Interleukin-6 attenuates agonist-mediated calcium mobilization in murine osteoblastic cells.

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

Copper-Zinc Superoxide Dismutase (SOD1) Is Released by Microglial Cells and Confers Neuroprotection against 6-OHDA Neurotoxicity

2012 • 8,865 citations

Complementary DNA for a novel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin

1986 • 2,137 citations

Interleukin-6: An Overview

1990 • 1,910 citations

Autocrine generation and requirement of BSF-2/IL-6 for human multiple myelomas

1988 • 1,698 citations

Interferon beta 2/B-cell stimulatory factor type 2 shares identity with monocyte-derived hepatocyte-stimulating factor and regulates the major acute phase protein response in liver cells.

1987 • 1,667 citations

Increased Osteoclast Development After Estrogen Loss: Mediation by Interleukin-6

1992 • 1,437 citations

Interleukin-6 triggers the association of its receptor with a possible signal transducer, gp130

1989 • 1,411 citations

IL-6 is produced by osteoblasts and induces bone resorption.

1990 • 1,121 citations

Cloning and Expression of the Human Interleukin-6 (BSF-2/IFNβ 2) Receptor

1988 • 1,063 citations

Interleukin 6 enhancement of interleukin 3-dependent proliferation of multipotential hemopoietic progenitors.

1987 • 847 citations

Excessive production of interleukin 6/B cell stimulatory factor‐2 in rheumatoid arthritis

1988 • 793 citations

The essential role of B cell stimulatory factor 2 (BSF-2/IL-6) for the terminal differentiation of B cells.

1988 • 791 citations

IL-6-Induced Homodimerization of gp130 and Associated Activation of a Tyrosine Kinase

1993 • 730 citations

Identification of the human 26-kD protein, interferon beta 2 (IFN-beta 2), as a B cell hybridoma/plasmacytoma growth factor induced by interleukin 1 and tumor necrosis factor.

1987 • 690 citations

17 beta-estradiol inhibits interleukin-6 production by bone marrow-derived stromal cells and osteoblasts in vitro: a potential mechanism for the antiosteoporotic effect of estrogens.

1992 • 685 citations

Purification to homogeneity and characterization of human B-cell differentiation factor (BCDF or BSFp-2).

1985 • 679 citations

LIFRβ and gp130 as Heterodimerizing Signal Transducers of the Tripartite CNTF Receptor

1993 • 632 citations

Molecular Regulation of B Lymphocyte Response

1988 • 579 citations

B cell stimulating factor 2/interleukin 6 is a costimulant for human thymocytes and T lymphocytes.

1988 • 537 citations

Inositol trisphosphate formation and calcium mobilization in Swiss 3T3 cells in response to platelet-derived growth factor

1984 • 520 citations

IL-6 stimulates osteoclast-like multinucleated cell formation in long term human marrow cultures by inducing IL-1 release.

1990 • 493 citations

Induction of Neuronal Differentiation in PC12 Cells by B-Cell Stimulatory Factor 2/Interleukin 6

1988 • 402 citations

A Macrophage-Derived Factor Required by Plasmacytomas for Survival and Proliferation in Vitro

1986 • 391 citations

Parathyroid hormone (PTH) and PTH-like protein (PLP) stimulate interleukin-6 production by osteogenic cells: A possible role of interleukin-6 in osteoclastogenesis

1989 • 376 citations

IL-6/BSF-2 functions as a killer helper factor in the in vitro induction of cytotoxic T cells.

1988 • 365 citations

Osteoblasts isolated from mouse calvaria initiate matrix mineralization in culture.

1983 • 363 citations

Interleukin 6. A potential autocrine/paracrine factor in Paget's disease of bone.

1992 • 363 citations

B-cell-stimulatory factor 2 (beta 2 interferon) functions as a second signal for interleukin 2 production by mature murine T cells.

