Adult human glial cells can present target antigens to HLA-restricted cytotoxic T-cells

Restriction of in vitro T cell-mediated cytotoxicity in lymphocytic choriomeningitis within a syngeneic or semiallogeneic system

1974 • 2,058 citations

Astrocytes present myelin basic protein to encephalitogenic T-cell lines

1984 • 773 citations

Inducible expression of H–2 and Ia antigens on brain cells

1984 • 656 citations

Heterogeneity of Genotypic and Phenotypic Characteristics of Fifteen Permanent Cell Lines Derived from Human Gliomas

1981 • 487 citations

Brefeldin A implicates egress from endoplasmic reticulum in class I restricted antigen presentation

1989 • 317 citations

Adoptive transfer of myelin basic protein-sensitized T cells produces chronic relapsing demyelinating disease in mice

1984 • 311 citations

Microglia are the major cell type expressing MHC class II in human white matter

1987 • 302 citations

Antigen presentation by interferon-gamma-treated endothelial cells and fibroblasts: differential ability to function as antigen-presenting cells despite comparable Ia expression.

1985 • 264 citations

Cytoimitiunotherapy for persistent virus infection reveals a unique clearance pattern from the central nervous system

1986 • 250 citations

Viral particles induce Ia antigen expression on astrocytes

1986 • 241 citations

Ia-restricted encephalitogenic T lymphocytes mediating EAE lyse autoantigen-presenting astrocytes

1986 • 214 citations

Multiple sclerosis: relevance of Class I and Class II MHC-expressing cells to lesion development

1987 • 169 citations

DISTRIBUTION AND QUANTITATION OF HLA-ABC AND DR (Ia) ANTIGENS ON HUMAN KIDNEY AND OTHER TISSUES

1980 • 165 citations

Immune‐Mediated Encephalitis: On the Role of Antigen‐Presenting Cells in Brain Tissue

1987 • 155 citations

Induction and functional characterization of class II MHC (Ia) antigens on murine keratinocytes.

1988 • 142 citations

Presentation of myelin basic protein by murine cerebral vascular endothelial cells.

1985 • 129 citations

Immunological reactions induced by intracerebral transplantation: Evidence that host microglia but not astroglia are the antigen-presenting cells

1989 • 93 citations

Immunohistochemical studies of adult human glial cells

1989 • 89 citations

Astrocytes and intracerebral immune responses

1989 • 70 citations

Antigenic Heterogeneity of Human Anaplastic Gliomas and Glioma-derived Cell Lines Defined by Monoclonal Antibodies

1985 • 65 citations

Inducibility of Ia antigen on astrocytes by murine coronavirus JHM is rat strain dependent.

1987 • 42 citations

Induction of human leukocyte antigen-A,B,C and -DR on cultured human oligodendrocytes and astrocytes by human γ-interferon

1986 • 29 citations

Site-directed mutagenesis of an HLA-A3 gene identifies amino acid 152 as crucial for major-histocompatibility-complex-restricted and alloreactive cytotoxic-T-lymphocyte recognition.

1987 • 29 citations

The role of the human major histocompatibility complex in cytotoxic T-cell responses to virus-infected cells

1982 • 28 citations

Impaired human leukocyte antigen–restricted measles virus–specific cytotoxic T‐cell response in subacute sclerosing panencephalitis

1989 • 27 citations

Cytotoxic T Cells in Autoimmune Disease of the Central Nervous System^a

1988 • 8 citations