 446 citations

Methylation of the Hprt gene on the inactive X occurs after chromosome inactivation

1987 • 363 citations

The gene structure of human anti-haemophilic factor IX.

1984 • 361 citations

Methylation of the hypoxanthine phosphoribosyltransferase locus on the human X chromosome: implications for X-chromosome inactivation.

1984 • 305 citations

Sequential X chromosome inactivation coupled with cellular differentiation in early mouse embryos

1979 • 284 citations

Differences in DNA methylation during oogenesis and spermatogenesis and their persistence during early embryogenesis in the mouse.

1987 • 278 citations

Differential methylation of hypoxanthine phosphoribosyltransferase genes on active and inactive human X chromosomes.

1984 • 226 citations

Inheritance of allelic blueprints for methylation patterns

1988 • 172 citations

DNA methylation stabilizes X chromosome inactivation in eutherians but not in marsupials: evidence for multistep maintenance of mammalian X dosage compensation.

1987 • 171 citations

Structural organization of the human alpha-galactosidase A gene: further evidence for the absence of a 3' untranslated region.

1988 • 165 citations

Active X chromosome DNA is unmethylated at eight CCGG sites clustered in a guanine-plus-cytosine-rich island at the 5' end of the gene for phosphoglycerate kinase.

1986 • 164 citations

Methylation patterns of repetitive DNA sequences in germ cells ofMus muscutus

1984 • 126 citations

Epigenetic and genetic factors affect transgene methylation imprinting

1989 • 123 citations

Chromatin Structure and de Novo Methylation of Sperm DNA: Implications for Activation of the Paternal Genome

1985 • 119 citations

Expression of the G6PD locus on the human X chromosome is associated with demethylation of three CpG islands within 100 kb of DNA.

1988 • 119 citations

Incomplete X chromosome dosage compensation in chorionic villi of human placenta.

1985 • 103 citations

Observations on the Movements of the Living Primordial Germ Cells in the Mouse

1963 • 101 citations

QUANTIFICATION OF HUMAN SEMINIFEROUS EPITHELIUM

1973 • 97 citations

Complete concordance between glucose-6-phosphate dehydrogenase activity and hypomethylation of 3′ CpG clusters: implications for X chromosome dosage compensation

1984 • 92 citations

Histology of the Ovary

1987 • 90 citations

X chromosome reactivation in oocytes of Mus caroli.

1981 • 84 citations

Evidence for two functional X chromosomes in human oocytes

1972 • 80 citations

Somatic and germ-cell sex in mammals

1988 • 63 citations

Complete reactivation of X chromosomes from human chorionic villi with a switch to early DNA replication.

1986 • 58 citations

Evidence for two active X chromosomes in germ cells of female before meiotic entry

1977 • 50 citations

THE NORMAL OVARY OF CHILDHOOD

1967 • 48 citations

CpG islands of the X chromosome are gene associated

1988 • 47 citations

Comparison of factor IX methylation on human active and inactive X chromosomes: implications for X inactivation and transcription of tissue-specific genes.

1986 • 42 citations

Frequent derepression of G6PD and HPRT on the Marsupial inactive X chromosome associated with cell proliferation in vitro

1989 • 41 citations

X-Linked Gene Expression in the Virginia Opossum: Differences Between the Paternally Derived Gpd and Pgk-A Loci

1987 • 38 citations

Signal sequence and DNA‐mediated expression of human lysosomal α‐galactosidase A

1987 • 31 citations

A study of X chromosome regulation during oogenesis in the mouse

1978 • 30 citations

An Xba I polymorphism 3′ to the human erythropoietin (EPO) gene

1987 • 10 citations