Endothelins are more sensitive than sarafotoxins to neutral endopeptidase: possible physiological significance.

The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes.

1989 • 2,551 citations

Molecular biology and biochemistry of the endothelins

1989 • 620 citations

Neutral endopeptidase 24.11 (enkephalinase) and related regulators of peptide hormones ¹

1989 • 552 citations

Sarafotoxin, a Novel Vasoconstrictor Peptide: Phosphoinositide Hydrolysis in Rat Heart and Brain

1988 • 362 citations

Rat endothelin is a vasodilator in the isolated perfused mesentery of the rat

1989 • 260 citations

A Novel Peptide, Vasoactive Intestinal Contractor, of a New (Endothelin) Peptide Family

1989 • 260 citations

Structure-activity relationships of endothelin: Importance of the C-terminal moiety

1988 • 220 citations

Similarities in mode and sites of action of sarafotoxins and endothelins

1989 • 152 citations

Competitive interaction between endothelin and sarafotoxin: Binding and phosphoinositides hydrolysis in rat atria and brain

1989 • 143 citations

Structure-activity relationship of endothelin: Importance of charged groups

1989 • 120 citations

Three apparent receptor subtypes for the endothelin/sarafotoxin family

1989 • 110 citations

Vascular activities of endothelin‐1 and some alanyl substituted analogues in resistance beds of the rat

1989 • 98 citations

Endothelin - a new family of endothelium-derived peptides with widespread biological properties

1989 • 93 citations

The C-terminal hexapeptide, endothelin-(16–21), discriminates between different endothelin receptors

1989 • 91 citations

SRTX‐d, a new native peptide of the endothelin/sarafotoxin family

1989 • 77 citations

Functional endothelin/sarafotoxin receptors in rat heart myocytes: Structure-activity relationships and receptor subtypes

1989 • 64 citations

¹H‐NMR study of endothelin, sequence‐specific assignment of the spectrum and a solution structure

1989 • 58 citations

Characterization and localization of a novel neuroreceptor for the peptide sarafotoxin

1988 • 52 citations

Investigation of neutral endopeptidases (EC 3.4.24.11) and of neutral proteinases (EC 3.4.24.4) using a new sensitive two‐stage enzymatic reaction

1989 • 43 citations

Disturbances in the cardiovascular system caused by endothelin and sarafotoxin

1989 • 35 citations

Sarafotoxin receptors mediate phosphoinositide hydrolysis in various rat brain regions

1989 • 33 citations

Vasoconstrictor effects of sarafotoxins in rabbit aorta: Structure-function relationships

1989 • 28 citations

Interaction of synthetic sarafotoxin with rat vascular endothelin receptors

1989 • 22 citations

Immunological and structural characterization of sarafotoxin/endothelin family of peptides

1989 • 13 citations