Histone structure and function

Involvement of histone H1 in the organization of the nucleosome and of the salt-dependent superstructures of chromatin.

1979 • 1,532 citations

Structure of the nucleosome core particle at 7 Å resolution

1984 • 1,028 citations

Sequence periodicities in chicken nucleosome core DNA

1986 • 930 citations

A direct link between core histone acetylation and transcriptionally active chromatin.

1988 • 905 citations

Structure of nucleosome core particles of chromatin

1977 • 746 citations

The structure of histone H1 and its location in chromatin

1980 • 696 citations

Alternative chromatin structure at CpG islands

1990 • 480 citations

Extremely conserved histone H4 N terminus is dispensable for growth but essential for repressing the silent mating loci in yeast

1988 • 441 citations

Histone acetylation reduces nucleosome core particle linking number change

1989 • 394 citations

The structure of DNA in a nucleosome.

1990 • 353 citations

Genetic evidence for an interaction between SIR3 and histone H4 in the repression of the silent mating loci in Saccharomyces cerevisiae.

1990 • 350 citations

Genetic Analysis of Histone H4: Essential Role of Lysines Subject to Reversible Acetylation

1990 • 346 citations

Use of selectively trypsinized nucleosome core particles to analyze the role of the histone “tails” in the stabilization of the nucleosome

1989 • 330 citations

Participation of core histone "tails" in the stabilization of the chromatin solenoid.

1982 • 264 citations

Electrostatic mechanism of chromatin folding

1990 • 259 citations

The regulation of yeast mating-type chromatin structure by SIR: An action at a distance affecting both transcription and transposition

1982 • 257 citations

Physicochemical studies of the folding of the 100 Å nucleosome filament into the 300 Å filament

1986 • 224 citations

Effects of DNA sequence and histone-histone interactions on nucleosome placement

1990 • 188 citations

Notes: Point Mutations in the Yeast Histone H4 Gene Prevent Silencing of the Silent Mating Type Locus HML

1990 • 168 citations

The helical periodicity of DNA on the nucleosome

1981 • 166 citations

Crystallographic Structure of the Octameric Histone Core of the Nucleosome at a Resolution of 3.3 Å

1985 • 155 citations

Patterns of histone acetylation

1990 • 151 citations

Nucleosome linking number change controlled by acetylation of histones H3 and H4.

1990 • 132 citations

A highly basic histone H4 domain bound to the sharply bent region of nucleosomal DNA

1988 • 123 citations

Histone hyperacetylation can induce unfolding of the nucleosome core particle

1990 • 118 citations

Histone acetylation alters the capacity of the H1 histones to condense transcriptionally active/competent chromatin.

1990 • 116 citations

Point mutations in the yeast histone H4 gene prevent silencing of the silent mating type locus HML.

1990 • 108 citations

The Highly Conserved N-Terminal Domains of Histones H3 and H4 Are Required for Normal Cell Cycle Progression

1991 • 96 citations

DNA in the nucleosome

1988 • 92 citations

Yeast histone H2A and H2B amino termini have interchangeable functions

1986 • 88 citations

Chromatin reconstitution on small DNA rings

1988 • 78 citations

Direct detection of linker DNA bending in defined-length oligomers of chromatin.

1990 • 77 citations

Isolation and characterization of acetylated histones H3 and H4 and their assembly into nucleosomes.

1990 • 71 citations

Core histone‐DNA interactions in sea urchin sperm chromatin

1990 • 68 citations

Nucleosome depletion alters the chromatin structure of Saccharomyces cerevisiae centromeres.

1990 • 66 citations

Nucleosome fractionation by mercury affinity chromatography. Contrasting distribution of transcriptionally active DNA sequences and acetylated histones in nucleosome fractions of wild-type yeast cells and cells expressing a histone H3 gene altered to encode a cysteine 110 residue.

1991 • 58 citations

Chromatin reconstitution on small DNA rings

1990 • 57 citations

Chromatin superstructure-dependent crosslinking with DNA of the histone H5 residues Thr1, His25 and His62

1990 • 49 citations

The highly conserved N-terminal domains of histones H3 and H4 are required for normal cell cycle progression.

1991 • 47 citations

Effect of trypsinization and histone H5 addition on DNA twist and topology in reconstituted minichromosomes

1986 • 47 citations

Islands of acetylated histone H4 in polytene chromosomes and their relationship to chromatin packaging and transcriptional activity

1990 • 43 citations

DNA wrapping in nucleosomes. The linking number problem re-examined

1980 • 38 citations

Lysine‐containing DNA‐binding regions on the surface of the histone octamer in the nucleosome core particle

1986 • 35 citations

Spectropolarimetric analysis of the core histone octamer and its subunits

1990 • 26 citations

A NMR study of mobility in the histone octamer

1990 • 22 citations

Crystallization of the globular domain of histone H5

1990 • 22 citations

The histone octamer, a conformationally flexible structure

1987 • 20 citations

Shape Analysis of the Histone Octamer in Solution

1986 • 12 citations

Effect of aggregation of histone octamers in high-salt solutions on circular dichroism spectra

1990 • 5 citations