ATP-Induced Killing of Mycobacteria by Human Macrophages Is Mediated by Purinergic P2Z(P2X7) Receptors

Staurosporine, a potent inhibitor of phospholipidCa++dependent protein kinase

1986 • 2,445 citations

The Cytolytic P _2Z Receptor for Extracellular ATP Identified as a P _2X Receptor (P2X ₇ )

1996 • 1,703 citations

Extracellular ATP: effects, sources and fate

1986 • 1,666 citations

The Cell Biology of Macrophage Activation

1984 • 1,623 citations

Signal transduction via P2-purinergic receptors for extracellular ATP and other nucleotides

1993 • 1,259 citations

Immunity to Intracellular Bacteria

1993 • 1,085 citations

Thapsigargin, a novel molecular probe for studying intracellular calcium release and storage

1989 • 583 citations

Differential Effects of Cytolytic T Cell Subsets on Intracellular Infection

1997 • 526 citations

Vaccination against tuberculosis by DNA injection

1996 • 513 citations

Apoptosis, but not necrosis, of infected monocytes is coupled with killing of intracellular bacillus Calmette-Guérin.

1994 • 512 citations

The Permeabilizing ATP Receptor, P2X7

1997 • 486 citations

Purinergic Modulation of Interleukin-1β Release from Microglial Cells Stimulated with Bacterial Endotoxin

1997 • 477 citations

The P2Z purinoceptor: an intriguing role in immunity, inflammation and cell death

1995 • 378 citations

Oxidized ATP. An irreversible inhibitor of the macrophage purinergic P2Z receptor.

1993 • 350 citations

Oxidized ATP. An irreversible inhibitor of the macrophage purinergic P2Z receptor.

1993 • 318 citations

Molecular basis of chronic granulomatous disease [see comments]

1991 • 290 citations

The purinergic P2Z receptor of human macrophage cells. Characterization and possible physiological role.

1995 • 251 citations

Molecular basis of chronic granulomatous disease [see comments]

1991 • 210 citations

Pathogenesis of Pulmonary Tuberculosis: an Interplay of Tissue-Damaging and Macrophage-Activating Immune Responses-Dual Mechanisms That Control Bacillary Multiplication

2014 • 201 citations

Ecto-ATPase activity in cytolytic T-lymphocytes. Protection from the cytolytic effects of extracellular ATP.

1990 • 198 citations

The isoquinoline derivative KN‐62 a potent antagonist of the P2Z‐receptor of human lymphocytes

1997 • 195 citations

Fas ligation triggers apoptosis in macrophages but not endothelial cells

1994 • 192 citations

Induction of the P2z/P2X7 nucleotide receptor and associated phospholipase D activity by lipopolysaccharide and IFN-gamma in the human THP-1 monocytic cell line.

1996 • 190 citations

N-Nitro-L-arginine and N-Monomethyl-L-arginine Exhibit a Different Pattern of Inactivation Toward the Three Nitric Oxide Synthases

1995 • 178 citations

Triggering of human monocyte activation through CD69, a member of the natural killer cell gene complex family of signal transducing receptors.

1994 • 174 citations

Genetics and Resistance to Tuberculosis

1992 • 139 citations

Perforin, a cytotoxic molecule which mediates cell necrosis, is not required for the early control of mycobacterial infection in mice

1997 • 138 citations

Extracellular ATP as a possible mediator of cell-mediated cytotoxicity

1990 • 120 citations

NITROBLUE-TETRAZOLIUM TESTS

1974 • 116 citations

The ATP4− Receptor-Operated Channel (P2Z Class) of Human Lymphocytes Allows Ba2+ and Ethidium+ Uptake: Inhibition of Fluxes by Suramin

1993 • 115 citations

The Neglected Global Tuberculosis Problem: A Report of the 1992 World Congress on Tuberculosis

1994 • 94 citations

H2O2 induces monocyte apoptosis and reduces viability of Mycobacterium avium-M. intracellulare within cultured human monocytes

1996 • 82 citations

The ATP4− receptor-operated ion channel of human lymphocytes: Inhibition of ion fluxes by amiloride analogs and by extracellular sodium ions

1992 • 81 citations

A prelysosomal compartment sequesters membrane-impermeant fluorescent dyes from the cytoplasmic matrix of J774 macrophages.

1988 • 69 citations

IFN-gamma enhances sensitivity of human macrophages to extracellular ATP-mediated lysis.

1991 • 69 citations

Dissociation of the pore-forming and phospholipase D activities stimulated via P2z purinergic receptors in BAC1.2F5 macrophages. Product inhibition of phospholipase D enzyme activity

1993 • 63 citations

Role of extracellular adenosine triphosphate in the cytotoxic T- lymphocyte-mediated lysis of antigen presenting cells

1995 • 58 citations

Expression of the pore-forming P2Z purinoreceptor in Xenopus oocytes injected with poly(A)+ RNA from murine macrophages.

1993 • 48 citations

Protein Tyrosine Kinases and Phosphatases Control Apoptosis Induced by Extracellular Adenosine 5′-Triphosphate

1996 • 35 citations

Escalating threat from tuberculosis: the third epidemic.

1995 • 34 citations

Human Cellular Immune Responses to Mycobacterium tuberculosis

1996 • 29 citations

Activation of early events of the mitogenic response by a P2Y purinoceptor with covalently bound 3'-O-(4-benzoyl)-benzoyladenosine 5'-triphosphate.

1990 • 26 citations

Lysis of human macrophages by cytolytic CD4+ T cells fails to affect survival of intracellularMycobacterium bovis-bacille Calmette-Guérin (BCG)

1995 • 22 citations

A Novel Ligand Blot Assay Detects Different Hyaluronan-Binding Proteins in Rat Liver Hepatocytes and Sinusoidal Endothelial Cells

1996 • 22 citations

Immune Responses in Animal Models

1996 • 21 citations