The Salmonella typhimurium tyrosine phosphatase SptP is translocated into host cells and disrupts the actin cytoskeleton

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

1992 • 4,454 citations

Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

1995 • 4,387 citations

Aromatic-dependent Salmonella typhimurium are non-virulent and effective as live vaccines

1981 • 2,042 citations

Eukaryotic proteins expressed in Escherichia coli: An improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase

1991 • 1,779 citations

Target cell contact triggers expression and polarized transfer of Yersinia YopE cytotoxin into mammalian cells.

1994 • 594 citations

Molecular and functional characterization of the Salmonella invasion gene invA: homology of InvA to members of a new protein family

1992 • 578 citations

Translocation of a hybrid YopE‐adenylate cyclase from Yersinia enterocolitica into HeLa cells

1994 • 532 citations

Molecular genetic bases of Salmonella entry into host cells

1996 • 432 citations

Secretion of Yop proteins by Yersiniae

1990 • 407 citations

Salmonella spp. are cytotoxic for cultured macrophages

1996 • 379 citations

Intracellular targeting of the Yersinia YopE cytotoxin in mammalian cells induces actin microfilament disruption

1991 • 376 citations

Cytoskeletal rearrangements accompanying Salmonella entry into epithelial cells

1991 • 349 citations

Requirement of CDC42 for Salmonella -Induced Cytoskeletal and Nuclear Responses

1996 • 303 citations

The invasion‐associated type III system of Salmonella typhimurium directs the translocation of Sip proteins into the host cell

1997 • 300 citations

Expression of Salmonella typhimurium genes required for invasion is regulated by changes in DNA supercoiling

1990 • 296 citations

Homologs of the Shigella IpaB and IpaC invasins are required for Salmonella typhimurium entry into cultured epithelial cells

1995 • 279 citations

Exoenzyme S of Pseudomonas aeruginosa is secreted by a type III pathway

1996 • 272 citations

Cell‐surface‐bound Yersinia translocate the protein tyrosine phosphatase YopH by a polarized mechanism into the target cell

1995 • 246 citations

A secreted protein tyrosine phosphatase with modular effector domains in the bacterial pathogen Salmonella typhimurlum

1996 • 240 citations

SopE, a secreted protein of Salmonelladublin, is translocated into the target eukaryotic cell via a sip‐dependent mechanism and promotes bacterial entry

1996 • 240 citations

Identification of two targets of the type III protein secretion system encoded by the inv and spa loci of Salmonella typhimurium that have homology to the Shigella IpaD and IpaA proteins

1995 • 227 citations

A secreted Salmonella protein with homology to an avirulence determinant of plant pathogenic bacteria

1997 • 218 citations

Identification and molecular characterization of a Salmonella typhimurium gene involved in triggering the internalization of salmonellae into cultured epithelial cells.

1992 • 197 citations

The plasmid‐encoded Yop2b protein of Yersinia pseudotuberculosis is a virulence determinant regulated by calcium and temperature at the level of transcription

1988 • 172 citations

CROSS-TALK BETWEEN BACTERIAL PATHOGENS AND THEIR HOST CELLS

1996 • 153 citations

Requirement for exported proteins in secretion through the invasion-associated type III system of Salmonella typhimurium

1996 • 152 citations

Functional analysis of the Salmonella typhimurium invasion genes invl and invJ and identification of a target of the protein secretion apparatus encoded in the inv locus

1995 • 135 citations

Salmonella typhimurium secreted invasion determinants are homologous to Shigella lpa proteins

1995 • 134 citations

Characterization of Pseudomonas aeruginosa-induced MDCK cell injury: glycosylation-defective host cells are resistant to bacterial killing

1995 • 105 citations

Cloning the structural gene for the 49-kDa form of exoenzyme S (exoS) from Pseudomonas aeruginosa strain 388.

1994 • 95 citations

Genetic analysis of the yopE region of Yersinia spp.: identification of a novel conserved locus, yerA, regulating yopE expression

1990 • 83 citations

Nucleotide sequence and transcription analysis of yop51 from Yersinia enterocolitica W22703

1988 • 77 citations

Simultaneous analysis of purines, pyrimidines, and amino acids

1969 • 19 citations