Quetiapine

A RATING SCALE FOR DEPRESSION

1960 • 30,921 citations

Lifetime Prevalence and Age-of-Onset Distributions of DSM-IV Disorders in the National Comorbidity Survey Replication

2005 • 18,882 citations

A New Depression Scale Designed to be Sensitive to Change

1979 • 12,729 citations

THE ASSESSMENT OF ANXIETY STATES BY RATING

1959 • 10,517 citations

A Rating Scale for Mania: Reliability, Validity and Sensitivity

1978 • 8,000 citations

Prevalence and Co-occurrence of Substance Use Disorders and IndependentMood and Anxiety Disorders

2004 • 2,808 citations

The Long-term Natural History of the Weekly Symptomatic Status of Bipolar I Disorder

2002 • 2,037 citations

A Prospective Investigation of the Natural History of the Long-term Weekly Symptomatic Status of Bipolar II Disorder

2003 • 1,195 citations

Does Fast Dissociation From the Dopamine D₂ Receptor Explain the Action of Atypical Antipsychotics?: A New Hypothesis

2001 • 1,113 citations

Excess Mortality in Bipolar and Unipolar Disorder in Sweden

2001 • 1,107 citations

Efficacy of Olanzapine and Olanzapine-Fluoxetine Combination in the Treatment of Bipolar I Depression

2003 • 891 citations

A Randomized, Double-Blind, Placebo-Controlled Trial of Quetiapine in the Treatment of Bipolar I or II Depression

2005 • 860 citations

Columbia Classification Algorithm of Suicide Assessment (C-CASA): Classification of Suicidal Events in the FDA’s Pediatric Suicidal Risk Analysis of Antidepressants

2007 • 786 citations

Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) collaborative update of CANMAT guidelines for the management of patients with bipolar disorder: update 2009

2009 • 570 citations

Efficacy of Quetiapine Monotherapy in Bipolar I and II Depression

2006 • 555 citations

The Increasing Medical Burden in Bipolar Disorder

2005 • 486 citations

Adverse Effects of Atypical Antipsychotics

2007 • 413 citations

A Double-Blind, Placebo-Controlled Study of Quetiapine and Lithium Monotherapy in Adults in the Acute Phase of Bipolar Depression (EMBOLDEN I)

2010 • 366 citations

Clinical Pharmacokinetics of Quetiapine

2001 • 362 citations

N-Desalkylquetiapine, a Potent Norepinephrine Reuptake Inhibitor and Partial 5-HT1A Agonist, as a Putative Mediator of Quetiapine's Antidepressant Activity

2007 • 307 citations

A Double-Blind, Placebo-Controlled Study of Quetiapine and Paroxetine as Monotherapy in Adults With Bipolar Depression (EMBOLDEN II)

2010 • 300 citations

Canadian Network for Mood and Anxiety Treatments (CANMAT) guidelines for the management of patients with bipolar disorder: update 2007

2006 • 262 citations

Atypical antipsychotic drugs, quetiapine, iloperidone, and melperone, preferentially increase dopamine and acetylcholine release in rat medial prefrontal cortex: role of 5-HT1A receptor agonism

2002 • 196 citations

World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for Biological Treatment of Bipolar Disorders, Part I: Treatment of Bipolar Depression

2002 • 189 citations

Time course of central nervous dopamine-D 2 and 5-HT 2 receptor blockade and plasma drug concentrations after discontinuation of quetiapine (Seroquel ® ) in patients with schizophrenia

1998 • 167 citations

Continuation of Quetiapine Versus Switching to Placebo or Lithium for Maintenance Treatment of Bipolar I Disorder

2011 • 162 citations

Atypical antipsychotics in bipolar depression: potential mechanisms of action.

