Synthetic lethal interactions with conditional poly(A) polymerase alleles identify LCP5, a gene involved in 18S rRNA maturation

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Antibodies, a laboratory manual

1989 • 12,929 citations

Improved tools for biological sequence comparison.

1988 • 11,455 citations

Predicting Coiled Coils from Protein Sequences

1991 • 3,977 citations

Improved method for high efficiency transformation of intact yeast cells

1992 • 3,258 citations

Guide to Yeast Genetics and Molecular Biology

1993 • 2,377 citations

Nuclear targeting sequences — a consensus?

1991 • 1,908 citations

A knowledge base for predicting protein localization sites in eukaryotic cells

1992 • 1,518 citations

2.2 Mb of contiguous nucleotide sequence from chromosome III of C. elegans

1994 • 1,472 citations

The N-end rule: functions, mysteries, uses.

1996 • 859 citations

The cap and poly(A) tail function synergistically to regulate mRNA translational efficiency.

1991 • 795 citations

Use of bacteriophage T7 lysozyme to improve an inducible T7 expression system

1991 • 794 citations

Mechanism and regulation of mRNA polyadenylation

1997 • 762 citations

Starting at the Beginning, Middle, and End: Translation Initiation in Eukaryotes

1997 • 685 citations

Association of the yeast poly(A) tail binding protein with translation initiation factor eIF-4G.

1996 • 679 citations

INTERRELATIONSHIPS OF THE PATHWAYS OF mRNA DECAY AND TRANSLATION IN EUKARYOTIC CELLS

1996 • 653 citations

The poly(A) binding protein is required for poly(A) shortening and 60S ribosomal subunit-dependent translation initiation

1989 • 561 citations

Preparation of Yeast RNA

1993 • 437 citations

A common function for mRNA 5' and 3' ends in translation initiation in yeast.

1995 • 374 citations

Depletion of U3 small nucleolar RNA inhibits cleavage in the 5′ external transcribed spacer of yeast pre-ribosomal RNA and impairs formation of 18S ribosomal RNA.

1991 • 370 citations

The family of box ACA small nucleolar RNAs is defined by an evolutionarily conserved secondary structure and ubiquitous sequence elements essential for RNA accumulation.

1997 • 346 citations

Translation initiation factor eIF4G mediates in vitro poly(A) tail-dependent translation

1997 • 314 citations

A yeast small nuclear RNA is required for normal processing of pre-ribosomal RNA.

1987 • 313 citations

A yeast nucleolar protein related to mammalian fibrillarin is associated with small nucleolar RNA and is essential for viability.

1989 • 310 citations

Multiple functions for the poly(A)-binding protein in mRNA decapping and deadenylation in yeast.

1995 • 278 citations

Depletion of U14 small nuclear RNA (snR128) disrupts production of 18S rRNA in Saccharomyces cerevisiae.

1990 • 272 citations

A Review of Phenotypes in Saccharomyces cerevisiae

1997 • 270 citations

Functional Analysis of the Genes of Yeast Chromosome V by Genetic Footprinting

1996 • 268 citations

Accurate Processing of a Eukaryotic Precursor Ribosomal RNA by Ribonuclease MRP in Vitro

1996 • 265 citations

From nucleoporins to nuclear pore complexes

1997 • 243 citations

eIF4G Dramatically Enhances the Binding of eIF4E to the mRNA 5′-Cap Structure

1997 • 235 citations

Phenotypic suppression and misreading in Saccharomyces cerevisiae

1979 • 235 citations

Synthetic enhancement in gene interaction: a genetic tool come of age

1993 • 234 citations

Phenotypic suppression of nonsense mutants in yeast by aminoglycoside antibiotics

1979 • 231 citations

MIPS: a database for protein sequences, homology data and yeast genome information

1997 • 231 citations

RNase III Cleaves Eukaryotic Preribosomal RNA at a U3 snoRNP-Dependent Site

1996 • 230 citations

Hrp1, a sequence-specific RNA-binding protein that shuttles between the nucleus and the cytoplasm, is required for mRNA 3′-end formation in yeast

1997 • 225 citations

Base pairing between U3 and the pre-ribosomal RNA is required for 18S rRNA synthesis.

