Estrogen and estrogen receptor antagonists stimulate transcription from the human retinoic acid receptor-alpha 1 promoter via a novel sequence.

Identification of a receptor for the morphogen retinoic acid

1987 • 2,007 citations

9-cis retinoic acid is a high affinity ligand for the retinoid X receptor

1992 • 1,790 citations

9-Cis retinoic acid stereoisomer binds and activates the nuclear receptor RXRα

1992 • 1,252 citations

The retinoids—Biology, chemistry and medicine

1996 • 1,192 citations

Function of the retinoic acid receptors (RARs) during development: (II) Multiple abnormalities at various stages of organogenesis in RAR double mutants

1994 • 987 citations

Function of the retinoic acid receptors (RARs) during development: (I) Craniofacial and skeletal abnormalities in RAR double mutants

1994 • 755 citations

Retinoic acid receptors and retinoid X receptors: interactions with endogenous retinoic acids.

1993 • 738 citations

An estrogen-responsive element derived from the 5′ flanking region of the Xenopus vitellogenin A2 gene functions in transfected human cells

1986 • 729 citations

Tamoxifen activation of the estrogen receptor/AP-1 pathway: potential origin for the cell-specific estrogen-like effects of antiestrogens.

1995 • 665 citations

Human estrogen receptor transactivational capacity is determined by both cellular and promoter context and mediated by two functionally distinct intramolecular regions.

1994 • 649 citations

Function of retinoic acid receptor γ in the mouse

1993 • 595 citations

High postnatal lethality and testis degeneration in retinoic acid receptor alpha mutant mice.

1993 • 541 citations

Activation of the ovalbumin gene by the estrogen receptor involves the Fos-Jun complex

1990 • 486 citations

Suppression of Retinoic Acid Receptor–β in Premalignant Oral Lesions and Its Up-Regulation by Isotretinoin

1995 • 419 citations

Hormone receptors: their role in predicting prognosis and response to endocrine therapy.

1978 • 339 citations

Estrogen receptor-Sp1 complexes mediate estrogen-induced cathepsin D gene expression in MCF-7 human breast cancer cells.

1994 • 247 citations

Normal development and growth of mice carrying a targeted disruption of the alpha 1 retinoic acid receptor gene.

1993 • 192 citations

Transactivation properties of retinoic acid and retinoid X receptors in mammalian cells and yeast. Correlation with hormone binding and effects of metabolism.

1993 • 185 citations

Expression and regulation of retinoic acid receptors in human breast cancer cells.

1992 • 143 citations

Targeting expression of a dominant-negative retinoic acid receptor mutant in the epidermis of transgenic mice results in loss of barrier function.

1995 • 137 citations

Ligand-dependent and -independent function of the transactivation regions of the human estrogen receptor in yeast.

1992 • 116 citations

A novel, cell-type-specific mechanism for estrogen receptor-mediated gene activation in the absence of an estrogen-responsive element.

1994 • 97 citations

Retinoid chemoprevention of aerodigestive cancer: From basic research to the clinic

1995 • 95 citations

Monoclonal antibodies to chick intestinal receptors for 1,25-dihydroxyvitamin D3. Interaction and effects of binding on receptor function.

1984 • 91 citations

Estradiol induction of retinoic acid receptors in human breast cancer cells.

1993 • 81 citations

The strategic use of antiestrogens to control the development and growth of breast cancer.

1992 • 77 citations

Retinoic acid receptor α1 isoform is induced by estradiol and confers retinoic acid sensitivity in human breast cancer cells

1995 • 61 citations

Sensitive and specific detection of retinoid receptor subtype proteins in cultured cell and tumor extracts.

1994 • 43 citations

The prevention of adipose differentiation of 3T3-L1 cells caused by retinoic acid is elicited through retinoic acid receptor alpha

1994 • 36 citations

Increased retinoic acid receptor gamma expression suppresses the malignant phenotype and alters the differentiation potential of human neuroblastoma cells.

1995 • 33 citations