2005 • 156 citations

Effects of cytochrome P450 3A modulators ketoconazole and carbamazepine on quetiapine pharmacokinetics

2005 • 152 citations

Effectiveness of the extended release formulation of quetiapine as monotherapy for the treatment of acute bipolar depression

2011 • 146 citations

D2 and 5HT2A receptor occupancy of different doses of quetiapine in schizophrenia: a PET study

2001 • 139 citations

A double‐blind, placebo‐controlled pilot study of quetiapine for depressed adolescents with bipolar disorder

2009 • 121 citations

Evaluation of antipsychotic drugs as inhibitors of multidrug resistance transporter P-glycoprotein

2006 • 118 citations

A Survey of Reports of Quetiapine-Associated Hyperglycemia and Diabetes Mellitus

2004 • 118 citations

Efficacy of modern antipsychotics in placebo-controlled trials in bipolar depression: a meta-analysis

2009 • 118 citations

Quetiapine monotherapy in the treatment of patients with bipolar I or II depression and a rapid‐cycling disease course: a randomized, double‐blind, placebo‐controlled study

2007 • 110 citations

Quetiapine in the Treatment of Anxiety in Patients With Bipolar I or II Depression

2006 • 110 citations

Influence of age, gender, body weight and valproate comedication on quetiapine plasma concentrations

2006 • 101 citations

Pharmacokinetic profiles of extended release quetiapine fumarate compared with quetiapine immediate release

2008 • 97 citations

Long-term effects of olanzapine, risperidone, and quetiapine on serotonin 1A, 2A and 2C receptors in rat forebrain regions

2002 • 94 citations

The clinical relevance of changes in the Montgomery–Asberg Depression Rating Scale using the minimum clinically important difference approach

2008 • 86 citations

Long-term lithium treatment in the prevention of suicidal behavior in bipolar disorder patients

2009 • 75 citations

Quetiapine for the treatment of bipolar II depression: Analysis of data from two randomized, double-blind, placebo-controlled studies

2008 • 69 citations

The Safety and Pharmacokinetics of Quetiapine When Coadministered With Haloperidol, Risperidone, or Thioridazine

2002 • 68 citations

A preclinical and clinical rationale for quetiapine in mood syndromes

2007 • 67 citations

A 24-Week, Multicenter, Open-Label, Randomized Study to Compare Changes in Glucose Metabolism in Patients With Schizophrenia Receiving Treatment With Olanzapine, Quetiapine, or Risperidone

2009 • 60 citations

Single-dose pharmacokinetics of quetiapine in subjects with renal or hepatic impairment

2000 • 59 citations

International therapeutic guidelines for bipolar disorder

2007 • 57 citations

Efficacy and acceptability of mood stabilisers in the treatment of acute bipolar depression: systematic review

2010 • 56 citations

Self-reported sedation profile of immediate-release quetiapine fumarate compared with extended-release quetiapine fumarate during dose initiation: A randomized, double-blind, crossover study in healthy adult subjects

2009 • 54 citations

Treatment Research in Bipolar Disorder

2002 • 52 citations

Quetiapine Extended-Release Versus Immediate-Release Formulation

2008 • 50 citations

Quetiapine

2008 • 45 citations

Effect of Fluoxetine and Imipramine on the Pharmacokinetics and Tolerability of the Antipsychotic Quetiapine

2002 • 43 citations

A randomised, placebo-controlled 52-week trial of continued quetiapine treatment in recently depressed patients with bipolar I and bipolar II disorder

2012 • 43 citations

Pharmacotherapy of bipolar depression: An update

2006 • 41 citations

Number needed to treat and time to response/remission for quetiapine monotherapy efficacy in acute bipolar depression: evidence from a large, randomized, placebo-controlled study

2007 • 38 citations

Open‐label steady‐state pharmacokinetic drug interaction study on co‐administered quetiapine fumarate and divalproex sodium in patients with schizophrenia, schizoaffective disorder, or bipolar disorder

2007 • 31 citations

Quetiapine

2007 • 30 citations

The under-recognized role of dopamine in the treatment of major depressive disorder

2008 • 29 citations

Quetiapine monotherapy for bipolar depression

2008 • 27 citations

Open-label study of the effect of combination quetiapine/lithium therapy on lithium pharmacokinetics and tolerability

2002 • 22 citations

Cost Effectiveness of Adjunctive Quetiapine Fumarate Extended-Release Tablets with Mood Stabilizers in the Maintenance Treatment of Bipolar I Disorder

2010 • 19 citations

An analysis of the efficacy of treatments for bipolar depression.

2008 • 12 citations

P.1.e.019 PET-measured occupancy of the norepinephrene transporter by extended release quetiapine fumarate (quetiapine XR) in brains of healthy subjects

2008 • 12 citations

Effective Agents in Treating Bipolar Depression

2008 • 5 citations