Endothelins in reproduction

A novel potent vasoconstrictor peptide produced by vascular endothelial cells

1988 • 10,786 citations

Cloning and expression of a cDNA encoding an endothelin receptor

1990 • 2,590 citations

The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes.

1989 • 2,551 citations

Cloning of a cDNA encoding a non-isopeptide-selective subtype of the endothelin receptor

1990 • 2,432 citations

Preeclampsia: An endothelial cell disorder

1989 • 1,848 citations

Release of endothelin from the porcine aorta. Inhibition by endothelium-derived nitric oxide.

1990 • 1,066 citations

Endothelin stimulates c‐fos and c‐myc expression and proliferation of vascular smooth muscle cells

1988 • 737 citations

Molecular biology and biochemistry of the endothelins

1989 • 620 citations

Characterization of a coronary vasoconstrictor produced by cultured endothelial cells

1985 • 616 citations

Cloning and sequence analysis of cDNA encoding the precursor of a human endothelium‐derived vasoconstrictor peptide, endothelin: Identity of human and porcine endothelin

1988 • 400 citations

Cloning and functional expression of a vascular smooth muscle endothelin 1 receptor.

1991 • 360 citations

Abundance of endothelin-3 in rat intestine, pituitary gland and brain

1989 • 346 citations

Women with Preeclampsia have Higher Plasma Endothelin Levels than Women with Normal Pregnancies

1990 • 344 citations

Growth factor activity of endothelin on vascular smooth muscle

1990 • 325 citations

Endothelin: A Novel Peptide in the Posterior Pituitary System

1990 • 313 citations

Menstruation in intraocular endometrial transplants in the Rhesus monkey

1978 • 306 citations

Cardiovascular, renal, and endocrine responses to intravenous endothelin in conscious dogs

1988 • 279 citations

Endothelin stimulates phospholipase C in cultured vascular smooth muscle cells

1988 • 241 citations

Endothelin-1-induced vasoconstriction in humans. Reversal by calcium channel blockade but not by nitrovasodilators or endothelium-derived relaxing factor.

1991 • 216 citations

Maternal plasma level of endothelin is increased in preeclampsia

1991 • 203 citations

Endothelial-derived relaxing factor released by endothelial cells of human umbilical vessels and its impairment in pregnancy-induced hypertension

1991 • 189 citations

Autoradiographical Localization of Binding Sites for Porcine [125I]Endothelin-1 in Humans, Pigs, and Rats

1989 • 179 citations

Two distinct types of endothelin receptors are present on chick cardiac membranes

1989 • 176 citations

Endothelin Stimulation of Cytosolic Calcium and Gonadotropin Secretion in Anterior Pituitary Cells

1990 • 172 citations

Phosphoramidon blocks the pressor activity of porcine big endothelin-1-(1-39) in vivo and conversion of big endothelin-1-(1-39) to endothelin-1-(1-21) in vitro.

1991 • 165 citations

Activation of phospholipase A2 by endothelin in cultured vascular smooth muscle cells

1989 • 164 citations

Endothelin-1 mRNA is widely expressed in porcine and human tissues.

1990 • 164 citations

Heterogeneity of cell surface endothelin receptors.

1990 • 159 citations

Similarities in mode and sites of action of sarafotoxins and endothelins

1989 • 152 citations

Endothelin-3 is a novel neuropeptide: Isolation and sequence determination of endothelin-1 and endothelin-3 in porcine brain

1989 • 142 citations

Endothelin is a potent long-lasting vasoconstrictor in men

1989 • 134 citations

Endothelins are more sensitive than sarafotoxins to neutral endopeptidase: possible physiological significance.

1990 • 118 citations

The endothelin peptides ET-1, ET-2, ET-3 and sarafotoxin S6b are co-mitogenic with platelet-derived growth factor for vascular smooth muscle cells

1990 • 118 citations

Two different forms of endothelin receptors in rat lung

1989 • 117 citations

Elimination of Intravenously Injected Endothelin-1 from the Circulation of the Rat

1989 • 112 citations

Endothelin stimulates DNA synthesis in Swiss 3T3 cells. Synergy with polypeptide growth factors

1989 • 98 citations

Effect of endothelin-1 on release of arginine-vasopressin from perifused rat hypothalamus

1989 • 94 citations

Potential role of endothelin-1 in normal and hypertensive pregnancies

1991 • 91 citations

Endothelin induces two types of contractions of rat uterus: Phasic contractions by way of voltage-dependent calcium channels and developing contractions through a second type of calcium channels

1989 • 88 citations

Endothelin increases cytoplasmic calcium and myosin phosphorylation in human myometrium

1990 • 87 citations

Specific receptors for endothelin on membranes from human placenta. Characterization and use in a binding assay

1989 • 82 citations

Immunolocalization, binding, and biological activity of endothelin in rabbit uterus: effect of ovarian steroids

1991 • 76 citations

MORPHOLOGY OF HAEMOSTASIS IN MENSTRUAL ENDOMETRIUM

1980 • 70 citations

Purification and characterization of putative endothelin converting enzyme in bovine adrenal medulla: Evidence for a cathepsin D-like enzyme

1990 • 69 citations

Endothelin receptors in human placenta: relationship to vascular resistance and thromboxane release

1990 • 68 citations

Generation of human endothelin by cathepsin E

1990 • 68 citations

Multiple subtypes of endothelin receptors in porcine tissues: characterization by ligand binding, affinity labeling and regional distribution

1991 • 66 citations

Endothelin-1 gene expression and regulation of endothelin mRNA and protein biosynthesis in avascular human amnion. Potential source of amniotic fluid endothelin.

