Stops and starts in mammalian oocytes: recent advances in understanding the regulation of meiotic arrest and oocyte maturation

Regulation of Ovarian Follicular Development in Primates: Facts and Hypotheses

1996 • 1,400 citations

EGF-Like Growth Factors As Mediators of LH Action in the Ovulatory Follicle

2004 • 1,008 citations

THE COMPARATIVE BEHAVIOR OF MAMMALIAN EGGS IN VIVO AND IN VITRO

1935 • 983 citations

Regulation and Role of Adenylyl Cyclase Isoforms

2001 • 666 citations

Oocyte Maturation

1979 • 662 citations

Insights into G Protein Structure, Function, and Regulation

2003 • 639 citations

Gap junctions between the oocyte and companion follicle cells in the mammalian ovary.

1976 • 608 citations

Inhibitory effect of dibutyryl cAMP on mouse oocyte maturation in vitro

1974 • 498 citations

Ovulation: New Dimensions and New Regulators of the Inflammatory-Like Response

2002 • 432 citations

Regulation of mouse oocyte meiotic maturation: Implication of a decrease in oocyte cAMP and protein dephosphorylation in commitment to resume meiosis

1983 • 427 citations

Historical review: A brief history and personal retrospective of seven-transmembrane receptors

2004 • 403 citations

Tissue specificity and physiological relevance of various isoforms of adenylyl cyclase

2000 • 396 citations

Relationship between growth and meiotic maturation of the mouse oocyte

1976 • 393 citations

Chemical structure of sterols that activate oocyte meiosis

1995 • 354 citations

4 Regulation of Oocyte Growth and Maturation in Fish

1995 • 354 citations

Oocyte Maturation Involves Compartmentalization and Opposing Changes of cAMP Levels in Follicular Somatic and Germ Cells: Studies Using Selective Phosphodiesterase Inhibitors

1996 • 350 citations

Role of cyclic nucleotide signaling in oocyte maturation

2002 • 324 citations

The G _s -Linked Receptor GPR3 Maintains Meiotic Arrest in Mammalian Oocytes

2004 • 314 citations

Localization of Luteinizing Hormone Receptor Messenger Ribonucleic Acid Expression in Ovarian Cell Types during Follicle Development and Ovulation*

1991 • 306 citations

Epidermal Growth Factor Family Members: Endogenous Mediators of the Ovulatory Response

2004 • 306 citations

Murine Oocytes Suppress Expression of Luteinizing Hormone Receptor Messenger Ribonucleic Acid by Granulosa Cells1

1997 • 298 citations

Cdc25b phosphatase is required for resumption of meiosis during oocyte maturation

2002 • 295 citations

THE APPEARANCE AND STRUCTURE OF INTERCELLULAR CONNECTIONS DURING THE ONTOGENY OF THE RABBIT OVARIAN FOLLICLE WITH PARTICULAR REFERENCE TO GAP JUNCTIONS

1974 • 283 citations

RGS2 regulates signal transduction in olfactory neurons by attenuating activation of adenylyl cyclase III

2001 • 260 citations

Rat oocyte maturation in vitro : Relief of cyclic AMP inhibition by gonadotropins

1978 • 251 citations

Involvement of cAMP-dependent protein kinase and protein phosphorylation in regulation of mouse oocyte maturation

1986 • 249 citations

Constitutive Activity and Inverse Agonists of G Protein-Coupled Receptors: a Current Perspective: TABLE 1

2003 • 245 citations

Cyclic nucleotide phosphodiesterase 3A–deficient mice as a model of female infertility

2004 • 238 citations

Meiotic Arrest in the Mouse Follicle Maintained by a G _s Protein in the Oocyte

2002 • 232 citations

G protein regulation of adenylate cyclase

1999 • 231 citations

Regulation of G Protein-Coupled Receptor Kinases

2000 • 213 citations

Cholera toxin: A paradigm for multi-functional engagement of cellular mechanisms (Review)

2004 • 205 citations

Activation of the alpha subunit of Gs in intact cells alters its abundance, rate of degradation, and membrane avidity.

