Excitatory Amino Acid Metabotropic Receptor Subtypes and Calcium Regulation

Inositol trisphosphate and calcium signalling

1993 • 6,546 citations

Inositol trisphosphate, a novel second messenger in cellular signal transduction

1984 • 6,088 citations

Inositol phosphates and cell signalling

1989 • 4,058 citations

Inositol trisphosphate and diacylglycerol as second messengers

1984 • 3,535 citations

Thapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2(+)-ATPase.

1990 • 3,250 citations

Molecular Diversity of Glutamate Receptors and Implications for Brain Function

1992 • 2,535 citations

Molecular cloning and characterization of the rat NMDA receptor

1991 • 1,780 citations

Turnover of Inositol Phospholipids and Signal Transduction

1984 • 1,629 citations

Sequence and expression of a metabotropic glutamate receptor

1991 • 1,200 citations

Long-Term Depression

1989 • 1,151 citations

Intracellular injections of EGTA block induction of hippocampal long-term potentiation

1983 • 1,106 citations

T-cell mitogens cause early changes in cytoplasmic free Ca2+ and membrane potential in lymphocytes

1982 • 1,026 citations

Emptying of intracellular Ca2+ stores releases a novel small messenger that stimulates Ca2+ influx

1993 • 892 citations

A family of metabotropic glutamate receptors

1992 • 873 citations

Postsynaptic Calcium Is Sufficient for Potentiation of Hippocampal Synaptic Transmission

1988 • 830 citations

Glutamate neurotoxicity in cortical cell culture is calcium dependent

1985 • 818 citations

Molecular characterization of a novel metabotropic glutamate receptor mGluR5 coupled to inositol phosphate/Ca2+ signal transduction.

1992 • 814 citations

‘Quanta’ Ca²⁺ release and the control of Ca²⁺ entry by inositol phosphates ‐ a possible mechanism

1990 • 743 citations

Calcium release‐activated calcium current in rat mast cells.

1993 • 729 citations

Molecular characterization of a novel retinal metabotropic glutamate receptor mGluR6 with a high agonist selectivity for L-2-amino-4-phosphonobutyrate

1993 • 724 citations

Synergism of inositol trisphosphate and tetrakisphosphate in activating Ca2+-dependent K+ channels

1987 • 529 citations

Cloning, Expression, and Gene Structure of a G Protein-Coupled Glutamate Receptor from Rat Brain

1991 • 524 citations

Use of Manganese to Discriminate Between Calcium Influx and Mobilization From Internal Stores in Stimulated Human Neutrophils

1989 • 520 citations

Molecular characterization of a new metabotropic glutamate receptor mGluR7 coupled to inhibitory cyclic AMP signal transduction.

1994 • 466 citations

Dynamics of synaptic vesicle fusion and membrane retrieval in synaptic terminals

1994 • 449 citations

Rapid kinetics of second messenger formation in olfactory transduction

1990 • 438 citations

Regulation of NMDA receptor phosphorylation by alternative splicing of the C-terminal domain

1993 • 415 citations

Receptor-activated Ca2+ influx: how many mechanisms for how many channels?

1994 • 403 citations

Depletion of InsP3 stores activates a Ca2+ and K+ current by means of a phosphatase and a diffusible messenger

1993 • 363 citations

Protein kinase C modulation of NMDA currents: an important link for LTP induction

1992 • 350 citations

Calcium-activated non-specific cation channels

1988 • 282 citations

Ca2+ release induced by inositol 1,4,5-trisphosphate is a steady-state phenomenon controlled by luminal Ca2+ in permeabilized cells

1992 • 265 citations

The kinetics of changes in intracellular calcium concentration in fura-2-loaded human platelets.

1987 • 245 citations

Excitatory amino acid antagonists

1991 • 240 citations

Intracellular Ca2+ activates phospholipase C

1988 • 233 citations

Anti-immunoglobulin, cytoplasmic free calcium, and capping in B lymphocytes.

1982 • 223 citations

Ca2+ influx following receptor activation

1991 • 187 citations

Inositol phosphates and Ca ²⁺ entry: toward a proliferation or a simplification?

1992 • 184 citations

Inositol Phospholipid Hydrolysis in Rat Cerebral Cortical Slices: II. Calcium Requirement

1984 • 182 citations

How do inositol phosphates regulate calcium signaling?

1989 • 171 citations

Receptor-activated Ca2+ influx. Two independently regulated mechanisms of influx stimulation coexist in neurosecretory PC12 cells.

1992 • 166 citations

Intracellular injection of Ca2+ chelators blocks induction of long-term depression in rat visual cortex.

1992 • 139 citations

Receptor-activated Ca2+ influx. Two independently regulated mechanisms of influx stimulation coexist in neurosecretory PC12 cells.

1992 • 132 citations

Action potentials must admit calcium to evoke transmitter release

1991 • 115 citations

A new quisqualate receptor subtype (sAA2) responsible for the glutamate-induced inositol phosphate formation in rat brain synaptoneurosomes

1988 • 90 citations

L-glutamate and acetylcholine mobilise Ca2+ from the same intracellular pool in cerebellar granule cells using transduction mechanisms with different Ca2+ sensitivities

1992 • 74 citations

A regulatory calcium-binding site for calcium channel in isolated rat hepatocytes.

1985 • 73 citations

Components of neurite outgrowth that determine neuronal cytoarchitecture: Influence of calcium and the growth substrate

1988 • 65 citations

The role of the metabotropic receptor in synaptic plasticity

1991 • 57 citations

A Specific Trarisduction Mechanism for the Glutamate Action on Phosphoinositide Metabolism via the Quisqualate Metabotropic Receptor in Rat Brain Synaptoneurosomes: I. External Na⁺ Requirement

1991 • 50 citations

Calcium efflux across the plasma membrane of rat parotid acinar cells is unaffected by receptor activation or by the microsomal calcium ATPase inhibitor, thapsigargin

1990 • 47 citations

Developmental changes in the chemosensitivity of rat brain synaptoneurosomes to excitatory amino acids, estimated by inositol phosphate formation

1989 • 37 citations

Differential Regulation of Phosphoinositide Phosphodiesterase Activity in Brain Membranes by Guanine Nucleotides and Calcium

1988 • 28 citations

Ontogenesis of quisqualate‐associated phosphoinositide metabolism in various regions of the rat nervous system

1994 • 16 citations

Effect of Thiol Reagents on Phosphoinositide Hydrolysis in Rat Brain Synaptoneurosomes

1993 • 16 citations

K+ differentially affects the excitatory amino acids- and carbachol-elicited inositol phosphate formation in rat brain synaptoneurosomes

1989 • 13 citations