A new Drosophila spliceosomal intron position is common in plants

The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools

1997 • 38,984 citations

Exonic splicing enhancers: mechanism of action, diversity and role in human genetic diseases

2000 • 689 citations

On the Possibility of Constructive Neutral Evolution

1999 • 502 citations

Evolution of the proteases of blood coagulation and fibrinolysis by assembly from modules

1985 • 492 citations

Pseudogenes in yeast?

1987 • 316 citations

Intron evolution as a population-genetic process

2002 • 276 citations

"Five Easy Pieces"

1991 • 255 citations

Evidence that introns arose at proto-splice sites.

1989 • 235 citations

The recent origins of spliceosomal introns revisited

1998 • 204 citations

Large-scale comparison of intron positions among animal, plant, and fungal genes

2002 • 191 citations

The evolution of spliceosomal introns

2002 • 162 citations

Intron “sliding” and the diversity of intron positions

1997 • 156 citations

A spliceosomal intron in Giardia lamblia

2002 • 156 citations

The Large srh Family of Chemoreceptor Genes in Caenorhabditis Nematodes Reveals Processes of Genome Evolution Involving Large Duplications and Deletions and Intron Gains and Losses

2000 • 148 citations

Evolution of Intron/Exon Structure of DEAD Helicase Family Genes in Arabidopsis, Caenorhabditis, and Drosophila

2001 • 139 citations

Intron sliding in conserved gene families

2000 • 117 citations

Widespread Occurrence of Spliceosomal Introns in the rDNA Genes of Ascomycetes

2000 • 112 citations

Molecular evolution: Recent cases of spliceosomal intron gain?

1998 • 110 citations

Signatures of Domain Shuffling in the Human Genome

2002 • 101 citations

Shared Nucleotide Composition Biases Among Species and Their Impact on Phylogenetic Reconstructions of the Drosophilidae

2001 • 98 citations

A variable intron distribution in globin genes of Chironomus: evidence for recent intron gain

1997 • 96 citations

Association of intron phases with conservation at splice site sequences and evolution of spliceosomal introns

1999 • 95 citations

Tree Rooting with Outgroups When They Differ in Their Nucleotide Composition from the Ingroup: The Drosophila saltans and willistoni Groups, a Case Study

2000 • 73 citations

Exon/intron structure of aldehyde dehydrogenase genes supports the “ introns-late ” theory

1997 • 69 citations

Erratic overdispersion of three molecular clocks: GPDH, SOD, and XDH

2001 • 67 citations

New Drosophila introns originate by duplication

1998 • 55 citations

Switch in Codon Bias and Increased Rates of Amino Acid Substitution in the Drosophila saltans Species Group

1999 • 51 citations

Fluctuating Mutation Bias and the Evolution of Base Composition in Drosophila

2000 • 48 citations

Module–intron correlation and intron sliding in family F/10 xylanase genes

1999 • 43 citations

Centripetal modules and ancient introns

1999 • 42 citations

Molecular Evolution and Phylogeny of the buzzatii Complex (Drosophila repleta Group): A Maximum-Likelihood Approach

2000 • 40 citations

Evidence for a High Ancestral GC Content in Drosophila

2000 • 36 citations

Nucleosome formation potential of exons, introns, and Alu repeats

2001 • 23 citations

Molecular Population Genetics of Xdh and the Evolution of Base Composition in Drosophila

2002 • 23 citations

Generation of a database containing discordant intron positions in eukaryotic genes (MIDB)

2001 • 21 citations

Disparate Evolution of Paralogous Introns in the Xdh Gene of Drosophila

2000 • 11 citations