Molecular characterization of endothelin receptors

A novel potent vasoconstrictor peptide produced by vascular endothelial cells

1988 • 10,786 citations

Cloning and expression of a cDNA encoding an endothelin receptor

1990 • 2,590 citations

The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes.

1989 • 2,551 citations

Cloning of a cDNA encoding a non-isopeptide-selective subtype of the endothelin receptor

1990 • 2,432 citations

Molecular biology and biochemistry of the endothelins

1989 • 620 citations

Glomerular actions of endothelin in vivo.

1989 • 351 citations

Cloning and expression of human endothelin‐1 receptor cDNA

1991 • 282 citations

Cloning and functional expression of human cDNA for the ETB endothelin receptor

1991 • 273 citations

Rat endothelin is a vasodilator in the isolated perfused mesentery of the rat

1989 • 260 citations

Molecular cloning of a non-isopeptide-selective human endothelin receptor

1991 • 245 citations

Increased plasma level of endothelin-1 and coronary spasm induction in patients with vasospastic angina pectoris.

1991 • 243 citations

cDNA cloning, sequence analysis and tissue distribution of rat preproendothelin-1 mRNA

1991 • 226 citations

Structure-activity relationships of endothelin: Importance of the C-terminal moiety

1988 • 220 citations

An endothelin receptor (ETA) antagonist isolated from Streptomyces misakiensis

1991 • 192 citations

Cl-dependent K transport in a pure population of volume-regulating human erythrocytes

1989 • 187 citations

Two distinct types of endothelin receptors are present on chick cardiac membranes

1989 • 176 citations

Pathophysiological role of endothelin in acute renal failure

1990 • 173 citations

Sarafotoxins S6: Several isotoxins from Atractaspis engaddensis (burrowing asp) venom that affect the heart

1988 • 171 citations

cDNA cloning and chromosomal assignment of the gene encoding endothelin 3

1989 • 167 citations

Heterogeneity of cell surface endothelin receptors.

1990 • 159 citations

[Ala1,3,11,15]endothelin-1 analogs with ETB agonistic activity

1991 • 156 citations

Phosphoramidon, a metalloproteinase inhibitor, suppresses the secretion of endothelin-1 from cultured endothelial cells by inhibiting a big endothelin-1 converting enzyme

1990 • 142 citations

Pituitary site of action of endothelin: Selective inhibition of prolactin release in vitro

1990 • 122 citations

Structure-activity relationship of endothelin: Importance of charged groups

1989 • 120 citations

Two different forms of endothelin receptors in rat lung

1989 • 117 citations

Plasma immunoreactive endothelin-1 in experimental malignant hypertension.

1991 • 107 citations

Cloning and sequence analysis of a cDNA encoding human non-selective type of endothelin receptor

1991 • 104 citations

Specific receptors for endothelin‐3 in cultured bovine endothelial cells and its cellular mechanism of action

1990 • 104 citations

Vascular activities of endothelin‐1 and some alanyl substituted analogues in resistance beds of the rat

1989 • 98 citations

Purification and characterization of bovine lung endothelin receptor.

1991 • 90 citations

Identification of two types of specific endothelin receptors in rat mesangial cell

1989 • 82 citations

Activation of multiple signal transduction pathways by endothelin in cultured human vascular smooth muscle cells

1990 • 77 citations

Stimulation of the hydrolysis of phosphatidylinositol 4,5-bisphosphate and phosphatidylcholine by endothelin, a complete mitogen for Rat-1 fibroblasts

1990 • 68 citations

Specific expression of human endothelin‐2 (ET‐2) gene in a renal adenocarcinoma cell line

1990 • 51 citations

Solubilization and identification of human placental endothelin receptor

1989 • 47 citations

Reoxygenation, But Neither Hypoxia nor Intermittent Ischemia, Increases [125I]Endothelin-1 Binding to Rat Cardiac Membranes

1990 • 30 citations

Bovine Cerebellum Endothelin Receptor: Solubilization and Indentification

1990 • 11 citations