Identification of cDNA encoding an additional alpha subunit of a human GTP-binding protein: expression of three alpha i subtypes in human tissues and cell lines.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

G PROTEINS: TRANSDUCERS OF RECEPTOR-GENERATED SIGNALS

1987 • 6,374 citations

A simple and very efficient method for generating cDNA libraries

1983 • 4,606 citations

Efficient isolation of genes by using antibody probes.

1983 • 2,065 citations

Isolation of two proteins with high affinity for guanine nucleotides from membranes of bovine brain.

1984 • 1,300 citations

The βγ subunits of GTP-binding proteins activate the muscarinic K+ channel in heart

1987 • 1,186 citations

Polymorphic DNA region adjacent to the 5' end of the human insulin gene.

1981 • 910 citations

Molecular cloning of five GTP-binding protein cDNA species from rat olfactory neuroepithelium.

1987 • 751 citations

Structure of the GDP Domain of EF-Tu and Location of the Amino Acids Homologous to ras Oncogene Proteins

1985 • 626 citations

Purification and properties of the inhibitory guanine nucleotide regulatory unit of brain adenylate cyclase.

1984 • 585 citations

Inhibition of receptor-mediated release of arachidonic acid by pertussis toxin

1984 • 418 citations

Structural details of the binding of guanosine diphosphate to elongation factor Tu from E. coli as studied by X-ray crystallography.

1985 • 396 citations

Human cDNA clones for four species of G alpha s signal transduction protein.

1986 • 370 citations

Stimulation of phospholipase A2 activity in bovine rod outer segments by the beta gamma subunits of transducin and its inhibition by the alpha subunit.

1987 • 344 citations

Molecular cloning and sequence determination of cDNAs for alpha subunits of the guanine nucleotide-binding proteins Gs, Gi, and Go from rat brain.

1986 • 341 citations

Molecular basis for two forms of the G protein that stimulates adenylate cyclase.

1986 • 319 citations

Primary structure of the α-subunit of transducin and its relationship to ras proteins

1985 • 291 citations

Identification of effector residues and a neutralizing epitope of Ha-ras-encoded p21.

1986 • 291 citations

Sequence of the Alpha Subunit of Photoreceptor G Protein: Homologies Between Transducin, ras , and Elongation Factors

1985 • 276 citations

Identification of Specific Transducin α Subunits in Retinal Rod and Cone Photoreceptors

1986 • 272 citations

Amino acid sequence of the alpha subunit of transducin deduced from the cDNA sequence.

1985 • 202 citations

Family of G protein α chains: amphipathic analysis and predicted structure of functional domains

1986 • 197 citations

Deduced primary structure of the alpha subunit of the GTP-binding stimulatory protein of adenylate cyclase.

1986 • 177 citations

GTPase of bovine rod outer segments: the amino acid sequence of the alpha subunit as derived from the cDNA sequence.

1985 • 169 citations

Inhibitory and stimulatory G proteins of adenylate cyclase: cDNA and amino acid sequences of the alpha chains.

1986 • 159 citations

Primary structure of the α‐subunit of bovine adenylate cyclase‐stimulating G‐protein deduced from the cDNA sequence

1986 • 142 citations

Regional homology in GTP-binding proto-oncogene products and elongation factors.

1983 • 123 citations

Reactive sulfhydryl groups of alpha 39, a guanine nucleotide-binding protein from brain. Location and function.

1987 • 97 citations

Deduced amino acid sequence of bovine retinal Go alpha: similarities to other guanine nucleotide-binding proteins.

1987 • 95 citations

Neuromedins: Novel smooth-muscle stimulating peptides identified in porcine spinal cord

1985 • 91 citations

Human cDNA clones for an alpha subunit of Gi signal-transduction protein.

1987 • 91 citations

Conversion of adrenergic mechanism from an alpha- to a beta-type during primary culture of rat hepatocytes. Accompanying decreases in the function of the inhibitory guanine nucleotide regulatory component of adenylate cyclase identified as the substrate of islet-activating protein.

1984 • 90 citations

Human G_i protein α‐subunit: deduction of amino acid structure from a cloned cDNA

1987 • 85 citations

Molecular cloning of a new human G protein Evidence for two G_iα‐like protein families

1987 • 70 citations

Molecular cloning and characterization of cDNA encoding the GTP-binding protein alpha i and identification of a related protein, alpha h.

1986 • 55 citations

Multiple Control Elements in the TRP1 Promoter of Saccharomyces cerevisiae

1986 • 47 citations

Genes for two homologous G-protein α subunits map to different human chromosomes

1987 • 17 citations

Forensic Scientists Go to Argentina' s Aid

1984 • 2 citations