Importins fulfil a dual function as nuclear import receptors and cytoplasmic chaperones for exposed basic domains

The Hsp70 and Hsp60 Chaperone Machines

1998 • 2,793 citations

Transport Between the Cell Nucleus and the Cytoplasm

1999 • 2,001 citations

Sequence requirements for nuclear location of simian virus 40 large-T antigen

1984 • 1,278 citations

NUCLEOCYTOPLASMIC TRANSPORT: The Soluble Phase

1998 • 1,184 citations

Protein import into nuclei: association and dissociation reactions involving transport substrate, transport factors, and nucleoporins

1995 • 767 citations

Ribosome Synthesis in Saccharomyces cerevisiae

1999 • 750 citations

Transport of Proteins and RNAs in and out of the Nucleus

1999 • 741 citations

Isolation of a protein that is essential for the first step of nuclear protein import

1994 • 710 citations

Finding nuclear localization signals

2000 • 690 citations

A Novel Receptor-Mediated Nuclear Protein Import Pathway

1996 • 669 citations

Purification and characterization of CAF-I, a human cell factor required for chromatin assembly during DNA replication in vitro

1989 • 667 citations

Identification of different roles for RanGDP and RanGTP in nuclear protein import.

1996 • 644 citations

Importin beta , transportin, RanBP5 and RanBP7 mediate nuclear import of ribosomal proteins in mammalian cells

1998 • 524 citations

Two different subunits of importin cooperate to recognize nuclear localization signals and bind them to the nuclear envelope

1995 • 511 citations

Trigger factor and DnaK cooperate in folding of newly synthesized proteins

1999 • 491 citations

The human homologue of yeast CRM1 is in a dynamic subcomplex with CAN/Nup214 and a novel nuclear pore component Nup88

1997 • 480 citations

A Novel Class of RanGTP Binding Proteins

1997 • 427 citations

A Distinct Nuclear Import Pathway Used by Ribosomal Proteins

1997 • 335 citations

Sequence and characterization of cytoplasmic nuclear protein import factor p97.

1995 • 274 citations

Nucleocytoplasmic transport enters the atomic age

2001 • 270 citations

A constitutive nucleolar protein identified as a member of the nucleoplasmin family.

1987 • 267 citations

Comparative mutagenesis of nuclear localization signals reveals the importance of neutral and acidic amino acids

1996 • 247 citations

Importin 13: a novel mediator of nuclear import and export

2001 • 240 citations

The importin β/importin 7 heterodimer is a functional nuclear import receptor for histone H1

1999 • 237 citations

Importin-beta-like nuclear transport receptors.

2001 • 218 citations

Roles of molecular chaperones in cytoplasmic protein folding

2000 • 199 citations

RanBP1 stabilizes the interaction of Ran with p97 nuclear protein import.

1996 • 175 citations

Multiple pathways contribute to nuclear import of core histones

2001 • 164 citations

Yrb4p, a yeast Ran-GTP-binding protein involved in import of ribosomal protein L25 into the nucleus

1997 • 163 citations

The nuclear pore‐targeting complex binds to nuclear pores after association with a karyophile

1995 • 163 citations

A Karyophilic Protein Forms a Stable Complex with Cytoplasmic Components Prior to Nuclear Pore Binding

1995 • 144 citations

Nuclear Import of the TATA-binding Protein: Mediation by the Karyopherin Kap114p and a Possible Mechanism for Intranuclear Targeting

1999 • 118 citations

Nuclear chaperones

2000 • 94 citations

Ran-Binding Protein 5 (RanBP5) Is Related to the Nuclear Transport Factor Importin-β but Interacts Differently with RanBP1

1997 • 90 citations

Ribosomes and protein synthesis.

1981 • 87 citations

Nucleoplasmin: the archetypal molecular chaperone.

1990 • 58 citations

Identification of a small, very acidic constitutive nucleolar protein (NO29) as a member of the nucleoplasmin family

1997 • 44 citations

Ribosomes and protein synthesis

1992 • 40 citations

The importin/karyopherin Kap114 mediates the nuclear import of TATA-binding protein

1999 • 39 citations