Induction of transforming growth factor beta 1 resistance by the E1A oncogene requires binding to a specific set of cellular proteins.

The Human Papilloma Virus-16 E7 Oncoprotein Is Able to Bind to the Retinoblastoma Gene Product

1989 • 3,036 citations

Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter.

1982 • 2,753 citations

Transforming growth factor beta

2011 • 1,990 citations

Association between an oncogene and an anti-oncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product

1988 • 1,440 citations

Adenovirus early region 1A enables viral and cellular transforming genes to transform primary cells in culture

1983 • 1,358 citations

Monoclonal antibodies specific for simian virus 40 tumor antigens

1981 • 1,110 citations

TGF-β stimulation and inhibition of cell proliferation: New mechanistic insights

1990 • 992 citations

Oncogenes, antioncogenes, and the molecular bases of multistep carcinogenesis.

1989 • 961 citations

Growth inhibition by TGF-β linked to suppression of retinoblastoma protein phosphorylation

1990 • 812 citations

Cellular targets for transformation by the adenovirus E1A proteins

1989 • 747 citations

Human cyclin A is adenovirus E1A-associated protein p60 and behaves differently from cyclin B

1990 • 730 citations

The retinoblastoma susceptibility gene encodes a nuclear phosphoprotein associated with DNA binding activity

1987 • 649 citations

TGF-β1 inhibition of c-myc transcription and growth in keratinocytes is abrogated by viral transforming proteins with pRB binding domains

1990 • 612 citations

Type beta transforming growth factor is the primary differentiation-inducing serum factor for normal human bronchial epithelial cells.

1986 • 570 citations

Reversible inhibition of normal human prokeratinocyte proliferation by type beta transforming growth factor-growth inhibitor in serum-free medium.

1986 • 559 citations

Monoclonal antibodies specific for adenovirus early region 1A proteins: extensive heterogeneity in early region 1A products

1985 • 417 citations

Multiple functional domains in the adenovirus E1A gene

1987 • 361 citations

Absence of TGF-β Receptors and Growth Inhibitory Responses in Retinoblastoma Cells

1988 • 331 citations

Transforming growth factor-β inhibition of epithelial cell proliferation linked to the expression of a 53-kDa membrane receptor

1989 • 325 citations

A survey of transformation markers in differentiating epidermal cell lines in culture.

1980 • 320 citations

Comparison of the in vitro transforming activities of human papillomavirus types.

1988 • 303 citations

Functional domains of adenovirus type 5 E1a proteins

1987 • 283 citations

Localized production of TGF-β mRNA in tumour promoter-stimulated mouse epidermis

1988 • 275 citations

A 60 kd cdc2-associated polypeptide complexes with the E1A proteins in adenovirus-infected cells

1989 • 262 citations

Growth modulation of mouse keratinocytes by transforming growth factors.

1988 • 242 citations

Two regions of the adenovirus early region 1A proteins are required for transformation

1988 • 232 citations

Retinoblastoma growth suppressor and a 300-kDa protein appear to regulate cellular DNA synthesis.

1990 • 209 citations

Transformation of murine melanocytes by basic fibroblast growth factor cDNA and oncogenes and selective suppression of the transformed phenotype in a reconstituted cutaneous environment.

1989 • 146 citations

[17] Identification of receptor for type-β transforming growth factor

1987 • 134 citations

Regulation of growth and differentiation of human keratinocytes by type beta transforming growth factor and epidermal growth factor.

1987 • 124 citations

Transforming growth factors beta 1 and 2 transcriptionally regulate human papillomavirus (HPV) type 16 early gene expression in HPV-immortalized human genital epithelial cells

1990 • 123 citations

Malignant transformation of mouse primary keratinocytes by Harvey sarcoma virus and its modulation by surrounding normal cells.

1988 • 118 citations

Long terminal repeat sequences impart hematopoietic transformation properties to the myeloproliferative sarcoma virus.

1985 • 110 citations

Differential response of nontumorigenic and tumorigenic human papillomavirus type 16-positive epithelial cells to transforming growth factor beta 1.

1990 • 87 citations

Tyrosine phosphorylation is an early and specific event involved in primary keratinocyte differentiation.

1990 • 77 citations

A retrovirus expressing the 12S adenoviral E1A gene product can immortalize epithelial cells from a broad range of rat tissues.

1988 • 64 citations

Environment‐dependent growth inhibition of human epidermal keratinocytes by recombinant human transforming growth factor‐beta

1989 • 54 citations

Expression of HLA-DR antigen in human class II mutant B-cell lines by double infection with retrovirus vectors.

1987 • 31 citations

Tyrosine Phosphorylation Is an Early and Specific Event Involved in Primary Keratinocyte Differentiation

1990 • 19 citations

A retrovirus Expressing the 12S Adenoviral E1A Gene Product Can Immortalize Epithelial Cells from a Broad Range of Rat Tissues

1988 • 18 citations

Transcriptional Activation of the c-myc Proto-Oncogene in Murine Keratinocytes Enhances the Response to Epidermal Growth Factor

1989 • 14 citations

Expression of HLA-DR antigen in human class II mutant B-cell lines by double infection with retrovirus vectors

1987 • 12 citations