Binding of the synaptic vesicle v-SNARE, synaptotagmin, to the plasma membrane t-SNARE, SNAP-25, can explain docked vesicles at neurotoxin-treated synapses

SNAP receptors implicated in vesicle targeting and fusion

1993 • 3,220 citations

Mechanisms of intracellular protein transport

1994 • 2,280 citations

The synaptic vesicle cycle: a cascade of protein–protein interactions

1995 • 2,004 citations

A protein assembly-disassembly pathway in vitro that may correspond to sequential steps of synaptic vesicle docking, activation, and fusion

1993 • 1,893 citations

Syntaxin: A Synaptic Protein Implicated in Docking of Synaptic Vesicles at Presynaptic Active Zones

1992 • 1,274 citations

Protein Sorting by Transport Vesicles

1996 • 1,168 citations

Synaptotagmin: a Calcium Sensor on the Synaptic Vesicle Surface

1992 • 968 citations

Targeted expression of tetanus toxin light chain in Drosophila specifically eliminates synaptic transmission and causes behavioral defects

1995 • 921 citations

Synaptic vesicle membrane fusion complex: action of clostridial neurotoxins on assembly.

1994 • 798 citations

Synaptic vesicle fusion complex contains unc-18 homologue bound to syntaxin

1993 • 716 citations

Specificity and regulation of a synaptic vesicle docking complex

1994 • 601 citations

Ca2+-dependent and -independent activities of neural and non-neural synaptotagmins

1995 • 597 citations

Identification of a synaptic vesicle-specific membrane protein with a wide distribution in neuronal and neurosecretory tissue.

1981 • 560 citations

A single C2 domain from synaptotagmin I is sufficient for high affinity Ca2+/phospholipid binding.

1993 • 486 citations

Synaptotagmin I is a high affinity receptor for clathrin AP-2: Implications for membrane recycling

1994 • 483 citations

Structure and function of tetanus and botulinum neurotoxins

1995 • 470 citations

Syntaxin and synaptobrevin function downstream of vesicle docking in drosophila

1995 • 389 citations

Ca2+ Regulates the Interaction between Synaptotagmin and Syntaxin 1

1995 • 372 citations

Calcium-dependent interaction of N-type calcium channels with the synaptic core complex

1996 • 350 citations

Identification and structure of four yeast genes (SLY) that are able to suppress the functional loss of YPT1, a member of the RAS superfamily.

1991 • 347 citations

Isoform-specific interaction of the alpha1A subunits of brain Ca2+ channels with the presynaptic proteins syntaxin and SNAP-25.

1996 • 321 citations

Calcium-dependent switching of the specificity of phosphoinositide binding to synaptotagmin

1996 • 290 citations

SNAP-25, a t-SNARE which binds to both syntaxin and synaptobrevin via domains that may form coiled coils.

1994 • 288 citations

HPC-1 is associated with synaptotagmin and omega-conotoxin receptor.

1992 • 275 citations

Functional interaction of syntaxin and SNAP-25 with voltage-sensitive L- and N-type Ca2+ channels.

1996 • 273 citations

A post-docking role for synaptobrevin in synaptic vesicle fusion

1994 • 255 citations

Binding of synaptotagmin to the α-latrotoxin receptor implicates both in synaptic vesicle exocytosis

1991 • 251 citations

The synaptic vesicle protein synaptotagmin associates with calcium channels and is a putative Lambert-Eaton myasthenic syndrome antigen.

1992 • 220 citations

Calcium-dependent interaction of the cytoplasmic region of synaptotagmin with membranes. Autonomous function of a single C2-homologous domain.

1994 • 209 citations

Functional properties of multiple synaptotagmins in brain

1994 • 195 citations

A possible docking and fusion particle for synaptic transmission

1995 • 177 citations

BET1, BOS1, and SEC22 Are Members of a Group of Interacting Yeast Genes Required for Transport from the Endoplasmic Reticulum to the Golgi Complex

1990 • 176 citations

Interaction of synaptotagmin with the cytoplasmic domains of neurexins

1993 • 170 citations

SNAP-25 Is Required for a Late Postdocking Step in Ca2+-dependent Exocytosis

1996 • 148 citations

The BOS1 gene encodes an essential 27-kD putative membrane protein that is required for vesicular transport from the ER to the Golgi complex in yeast.

1991 • 97 citations

Identification and Structure of Four Yeast Genes (SLY) That Are Able To Suppress the Functional Loss of YPT1, a Member of the RAS Superfamily

1991 • 97 citations

SNAP-25 and synaptotagmin involvement in the final Ca(2+)-dependent triggering of neurotransmitter exocytosis.

1996 • 94 citations

[39] Tetanus and botulism neurotoxins: Isolation and assay

1995 • 87 citations

SNAREs and targeted membrane fusion

1995 • 51 citations

Neural Transmission: Synaptotagmin is just a calcium sensor

1995 • 45 citations