1995 • 224 citations

Poly(A) tail metabolism and function in eucaryotes.

1993 • 213 citations

Yeast snR30 Is a Small Nucleolar RNA Required for 18S rRNA Synthesis

1993 • 212 citations

Processing of pre‐ribosomal RNA in Saccharomyces cerevisiae

1995 • 210 citations

The 3' end of yeast 5.8S rRNA is generated by an exonuclease processing mechanism.

1996 • 208 citations

Mutational analysis of mammalian poly(A) polymerase identifies a region for primer binding and catalytic domain, homologous to the family X polymerases, and to other nucleotidyltransferases.

1996 • 189 citations

The biochemistry of polyadenylation

1996 • 186 citations

GENETIC ANALYSIS OF THE YEAST CYTOSKELETON

1987 • 179 citations

RNA14 and RNA15 Proteins as Components of a Yeast Pre-mRNA 3′-End Processing Factor

1994 • 161 citations

The major yeast poly(A)-binding protein is associated with cleavage factor IA and functions in premessenger RNA 3′-end formation

1997 • 161 citations

Fal1p Is an Essential DEAD-Box Protein Involved in 40S-Ribosomal-Subunit Biogenesis in Saccharomyces cerevisiae

1997 • 159 citations

No end yet to messenger RNA 3′ processing!

1995 • 153 citations

RRP5 is required for formation of both 18S and 5.8S rRNA in yeast.

1996 • 149 citations

The FIP1 gene encodes a component of a yeast pre-mRNA polyadenylation factor that directly interacts with poly(A) polymerase

1995 • 136 citations

NSR1 Is Required for Pre-rRNA Processing and for the Proper Maintenance of Steady-State Levels of Ribosomal Subunits

1992 • 131 citations

A comparison of mammalian and yeast pre-mRNA 3′-end processing

1997 • 122 citations

A U3 snoRNP protein with homology to splicing factor PRP4 and G beta domains is required for ribosomal RNA processing.

1993 • 118 citations

Mpp10p, a U3 Small Nucleolar Ribonucleoprotein Component Required for Pre-18S rRNA Processing in Yeast

1997 • 112 citations

Sequence Similarity Between the 73-Kilodalton Protein of Mammalian CPSF and a Subunit of Yeast Polyadenylation Factor I

1996 • 105 citations

Depletion of U14 Small Nuclear RNA (snR128) Disrupts Production of 18S rRNA in Saccharomyces cerevisiae

1990 • 105 citations

Poly(A) binds to initiation factors and increases cap-dependent translation in vitro.

1994 • 101 citations

Synthetic lethal mutations suggest interactions between U5 small nuclear RNA and four proteins required for the second step of splicing.

1992 • 98 citations

Purification of the Saccharomyces cerevisiae Cleavage/Polyadenylation Factor I

1996 • 89 citations

A multisubunit 3' end processing factor from yeast containing poly(A) polymerase and homologues of the subunits of mammalian cleavage and polyadenylation specificity factor

1997 • 89 citations

Mechanisms of action of aminoglycoside antibiotics in eucaryotic protein synthesis

1984 • 82 citations

Transcriptional Activation by Yeast PDR1p Is Inhibited by Its Association with NGG1p/ADA3p

1996 • 65 citations

Construction of a Yeast Strain Deleted for theTRP1 Promoter and Coding Region that Enhances the Efficiency of the Polymerase Chain Reaction-Disruption Method

1997 • 63 citations

Cleavage Factor II of Saccharomyces cerevisiaeContains Homologues to Subunits of the Mammalian Cleavage/ Polyadenylation Specificity Factor and Exhibits Sequence-specific, ATP-dependent Interaction with Precursor RNA

1997 • 60 citations

Fidelity of the eukaryotic codon-anticodon interaction: interference by aminoglycoside antibiotics

1984 • 58 citations

Processing of the yeast pre-rRNA at sites A(2) and A(3) is linked.

1996 • 45 citations

Ribosome Concentration Contributes to Discrimination against Poly(A)− mRNA during Translation Initiation in Saccharomyces cerevisiae

1997 • 37 citations