Identification of Edc3p as an Enhancer of mRNA Decapping inSaccharomyces cerevisiae

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

1994 • 63,397 citations

Basic Local Alignment Search Tool

1990 • 12,947 citations

Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae

1998 • 5,253 citations

Functional organization of the yeast proteome by systematic analysis of protein complexes

2002 • 4,751 citations

A comprehensive analysis of protein–protein interactions in Saccharomyces cerevisiae

2000 • 4,734 citations

Functional profiling of the Saccharomyces cerevisiae genome

2002 • 4,348 citations

Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry

2002 • 3,624 citations

A comprehensive two-hybrid analysis to explore the yeast protein interactome

2001 • 3,564 citations

A network of protein–protein interactions in yeast

2000 • 1,361 citations

Decapping and Decay of Messenger RNA Occur in Cytoplasmic Processing Bodies

2003 • 1,323 citations

Toward a functional analysis of the yeast genome through exhaustive two-hybrid screens

1997 • 886 citations

A turnover pathway for both stable and unstable mRNAs in yeast: evidence for a requirement for deadenylation.

1993 • 660 citations

The 3' to 5' degradation of yeast mRNAs is a general mechanism for mRNA turnover that requires the SKI2 DEVH box protein and 3' to 5' exonucleases of the exosome complex

1998 • 632 citations

The Transcription Factor Associated Ccr4 and Caf1 Proteins Are Components of the Major Cytoplasmic mRNA Deadenylase in Saccharomyces cerevisiae

2001 • 574 citations

Deadenylation of the unstable mRNA encoded by the yeast MFA2 gene leads to decapping followed by 5'-->3' digestion of the transcript.

1994 • 511 citations

Human Dcp2: a catalytically active mRNA decapping enzyme located in specific cytoplasmic structures

2002 • 464 citations

Yeast Sm-like proteins function in mRNA decapping and decay

2000 • 434 citations

A Sm-like protein complex that participates in mRNA degradation

2000 • 390 citations

The human LSm1-7 proteins colocalize with the mRNA-degrading enzymes Dcp1/2 and Xrn1 in distinct cytoplasmic foci

2002 • 387 citations

Yeast cells lacking 5'-->3' exoribonuclease 1 contain mRNA species that are poly(A) deficient and partially lack the 5' cap structure.

1993 • 378 citations

The DCP2 protein is required for mRNA decapping in Saccharomyces cerevisiae and contains a functional MutT motif

1999 • 365 citations

Identification of a Human Decapping Complex Associated with hUpf Proteins in Nonsense-Mediated Decay

2002 • 355 citations

Assessment of prediction accuracy of protein function from protein–protein interaction data

2001 • 354 citations

The DEAD box helicase, Dhh1p, functions in mRNA decapping and interacts with both the decapping and deadenylase complexes

2001 • 342 citations

Turnover Mechanisms of the Stable Yeast PGK1 mRNA

1995 • 341 citations

An essential component of the decapping enzyme required for normal rates of mRNA turnover

1996 • 328 citations

Ccr4p is the catalytic subunit of a Ccr4p/Pop2p/Notp mRNA deadenylase complex inSaccharomyces cerevisiae

2002 • 325 citations

Automated construction and graphical presentation of protein blocks from unaligned sequences

1995 • 321 citations

Stabilization and ribosome association of unspliced pre-mRNAs in a yeast upf1- mutant.

1993 • 265 citations

CCR4, a 3′-5′ poly(A) RNA and ssDNA exonuclease, is the catalytic component of the cytoplasmic deadenylase

2002 • 248 citations

Targeting an mRNA for Decapping

2001 • 233 citations

Mutations affecting stability and deadenylation of the yeast MFA2 transcript.

1992 • 228 citations

Mechanisms of mRNA Surveillance in Eukaryotes

1999 • 212 citations

The yeast POP2 gene encodes a nuclease involved in mRNA deadenylation

2001 • 196 citations

Genome-Wide Protein Interaction Screens Reveal Functional Networks Involving Sm-Like Proteins

2000 • 194 citations

A small segment of the MAT alpha 1 transcript promotes mRNA decay in Saccharomyces cerevisiae: a stimulatory role for rare codons.

1993 • 192 citations

Analysis of recombinant yeast decapping enzyme

2003 • 187 citations

mRNA Decapping in Yeast Requires Dissociation of the Cap Binding Protein, Eukaryotic Translation Initiation Factor 4E

2000 • 184 citations

Function of the Ski4p (Csl4p) and Ski7p Proteins in 3′-to-5′ Degradation of mRNA

2000 • 177 citations

The DEAD box protein Dhh1 stimulates the decapping enzyme Dcp1

2002 • 175 citations

Mutations in trans-Acting Factors Affecting mRNA Decapping in Saccharomyces cerevisiae

1996 • 168 citations

Mechanisms And Control Of mRNA Decapping in Saccharomyces cerevisiae

2000 • 150 citations

The Two Proteins Pat1p (Mrt1p) and Spb8p Interact In Vivo, Are Required for mRNA Decay, and Are Functionally Linked to Pab1p

2000 • 140 citations

Curbing the nonsense: the activation and regulation of mRNA surveillance: Figure 1.

2001 • 105 citations

Two Related Proteins, Edc1p and Edc2p, Stimulate mRNA Decapping in Saccharomyces cerevisiae

2001 • 101 citations

The Yeast Cytoplasmic LsmI/Pat1p Complex Protects mRNA 3′ Termini From Partial Degradation

2001 • 96 citations

The enhancer of decapping proteins, Edc1p and Edc2p, bind RNA and stimulate the activity of the decapping enzyme

2003 • 84 citations

Analysis of Mutations in the Yeast mRNA Decapping Enzyme

1999 • 76 citations

A Small Segment of the MATα1 Transcript Promotes mRNA Decay in Saccharomyces cerevisiae: a Stimulatory Role for Rare Codons

1993 • 63 citations

Temperature-Sensitive Mutations in the Saccharomyces cerevisiae MRT4, GRC5, SLA2 and THS1 Genes Result in Defects in mRNA Turnover

1999 • 55 citations

mRNA turnover in yeast promoted by the MATalpha1 instability element

1996 • 35 citations

Analyzing mRNA decay in saccharomyces cerevisiae

2002 • 17 citations

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