C terminus of the small GTP-binding protein smg p25A contains two geranylgeranylated cysteine residues and a methyl ester.
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Abstract
References (35)
ras GENES
1987 • 3,818 citations
Rapid analysis of amino acids using pre-column derivatization
1984 • 2,491 citations
All ras proteins are polyisoprenylated but only some are palmitoylated
1989 • 1,806 citations
p21ras is modified by a farnesyl isoprenoid.
1989 • 847 citations
Inhibition of purified p21ras farnesyl:protein transferase by Cys-AAX tetrapeptides
1990 • 815 citations
A Practical Guide to Protein and Peptide Purification for Microsequencing
1993 • 497 citations
rab3 is a small GTP-binding protein exclusively localized to synaptic vesicles.
1990 • 486 citations
Farnesylated γ-subunit of photoreceptor G protein indispensable for GTP-binding
1990 • 389 citations
Posttranslational modification of the Ha-ras oncogene protein: evidence for a third class of protein carboxyl methyltransferases.
1988 • 384 citations
Small GTP-binding proteins in vesicular transport
1990 • 381 citations
Structure of Saccharomyces cerevisiae mating hormone a-factor. Identification of S-farnesyl cysteine as a structural component.
1988 • 373 citations
Farnesol modification of Kirsten-ras exon 4B protein is essential for transformation.
1990 • 333 citations
Human Lamin B Contains a Farnesylated Cysteine Residue
1989 • 324 citations
Purification and characterization from bovine brain cytosol of a protein that inhibits the dissociation of GDP from and the subsequent binding of GTP to smg p25A, a ras p21-like GTP-binding protein.
1990 • 305 citations
Regulation of reversible binding of smg p25A, a ras p21-like GTP-binding protein, to synaptic plasma membranes and vesicles by its specific regulatory protein, GDP dissociation inhibitor.
1990 • 268 citations
A practical guide to protein and peptide purification for microsequencing
1990 • 248 citations
Brain G protein gamma subunits contain an all-trans-geranylgeranylcysteine methyl ester at their carboxyl termini.
1990 • 230 citations
Polyisoprenylation of Ras in vitro by a farnesyl-protein transferase.
1990 • 222 citations
A protein geranylgeranyltransferase from bovine brain: implications for protein prenylation specificity.
1991 • 221 citations
Purification and characterization of a novel GTP-binding protein with a molecular weight of 24,000 from bovine brain membranes.
1988 • 207 citations
Localization and subcellular distribution of smg p25A, a ras p21-like GTP-binding protein, in rat brain.
1990 • 163 citations
Molecular cloning and characterization of a novel type of regulatory protein (GDI) for smg p25A, a ras p21-like GTP-binding protein.
1990 • 161 citations
Posttranslationally processed structure of the human platelet protein smg p21B: evidence for geranylgeranylation and carboxyl methylation of the C-terminal cysteine.
1990 • 151 citations
A carboxyl-terminal cysteine residue is required for palmitic acid binding and biological activity of the ras-related yeast YPT1 protein.
1988 • 138 citations
Identification and preliminary characterization of protein-cysteine farnesyltransferase.
1990 • 138 citations
Peptidal Sex Hormones Inducing Conjugation Tube Formation in Compatible Mating-Type Cells of Tremella mesenterica
1981 • 125 citations
Membrane-binding domain of the small G protein G25K contains an S-(all-trans-geranylgeranyl)cysteine methyl ester at its carboxyl terminus.
1991 • 118 citations
The COOH-terminal domain of the Rap1A (Krev-1) protein is isoprenylated and supports transformation by an H-Ras:Rap1A chimeric protein.
1991 • 109 citations
Regulation of the GTPase activity of the ras-like protein p25rab3A. Evidence for a rab3A-specific GAP.
1991 • 89 citations
Role of the C-terminal region of smg p25A in its interaction with membranes and the GDP/GTP exchange protein.
1991 • 87 citations
Tissue distribution of smg p25A, a ras p21-like GTP-binding protein, studied by use of a specific monoclonal antibody
1989 • 84 citations
A geranylgeranyltransferase for rhoA p21 distinct from the farnesyltransferase for ras p21A
1991 • 68 citations
Molecular Cloning and Characterization of a Novel Type of Regulatory Protein (GDI) for smg p25A, a ras p21-Like GTP-Binding Protein
1990 • 36 citations
The COOH-Terminal Domain of the Rap1A (Krev-1) Protein Is Isoprenylated and Supports Transformation by an H-Ras:Rap1A Chimeric Protein
1991 • 25 citations
Role of the C-Terminal Region of smg p25A in Its Interaction with Membranes and the GDP/GTP Exchange Protein
1991 • 16 citations