Early acquisition, but not retention, of the classically conditioned eyeblink response is N-methyl-D-aspartate (NMDA) receptor dependent.
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References (60)
The organization of behavior
1988 • 8,668 citations
Long‐lasting potentiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant path
1973 • 7,118 citations
Selective impairment of learning and blockade of long-term potentiation by an N-methyl-D-aspartate receptor antagonist, AP5
1986 • 3,586 citations
Excitatory amino acids in synaptic transmission in the Schaffer collateral‐commissural pathway of the rat hippocampus.
1983 • 2,376 citations
Different projections of the central amygdaloid nucleus mediate autonomic and behavioral correlates of conditioned fear
1988 • 1,573 citations
Two-process learning theory: Relationships between Pavlovian conditioning and instrumental learning.
1967 • 1,474 citations
Integrative activity of the brain
1967 • 1,388 citations
Distribution of N-methyl-D-aspartate-sensitive L-[3H]glutamate-binding sites in rat brain
1985 • 1,294 citations
The lateral amygdaloid nucleus: sensory interface of the amygdala in fear conditioning
1990 • 1,134 citations
The Biochemistry of Memory: A New and Specific Hypothesis
1984 • 1,048 citations
Synaptic plasticity and learning: selective impairment of learning rats and blockade of long-term potentiation in vivo by the N-methyl-D- aspartate receptor antagonist AP5
1989 • 766 citations
Extinction of fear-potentiated startle: blockade by infusion of an NMDA antagonist into the amygdala
1992 • 682 citations
Hippocampectomy disrupts trace eye-blink conditioning in rabbits.
2015 • 673 citations
Hippocampus and trace conditioning of the rabbit's classically conditioned nictitating membrane response.
1986 • 671 citations
Distinct components of spatial learning revealed by prior training and NMDA receptor blockade
1995 • 560 citations
The NMDA receptor antagonist D-2-amino-5-phosphonopentanoate (D-AP5) impairs spatial learning and LTP in vivo at intracerebral concentrations comparable to those that block LTP in vitro
1992 • 545 citations
Neuronal Substrate of Classical Conditioning in the Hippocampus
1976 • 523 citations
Contributions of Quisqualate and NMDA Receptors to the Induction and Expression of LTP
1988 • 512 citations
Synaptic plasticity in the basolateral amygdala induced by hippocampal formation stimulation in vivo
1995 • 496 citations
Initial localization of the memory trace for a basic form of learning.
1982 • 332 citations
Facilitation of glutamate receptors enhances memory.
1994 • 331 citations
Spatial learning without NMDA receptor-dependent long-term potentiation
1995 • 326 citations
Hippocampectomy selectively disrupts discrimination reversal conditioning of the rabbit nictitating membrane response
1983 • 324 citations
Stress-Induced Facilitation of Classical Conditioning
1992 • 312 citations
Synaptic plasticity in fear conditioning circuits: induction of LTP in the lateral nucleus of the amygdala by stimulation of the medial geniculate body
1990 • 310 citations
The amygdala complex: multiple roles in associative learning and attention.
1994 • 300 citations
N-methyl-D-aspartate receptor antagonist APV blocks acquisition but not expression of fear conditioning.
1991 • 290 citations
N‐methyl aspartate activates voltage‐dependent calcium conductance in rat hippocampal pyramidal cells.
1983 • 281 citations
Intra-amygdala infusion of the N-methyl-D-aspartate receptor antagonist AP5 blocks acquisition but not expression of fear-potentiated startle to an auditory conditioned stimulus.
1992 • 256 citations
NMDA processes mediate anterograde amnesia of contextual fear conditioning induced by hippocampal damage: Immunization against amnesia by context preexposure.
1994 • 229 citations
Current Topics in Animal Learning
2013 • 222 citations
Antagonism of NMDA receptors impairs acquisition but not retention of olfactory memory.
1989 • 210 citations
Behavioral effects of MK-801 mimic deficits associated with hippocampal damage
1989 • 190 citations
CGP 37849 and CGP 39551: novel and potent competitive N‐methyl‐<scp>d</scp>‐aspartate receptor antagonists with oral activity
1990 • 186 citations
NMDA antagonist MK-801 impairs acquisition but not performance of spatial working and reference memory
1990 • 170 citations
Fear-potentiated startle using an auditory conditioned stimulus: Effect of lesions of the amygdala
1987 • 160 citations
Immediate and long-lasting effects of MK-801 on motor activity, spatial navigation in a swimming pool and EEG in the rat
1989 • 159 citations
Effects of intra-amygdala injections of NMDA receptor antagonists on acquisition and retention of inhibitory avoidance
1992 • 142 citations
Bilateral cerebellar lesions disrupt conditioned eyelid responses in unrestrained rats.
1988 • 138 citations
Hippocampal lesions impair memory of short-delay conditioned eye blink in rabbits.
1989 • 137 citations
Why NMDA-receptor-dependent long-term potentiation may not be a mechanism of learning and memory: Reappraisal of the NMDA-receptor blockade strategy
1990 • 129 citations
Cerebellar long-term potentiation under suppressed postsynaptic Ca2+ activity
1992 • 126 citations
Effects of stress and long-term potentiation (LTP) on subsequent LTP and the theta burst response in the dentate gyrus
1994 • 115 citations
Long-term potentiation in the interpositus and vestibular nuclei in the rat
1986 • 112 citations
A centrally active drug that modulates AMPA receptor gated currents
1994 • 111 citations
Hyperactivity, hyper-reactivity, and sensorimotor deficits induced by low doses of the N-methyl-d-aspartate non-competitive channel blocker MK801
1992 • 103 citations
Exposure to inescapable stress persistently facilitates associative and nonassociative learning in rats.
1994 • 99 citations
Effects of amygdala lesions on reflex facilitation and conditioned response acquisition during nictitating membrane response conditioning in rabbit.
1992 • 99 citations
Experimentally acquired drives.
1948 • 70 citations
CS Intensity effects on rabbit nictitating membrane conditioning, extinction and generalization
1974 • 56 citations
The Neural Basis of Behavior
1982 • 55 citations
Stress-induced sensitization and facilitated learning require NMDA receptor activation
1995 • 54 citations
Enhanced glutamatergic neurotransmission facilitates classical conditioning in the freely moving rat
1995 • 51 citations
Effects of MK-801 on learning and memory as assessed using a novel water maze
1991 • 49 citations
Effects of Conditioned Arousal on the Auditory System
1982 • 42 citations
Intracerebral distribution of DL-2-amino-phosphonopentanoic acid (AP5) and the dissociation of different types of learning
1991 • 41 citations
Stress impedes exploration and the acquisition of spatial information in the eight-arm radial maze
1992 • 35 citations
Effects of the novel NMDA receptor antagonist, CGP 39551, on field potentials and the induction and expression of LTP in the dentate gyrus in vivo
1992 • 23 citations
MK801 retards acquisition of a classically conditioned response without affecting conditioning-related alterations in perforant path-granule cell synaptic transmission
1993 • 22 citations
It’s heads they win, tails I lose!
1990 • 16 citations