1991 • 64 citations

Functional endothelin/sarafotoxin receptors in the rat uterus

1989 • 64 citations

Endothelin as an autocrine factor in the regulation of parathyroid cells.

1991 • 62 citations

Expression and regulation of endothelin precursor mRNA m avascular human amnion

1990 • 58 citations

One of the endothelin gene family, endothelin 3 gene, is expressed in the placenta

1990 • 58 citations

Internalization of endothelin by cultured human vascular smooth muscle cells: characterization and physiological significance.

1990 • 57 citations

Immunoreactive endothelin concentrations in maternal and fetal blood

1990 • 57 citations

Increased maternal plasma concentration of endothelin-1 during labor pain or on delivery and the existence of a large amount of endothelin-1 in amniotic fluid

1990 • 56 citations

Localization of immunoreactive endothelin and proendothelin in the human lung

1992 • 55 citations

Regional distribution and pharmacological characterization of [125I] endothelin-1 binding sites in human fetal placental vessels

1991 • 55 citations

NEUROHYPOPHYSEAL HORMONE REGULATION OF ENDOTHELIN SECRETION FROM RABBIT ENDOMETRIAL CELLS IN PRIMARY CULTURE

1990 • 52 citations

Binding Sites for 125I-Labelled Endothelin-1 in the Kidneys: Differential Distribution in Rat, Pig and Man Demonstrated by Using Quantitative Autoradiography

1989 • 49 citations

Endothelin and neuropeptide Y are vasoconstrictors in human uterine blood vessels

1991 • 48 citations

Solubilization and identification of human placental endothelin receptor

1989 • 47 citations

Human placenta expresses endothelin gene and corresponding protein is excreted in urine in increasing amounts during normal pregnancy

1991 • 47 citations

Endothelin-like immunoreactivity in human endometrium

1992 • 44 citations

Preliminary evidence for homoeostatic mechanism regulating endothelin production in pre-eclampsia

1991 • 40 citations

Endothelin-1,2 levels are increased in the amniotic fluid of women with preterm labor and microbial invasion of the amniotic cavity

1992 • 39 citations

Localization and endogenous concentration of endothelin-like immunoreactivity in human placenta

1991 • 39 citations

Binding sites for125I ET-1, ET-2, ET-3 and vasoactive intestinal contractor are present in adult rat brain and neurone-enriched primary cultures of embryonic brain cells

1991 • 36 citations

Binding sites for iodinated endothelin-1, endothelin-2 and endothelin-3 demonstrated on human uterine glandular epithelial cells by quantitative high-resolution autoradiography

1991 • 35 citations

Localization of Endothelin-1 (ET-1), ET-2, and ET-3, Mouse VIC, and Sarafotoxin S6b Binding Sites in Mammalian Heart and Kidney

1991 • 34 citations

Increase in the concentration of immunoreactive endothelin in human pregnancy

1991 • 33 citations

Endothelin production by amnion and its regulation by cytokines

1991 • 32 citations

Different responses to prostaglandin F2α and E2 in human extra- and intramyometrial arteries

1985 • 30 citations

Endothelin-1 stimulates prostaglandin F2α release from human endometrium

1991 • 27 citations

Elevated plasma levels of endothelin in pre-eclampsia

1991 • 25 citations

Endothelins in perinatal biology.

1991 • 24 citations

Native form of endothelin receptor in human placental membranes

1990 • 20 citations

Pressor responsiveness to endothelin is not attenuated in gravid rats

1990 • 15 citations

Endothelin Transfer and Endothelin Effects on Water Transfer in Human Fetal Membranes

1992 • 12 citations

Endothelin in perinatal pharmacology.

1991 • 10 citations

A Prospective Longitudinal Study of Immunoreactive Prostacyclin and Thromboxane Metabolites in Normal and Hypertensive Pregnancy

1985 • 8 citations

94 Endothelin elevation in normal pregnancy and preeclampsia

1991 • 1 citations

93 Endothelin-1 in normal and hypertensive pregnancies

1991 • 1 citations

ほ乳類の心臓及び腎臓におけるエンドセリン-1(ET-1),ET-2,ET-3,マウスVIC及びサラホトキシンS6b結合部位

1991 • 1 citations

97 Plasma immunoreactive endothelin concentrations in severe preeclamptic and normotensive gravidas

1991 • 1 citations