Human microglia activate lymphoproliferative responses to recall viral antigens

Perivascular Microglial Cells of the CNS Are Bone Marrow-Derived and Present Antigen in Vivo

1988 • 1,451 citations

Antigen presentation and tumor cytotoxicity by interferon‐γ‐treated microglial cells

1987 • 648 citations

Normal adult ramified microglia separated from other central nervous system macrophages by flow cytometric sorting. Phenotypic differences defined and direct ex vivo antigen presentation to myelin basic protein-reactive CD4+ T cells compared.

1995 • 622 citations

Specific Tropism of HIV-1 for Microglial Cells in Primary Human Brain Cultures

1990 • 343 citations

Microglia are the major cell type expressing MHC class II in human white matter

1987 • 302 citations

Biology of Adult Human Microglia in Culture: Comparisons with Peripheral Blood Monocytes and Astrocytes

1992 • 162 citations

Microglia in the immune surveillance of the brain: Human microglia constitutively express HLA-DR molecules

1993 • 134 citations

Presentation of myelin basic protein by murine cerebral vascular endothelial cells.

1985 • 129 citations

Major histocompatibility complex-expressing nonhematopoietic astroglial cells prime only CD8+ T lymphocytes: astroglial cells as perpetuators but not initiators of CD4+ T cell responses in the central nervous system.

1991 • 107 citations

Human T-cell leukemia virus type I infection of monocytes and microglial cells in primary human cultures.

1992 • 106 citations

Pathways of viral antigen processing and presentation to CTL: defined by the mode of virus entry?

1989 • 79 citations

Induction of primary T cell responses by human glial cells

1993 • 77 citations

Antigen presentation by human fetal astrocytes with the cooperative effect of microglia or the microglial-derived cytokine IL-1

1995 • 62 citations

Cytokine-gene expression in measles-infected adult human glial cells

1994 • 42 citations

Adult human glial cells can present target antigens to HLA-restricted cytotoxic T-cells

1990 • 33 citations

Granulocyte-macrophage colony stimulating factor inhibits class II major histocompatibility complex expression and antigen presentation by microglia

1993 • 26 citations

Rapidly Progressive Subacute Sclerosing Panencephalitis: An Ultrastructural and Immunoperoxidase Study

1984 • 13 citations