1992 • 205 citations

Sphingosine 1-phosphate is a ligand of the human gpr3, gpr6 and gpr12 family of constitutively active G protein-coupled receptors

2002 • 201 citations

Calmodulin-Regulated Adenylyl Cyclases: Cross-Talk and Plasticity in the Central Nervous System

2003 • 201 citations

G ₂ arrest in Xenopus oocytes depends on phosphorylation of cdc25 by protein kinase A

2002 • 198 citations

Regulation of oocyte maturation in the mouse: Possible roles of intercellular communication, cAMP, and testosterone

1983 • 163 citations

Rodent oocytes express an active adenylyl cyclase required for meiotic arrest

2003 • 154 citations

Role of Phosphodiesterase Type 3A in Rat Oocyte Maturation1

2001 • 152 citations

RGS2: a multifunctional regulator of G-protein signaling

2002 • 151 citations

Follicle-Stimulating Hormone Induces a Gap Junction-Dependent Dynamic Change in [cAMP] and Protein Kinase A in Mammalian Oocytes

2002 • 145 citations

Sterol Biosynthesis

1982 • 143 citations

Premature ovarian aging in mice deficient for Gpr3

2005 • 138 citations

Androgens Promote Maturation and Signaling in Mouse Oocytes Independent of Transcription: A Release of Inhibition Model for Mammalian Oocyte Meiosis

2003 • 134 citations

Regulation of Mouse Oocyte Maturation: Effect of Elevating Cumulus Cell cAMP on Oocyte cAMP Levels1

1985 • 133 citations

Recruitment of RGS2 and RGS4 to the Plasma Membrane by G Proteins and Receptors Reflects Functional Interactions

2003 • 133 citations

Direct positive effect of epidermal growth factor on the cytoplasmic maturation of mouse and human oocytes

1991 • 130 citations

Molecular cloning of an orphan G-protein-coupled receptor that constitutively activates adenylate cyclase

1995 • 124 citations

Meiotic resumption and intracellular cAMP levels in mouse oocytes treated with compounds which act on cAMP metabolism

1983 • 123 citations

Epidermal growth factor enhances preimplantation developmental competence of maturing mouse oocytes

1999 • 118 citations

Role of the G-Protein-Coupled Receptor GPR12 as High-Affinity Receptor for Sphingosylphosphorylcholine and Its Expression and Function in Brain Development

2003 • 111 citations

In vitro maturation of mouse oocytes isolated from late, middle, and pre‐antral graafian follicles

1974 • 103 citations

Acquisition of Meiotic Competence in Mouse Oocytes: Absolute Amounts of p34cdc2, Cyclin B1, cdc25C, and wee1 in Meiotically Incompetent and Competent Oocytes1

2000 • 100 citations

Steroids and Oocyte Maturation—A New Look at an Old Story

2003 • 97 citations

Meiosis-activating sterol promotes resumption of meiosis in mouse oocytes cultured in vitro in contrast to related oxysterols [In Process Citation]

1998 • 96 citations

An Accumulation of p34cdc2at the End of Mouse Oocyte Growth Correlates with the Acquisition of Meiotic Competence

1996 • 91 citations

Role of meiosis activating sterols, MAS, in induced oocyte maturation

2002 • 88 citations

Acquisition of Meiotic Competence in Growing Mouse Oocytes Is Controlled at both Translational and Posttranslational Levels

1997 • 87 citations

Resumption of rat oocyte meiosis is paralleled by a decrease in guanosine 3‘,5’-cyclic monophosphate (cGMP) and is inhibited by microinjection of cGMP

1990 • 85 citations

Oocyte maturation in starfish is mediated by the beta gamma-subunit complex of a G-protein.

1993 • 84 citations

Maintenance of meiotic prophase arrest in vertebrate oocytes by a G s protein-mediated pathway

2003 • 84 citations

Novel clusters of receptors for sphingosine‐1‐phosphate, sphingosylphosphorylcholine, and (lyso)‐phosphatidic acid: New receptors for “Old” ligands

2004 • 83 citations

INHIBITION OF DENUDED MOUSE OOCYTE MEIOTI.C MATURATION BY FORSKOLIN, AN ACTIVATOR OF ADENYLATE CYCLASE

1983 • 83 citations

Gap-junctional communication in mouse cumulus-oocyte complexes: implications for the mechanism of meiotic maturation

2002 • 76 citations

Cloning and Characterization of the Cyclic Guanosine Monophosphate-Inhibited Phosphodiesterase PDE3A Expressed in Mouse Oocyte1

