RICK/Rip2/CARDIAK mediates signalling for receptors of the innate and adaptive immune systems

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

1998 • 7,541 citations

A Toll-like receptor recognizes bacterial DNA

2000 • 6,348 citations

Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3

2001 • 5,893 citations

Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

2001 • 5,526 citations

A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

2001 • 4,997 citations

Differential Roles of TLR2 and TLR4 in Recognition of Gram-Negative and Gram-Positive Bacterial Cell Wall Components

1999 • 3,351 citations

Unresponsiveness of MyD88-Deficient Mice to Endotoxin

1999 • 2,088 citations

MyD88 Is an Adaptor Protein in the hToll/IL-1 Receptor Family Signaling Pathways

1998 • 1,565 citations

Innate immune recognition: mechanisms and pathways

2000 • 1,451 citations

Nod2, a Nod1/Apaf-1 Family Member That Is Restricted to Monocytes and Activates NF-κB

2001 • 1,331 citations

The Death Domain Kinase RIP Mediates the TNF-Induced NF-κB Signal

1998 • 1,062 citations

CARD15 mutations in Blau syndrome

2001 • 945 citations

PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes

2000 • 890 citations

Nod1, an Apaf-1-like Activator of Caspase-9 and Nuclear Factor-κB

1999 • 725 citations

CARD4/Nod1 mediates NF‐κB and JNK activation by invasive Shigella flexneri

2001 • 588 citations

Bcl10 Is a Positive Regulator of Antigen Receptor–Induced Activation of NF-κ B and Neural Tube Closure

2001 • 551 citations

Human Nod1 Confers Responsiveness to Bacterial Lipopolysaccharides

2001 • 534 citations

Evidence for a gamma-interferon receptor that regulates macrophage tumoricidal activity.

1984 • 471 citations

RIP2 Is a Novel NF-κB-activating and Cell Death-inducing Kinase

1998 • 425 citations

Human CARD4 Protein Is a Novel CED-4/Apaf-1 Cell Death Family Member That Activates NF-κB

1999 • 363 citations

Identification of CARDIAK, a RIP-like kinase that associates with caspase-1

1998 • 316 citations

ICEBERG

2000 • 267 citations

Expression of a murine homologue of the inhibitor of apoptosis protein is related to cell proliferation

1999 • 251 citations

IL-18–stimulated GADD45β required in cytokine-induced, but not TCR-induced, IFN-γ production

2001 • 237 citations

RICK, a Novel Protein Kinase Containing a Caspase Recruitment Domain, Interacts with CLARP and Regulates CD95-mediated Apoptosis

1998 • 232 citations

Preferential role for NF-kappa B/Rel signaling in the type 1 but not type 2 T cell-dependent immune response in vivo.

1999 • 167 citations

Preferential Role for NF-κB/Rel Signaling in the Type 1 But Not Type 2 T Cell-Dependent Immune Response In Vivo

1999 • 146 citations

Regulation of naive T cell differentiation by varying the potency of TCR signal transduction

1999 • 102 citations

High-resolution Genetic and Physical Map of theLgn1Interval in C57BL/6J ImplicatesNaip2orNaip5inLegionella pneumophilaPathogenesis

2000 • 61 citations

Differential regulation of cytokine and cytokine receptor mRNA expression upon infection of bone marrow-derived macrophages with Listeria monocytogenes

1996 • 47 citations