Endothelin subtype A receptor antagonist induces osteopenia in growing rats

Elevated blood pressure and craniofaclal abnormalities in mice deficient in endothelin-1

1994 • 1,002 citations

Toward a molecular understanding of skeletal development

1995 • 683 citations

Identification of endothelin–1 in the pathophysiology of metastatic adenocarcinoma of the prostate

1995 • 627 citations

Molecular biology and biochemistry of the endothelins

1989 • 620 citations

Molecular characterization of endothelin receptors

1992 • 601 citations

Potentiation of osteoclast bone-resorption activity by inhibition of nitric oxide synthase.

1994 • 246 citations

A specific endothelin subtype A receptor antagonist protects against injury in renal disease progression

1993 • 236 citations

Pharmacological profile of FR139317, a novel, potent endothelin ETA receptor antagonist.

1993 • 217 citations

Role of vascular endothelial cells in bone biology

1994 • 167 citations

Effect of a Specific Endothelin Receptor A Antagonist on mRNA Levels for Extracellular Matrix Components and Growth Factors in Diabetic Glomeruli

1995 • 137 citations

The effects of the endothelin family peptides on cultured osteoblastic cells from rat calvariae

1990 • 131 citations

cGMP produced in response to ANP and CNP regulates proliferation and differentiation of osteoblastic cells

1996 • 122 citations

Endothelin inhibits osteoclastic bone resorption by a direct effect on cell motility: implications for the vascular control of bone resorption.

1992 • 122 citations

Endothelin-1 activates phospholipase C and mobilizes Ca2+ from extra- and intracellular pools in osteoblastic cells

1989 • 84 citations

Role of the endothelial cell in osteoclast control: New perspectives

1993 • 82 citations

Endothelin-1 actions on resorption, collagen and noncollagen protein synthesis, and phosphatidylinositol turnover in bone organ cultures.

1992 • 75 citations

Endothelin modulates osteopontin and osteocalcin messenger ribonucleic acid expression in rat osteoblastic osteosarcoma cells

1993 • 58 citations

Evaluation of urinary pyridinium crosslink excretion as a marker of bone resorption in the rat

1994 • 57 citations

Effect of nitric oxide synthase inhibitors on bone metabolism in growing rats

1996 • 52 citations

Endothelin‐1 localization in bone cells and vascular endothelial cells in rat bone marrow

1993 • 36 citations

Calcium signaling in single rat Leydig cells.

1995 • 34 citations

ETA receptor mediates the signaling of endothelin-1 in osteoblast-like cells

1997 • 34 citations

Endothelin receptors in human parathyroid gland

1992 • 33 citations

Identification and characterization of endothelin receptors on rat osteoblastic osteosarcoma cells: down-regulation by 1,25-dihydroxy-vitamin D3.

1995 • 31 citations

Calcium signaling in endothelin- and platelet-derived growth factor-stimulated chondrocytes

1994 • 27 citations

Interleukin-6 attenuates agonist-mediated calcium mobilization in murine osteoblastic cells.

1994 • 27 citations

Effects of endothelin-1 on Ca2+ signaling and secretion in parathyroid cells

1995 • 20 citations

Endothelin-1 modulates calcium signaling by epidermal growth factor, α-thrombin, and prostaglandin E1 in UMR-106 osteoblastic cells

1993 • 14 citations

Endothelin: Receptors and Transmembrane Signals

1992 • 9 citations