2001 • 74 citations

Pertussis toxin inhibits 1-methyladenine-induced maturation in starfish oocytes

1989 • 74 citations

Nuclear and Cytoplasmic Maturation of Mouse Oocytes After Treatment with Synthetic Meiosis-Activating Sterol In Vitro1

1999 • 73 citations

Resumption of oocyte meiosis in mammals: On models, meiosis activating sterols, steroids and EGF-like factors

2005 • 60 citations

A glance at G-protein-coupled receptors for lipid mediators: a growing receptor family with remarkably diverse ligands

2004 • 59 citations

OOCYTIC MEIOSIS IN CULTURED RAT FOLLICLES DURING INHIBITION OF STEROIDOGENESIS

1976 • 57 citations

Meiosis-Activating Sterol Promotes the Metaphase I to Metaphase II Transition and Preimplantation Developmental Competence of Mouse Oocytes Maturing in Vitro1

2004 • 56 citations

Molecular cloning of a novel putative G protein‐coupled receptor (GPCR21) which is expressed predominantly in mouse central nervous system

1993 • 56 citations

Meiosis-Activating Sterol and the Maturation of Isolated Mouse Oocytes1

2001 • 55 citations

Recurring themes in oocyte maturation

1998 • 55 citations

Properties of 1-methyladenine receptors in starfish oocyte membranes: Involvement of pertussis toxin-sensitive GTP-binding protein in the receptor-mediated signal transduction

1992 • 54 citations

The primary structure of the α subunit of a starfish guanosine‐nucleotide‐binding regulatory protein involved in 1‐methyladenine‐induced oocyte maturation

1992 • 52 citations

Calcium elevation in sheep cumulus-oocyte complexes after luteinising hormone stimulation

1998 • 49 citations

cAMP synthesis in the rat oocyte

1983 • 47 citations

Meiosis-Activating Sterol-Mediated Resumption of Meiosis in Mouse Oocytes In Vitro Is Influenced by Protein Synthesis Inhibition and Cholera Toxin1

2000 • 44 citations

Activation of Meiotic Maturation in Rat Oocytes After Treatment with Follicular Fluid Meiosis-Activating Sterol In Vitro and Ex Vivo

2001 • 44 citations

A synthetic analogue of meiosis-activating sterol (FF-MAS) is a potent agonist promoting meiotic maturation and preimplantation development of mouse oocytes maturing in vitro

2004 • 40 citations

A Receptor Linked to a Gi-Family G-Protein Functions in Initiating Oocyte Maturation in Starfish but Not Frogs

2003 • 31 citations

Is meiosis activating sterol (MAS) an obligatory mediator of meiotic resumption in mammals

2002 • 31 citations

Mouse oocyte meiotic resumption and polar body extrusion in vitro are differentially influenced by FSH, epidermal growth factor and meiosis-activating sterol

2004 • 30 citations

Meiosis-activating sterol protects oocytes from precocious chromosome segregation

2003 • 30 citations

Cyclic nucleotide phosphodiesterase 3A–deficient mice as a model of female infertility

2004 • 29 citations

Inhibition of mouse oocyte cyclic AMP phosphodiesterase by steroid hormones: A possible mechanism for steroid hormone inhibition of oocyte maturation

1987 • 27 citations

Analysis of agonist function at fusion proteins between the IP prostanoid receptor and cognate, unnatural and chimaeric G-proteins

1999 • 27 citations

Gonadotropin-Induced Accumulation of 4,4-Dimethylsterols in Mouse Ovaries and Its Temporal Relation to Meiosis1

2001 • 25 citations

Modulation of meiotic arrest in mouse oocytes by guanyl nucleotides and modifiers of G‐proteins

1992 • 14 citations

Long-term agonist stimulation of IP prostanoid receptor depletes the cognate Gsα protein in membrane domains but does not change the receptor level

2004 • 14 citations

Analysis of agonist function at fusion proteins between the IP prostanoid receptor and cognate, unnatural and chimaeric G-proteins

1999 • 12 citations

Recurring themes in oocyte maturation

1998 • 8 citations

Action of hypoxanthine and meiosis-activating sterol on oocyte maturation in the mouse is strain specific

2004 • 6 citations

In Appreciation of Professor R.G.Edwards, Founding Editor of the Human Reproduction Journals

2000 • 4 citations