Essential Requirement of BMPs-2/4 for Both Osteoblast and Osteoclast Formation in Murine Bone Marrow Cultures from Adult Mice: Antagonism by Noggin

Osteoprotegerin Ligand Is a Cytokine that Regulates Osteoclast Differentiation and Activation

1998 • 5,369 citations

Osf2/Cbfa1: A Transcriptional Activator of Osteoblast Differentiation

1997 • 4,191 citations

Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL

1998 • 4,184 citations

Targeted Disruption of Results in a Complete Lack of Bone Formation owing to Maturational Arrest of Osteoblasts

1997 • 4,168 citations

Inhibition of osteoblastogenesis and promotion of apoptosis of osteoblasts and osteocytes by glucocorticoids. Potential mechanisms of their deleterious effects on bone.

1998 • 1,705 citations

Bone Marrow, Cytokines, and Bone Remodeling — Emerging Insights into the Pathophysiology of Osteoporosis

1995 • 1,661 citations

The Spemann Organizer Signal noggin Binds and Inactivates Bone Morphogenetic Protein 4

1996 • 1,604 citations

Bone morphogenetic protein-2 converts the differentiation pathway of C2C12 myoblasts into the osteoblast lineage [published erratum appears in J Cell Biol 1995 Feb;128(4):following 713]

1994 • 1,442 citations

Increased Osteoclast Development After Estrogen Loss: Mediation by Interleukin-6

1992 • 1,437 citations

Principles of Bone Biology

1997 • 1,367 citations

Dorsoventral Patterning in Xenopus: Inhibition of Ventral Signals by Direct Binding of Chordin to BMP-4

1996 • 1,126 citations

Modulation of Osteoclast Differentiation

1992 • 1,014 citations

Osteonal and hemi‐osteonal remodeling: The spatial and temporal framework for signal traffic in adult human bone

1994 • 968 citations

Noggin, Cartilage Morphogenesis, and Joint Formation in the Mammalian Skeleton

1998 • 810 citations

Estrogen promotes apoptosis of murine osteoclasts mediated by TGF–β

1996 • 799 citations

Cerberus is a head-inducing secreted factor expressed in the anterior endoderm of Spemann's organizer

1996 • 757 citations

RANK Is the Essential Signaling Receptor for Osteoclast Differentiation Factor in Osteoclastogenesis

1998 • 729 citations

Inhibition of Osf2/Cbfa1 expression and terminal osteoblast differentiation by PPARgamma2.

1999 • 463 citations

Inhibition of Osf2/Cbfa1 expression and terminal osteoblast differentiation by PPAR?2

1999 • 395 citations

Linkage of decreased bone mass with impaired osteoblastogenesis in a murine model of accelerated senescence.

1996 • 345 citations

Bone morphogenetic proteins induce the expression of noggin, which limits their activity in cultured rat osteoblasts.

1998 • 339 citations

Smad5 and DPC4 Are Key Molecules in Mediating BMP-2-induced Osteoblastic Differentiation of the Pluripotent Mesenchymal Precursor Cell Line C2C12

1998 • 319 citations

The Xenopus Dorsalizing Factor noggin Ventralizes Drosophila Embryos by Preventing DPP from Activating Its Receptor

1996 • 242 citations

Stimulatory effect of bone morphogenetic protein-2 on osteoclast-like cell formation and bone-resorbing activity

1995 • 229 citations

Loss of estrogen upregulates osteoblastogenesis in the murine bone marrow. Evidence for autonomy from factors released during bone resorption.

1998 • 215 citations

Competition between noggin and bone morphogenetic protein 4 activities may regulate dorsalization during Xenopus development.

1995 • 161 citations

Identification of mammalian noggin and its expression in the adult nervous system

1995 • 135 citations

Regulation of the gp80 and gp130 subunits of the IL-6 receptor by sex steroids in the murine bone marrow.

1997 • 129 citations

The Effects of Androgen Deficiency on Murine Bone Remodeling and Bone Mineral Density Are Mediated via Cells of the Osteoblastic Lineage*

1997 • 125 citations

Osteopontin Expression by Osteoclast and Osteoblast Progenitors in the Murine Bone Marrow: Demonstration of Its Requirement for Osteoclastogenesis and Its Increase After Ovariectomy*

1997 • 86 citations

Long-term healing of bone using recombinant human bone morphogenetic protein 2.

1995 • 80 citations

Bone Morphogenetic Protein-12 and -13 Inhibit Terminal Differentiation of Myoblasts, but Do Not Induce Their Differentiation into Osteoblasts

1996 • 66 citations

Effects of Recombinant Human Osteogenic Protein-1 on the Differentiation of Osteoclast-Like Cells and Bone Resorption

1995 • 43 citations

Preparation and Characterization of Polyethylene-Glycol-Modified Salmon Calcitonins

1999 • 38 citations

Perturbation of BMP Signaling in Somitogenesis Resulted in Vertebral and Rib Malformations in the Axial Skeletal Formation

1997 • 34 citations