Sex-dependent regulation of hepatic peroxisome proliferation in mice by trichloroethylene via peroxisome proliferator-activated receptor (PPAR )

Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators

1990 • 3,462 citations

Targeted Disruption of the α Isoform of the Peroxisome Proliferator-Activated Receptor Gene in Mice Results in Abolishment of the Pleiotropic Effects of Peroxisome Proliferators

1995 • 1,626 citations

Fatty Acids, Eicosanoids, and Hypolipidemic Agents Identified as Ligands of Peroxisome Proliferator-Activated Receptors by Coactivator-Dependent Receptor Ligand Assay

1997 • 1,158 citations

Altered Constitutive Expression of Fatty Acid-metabolizing Enzymes in Mice Lacking the Peroxisome Proliferator-activated Receptor α (PPARα)

1998 • 851 citations

VISUALIZATION OF PEROXISOMES (MICROBODIES) AND MITOCHONDRIA WITH DIAMINOBENZIDINE

1969 • 542 citations

Role of PPAR alpha in the mechanism of action of the nongenotoxic carcinogen and peroxisome proliferator Wy-14,643

1997 • 487 citations

Peroxisome proliferator activated receptor-alpha expression in human liver.

1998 • 449 citations

Peroxisome Proliferator Activated Receptor-α Expression in Human Liver

1998 • 397 citations

Novel fatty acid beta-oxidation enzymes in rat liver mitochondria. II. Purification and properties of enoyl-coenzyme A (CoA) hydratase/3-hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase trifunctional protein.

1992 • 337 citations

Mechanistically-based Human Hazard Assessment of Peroxisome Proliferator-induced Hepatocarcinogenesis

1994 • 318 citations

Fatty Acids, Eicosanoids, and Hypolipidemic Agents Identified as Ligands of Peroxisome Proliferator-Activated Receptors by Coactivator-Dependent Receptor Ligand Assay

1997 • 297 citations

Purification and Properties of Acyl-CoA Oxidase from Rat Liver1

1980 • 252 citations

Five of 12 forms of vaccinia virus-expressed human hepatic cytochrome P450 metabolically activate aflatoxin B1.

1990 • 236 citations

Molecular Cloning of cDNA Encoding Rat Very Long-chain Acyl-CoA Synthetase

1996 • 154 citations

Properties of Mitochondrial and Peroxisomal Enoyl-CoA Hydratases from Rat Liver1

1980 • 150 citations

Species differences in response to trichloroethylene

1985 • 144 citations

Species differences in response to trichloroethylene

1985 • 127 citations

Long‐Term Carcinogenicity Bioassays on Trichloroethylene Administered by Inhalation to Sprague‐Dawley Rats and Swiss and B6C3F1 Mice

1988 • 122 citations

Novel metabolites of trichloroethylene through dechlorination reactios in rats, mice and humans

1984 • 122 citations

Peroxisome Proliferator–induced Pleiotropic Responses: Pursuit of a Phenomenon^a

1996 • 111 citations

An overview of peroxisome proliferator-induced hepatocarcinogenesis.

1991 • 106 citations

Clofibrate-inducible rat hepatic P450s IVA1 and IVA3 catalyze the omega- and (omega-1)-hydroxylation of fatty acids and the omega-hydroxylation of prostaglandins E1 and F2 alpha.

1990 • 105 citations

Tissue specificity and species differences in the distribution of urate oxidase in peroxisomes.

1988 • 98 citations

Rat very-long-chain acyl-CoA dehydrogenase, a novel mitochondrial acyl-CoA dehydrogenase gene product, is a rate-limiting enzyme in long-chain fatty acid beta-oxidation system. cDNA and deduced amino acid sequence and distinct specificities of the cDNA-expressed protein.

1994 • 79 citations

Biological potential of basophilic hepatocellular foci and hepatic adenoma induced by the peroxisome proliferator, Wy-14,643

1994 • 79 citations

Cytochrome P450-related differences between rats and mice in the metabolism of benzene, toluene and trichloroethylene in liver microsomes

1993 • 70 citations

Induction of a Novel Long‐Chain Acyl‐CoA Hydrolase in Rat Liver by Administration of Peroxisome Proliferators

1981 • 60 citations

Mutagenic activation of 2-amino-3-methylimidazo[4,5-f]quinoline by complementary DNA-expressed human liver P-450.

1990 • 57 citations

Purification and Properties of Rat D-3-Hydroxyacyl-CoA Dehydratase: D-3-Hydroxyacyl-CoA Dehydratase/D-3-Hydroxyacyl-CoA Dehydrogenase Bifunctional Protein

1996 • 40 citations

Changes in Human & Experimental Toxicology

1994 • 40 citations

Trichloroethylene Induced Cancer in Animals and Its Relevance to Humans

1997 • 5 citations