1987 • 357 citations

Receptors for B cell stimulatory factor 2. Quantitation, specificity, distribution, and regulation of their expression.

1987 • 320 citations

Osteoblast-Like Cells in the Presence of Parathyroid Hormone Release Soluble Factor that Stimulates Osteoclastic Bone Resorption*

1986 • 317 citations

Morphological and biochemical characterization of four clonal osteogenic sarcoma cell lines of rat origin.

1983 • 310 citations

Tyrphostins Inhibit Epidermal Growth Factor (EGF)-Receptor Tyrosine Kinase Activity in Living Cells and EGF-Stimulated Cell Proliferation

1989 • 286 citations

Perspectives: Interleukin-6: An osteotropic factor?

1992 • 283 citations

Monocyte-Derived Human B-Cell Growth Factor Identified as Interferon-β ₂ (BSF-2, IL-6)

1988 • 281 citations

Interleukin-6 is produced by bone and modulated by parathyroid hormone

1989 • 237 citations

[31] Use and selectivity of herbimycin A as inhibitor of protein-tyrosine kinases

1991 • 218 citations

Effects of nicotine on cellular function in UMR 106-01 osteoblast-like cells☆

1991 • 204 citations

Multiple biological activities are expressed by a mouse interleukin 6 cDNA clone isolated from bone marrow stromal cells.

1988 • 174 citations

Recombinant human interleukin 6 (B‐cell stimulatory factor 2) is a potent inducer of differentiation of mouse myeloid leukemia cells (M1)

1988 • 166 citations

Relationship of cAMP and calcium messenger systems in prostaglandin-stimulated UMR-106 cells.

1988 • 150 citations

Interleukin-6 inhibits bone formation in vitro

1993 • 136 citations

PTH elevates inositol polyphosphates and diacylglycerol in a rat osteoblast-like cell line

1988 • 121 citations

Interleukin-6 messenger RNA expression and interleukin-6 protein secretion in cells isolated from normal human bone: Regulation by interleukin-1

1991 • 111 citations

Interleukin-6 does not stimulate bone resorption in neonatal mouse calvariae

1991 • 99 citations

Properties of the depolarization-activated calcium and barium entry in osteoblast-like cells

1989 • 96 citations

Herbimycin A, a pp60c-src tyrosine kinase inhibitor, inhibits osteoclastic bone resorption in vitro and hypercalcemia in vivo.

1993 • 91 citations

Endothelin-1 activates phospholipase C and mobilizes Ca2+ from extra- and intracellular pools in osteoblastic cells

1989 • 84 citations

Protein kinase C-activated calcium channel in the osteoblast-like clonal osteosarcoma cell line UMR-106.

1987 • 80 citations

Bone resorption in organ culture: inhibition by the divalent cation ionophores A23187 and X-537A.

1976 • 70 citations

The Effects of Dibutyryl Cyclic AMP, Aminophylline and Propranolol on PTE-Induced Bone Resorptionin Vitro

1974 • 65 citations

Human osteoblastlike cells do not respond to interleukin-6

1991 • 63 citations

92238400 Increased osteoclast development after estrogen loss: Mediation by interleukin-6

1993 • 55 citations

Effects of interleukin-6 on cellular function in UMR-106–01 osteoblastlike cells

1991 • 46 citations

Evidence for receptor-mediated bivalent-cation entry in A10 vascular smooth-muscle cells

1990 • 42 citations

IL 3 and IL 6 do not induce bone resorption in vitro

1990 • 30 citations

PTH (parathyroid hormone) elevates inositol polyphosphates and diacylglycerol in a rat osteoblast-like cell line

1988 • 22 citations

Acute Phosphate Depletion Dissociates Hormonal Stimulated Second Messengers in Osteoblast-Like Cells*

1991 • 21 citations

Prostaglandins enhance parathyroid hormone-evoked increase in free cytosolic calcium concentration in osteoblast-like cells

1991 • 15 citations