Dopamine transporter‐dependent induction of C‐Fos in HEK cells

Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter

1996 • 2,452 citations

Cocaine Receptors on Dopamine Transporters Are Related to Self-Administration of Cocaine

1987 • 2,189 citations

Neurotransmitter Transporters: Recent Progress

1993 • 1,089 citations

Amphetamine and cocaine induce drug-specific activation of the c-fos gene in striosome-matrix compartments and limbic subdivisions of the striatum.

1990 • 958 citations

Induction of immediate-early genes and the control of neurotransmitter-regulated gene expression within the nervous system.

1995 • 685 citations

Activation of in the brain

1996 • 670 citations

ΔFosB: A sustained molecular switch for addiction

2001 • 591 citations

Cloning and Expression of a Cocaine-Sensitive Rat Dopamine Transporter

1991 • 587 citations

Cocaine induces striatal c-fos-immunoreactive proteins via dopaminergic D1 receptors.

1991 • 499 citations

Regulation of immediate early gene expression and AP-1 binding in the rat nucleus accumbens by chronic cocaine.

1992 • 466 citations

Multiple Ionic Conductances of the Human Dopamine Transporter: The Actions of Dopamine and Psychostimulants

1997 • 448 citations

Fos Protein Expression and Cocaine-Seeking Behavior in Rats after Exposure to a Cocaine Self-Administration Environment

2000 • 437 citations

Amphetamine-induced loss of human dopamine transporter activity: An internalization-dependent and cocaine-sensitive mechanism

2000 • 410 citations

Effects of cocaine and related drugs in nonhuman primates. III. Self-administration by squirrel monkeys.

1989 • 389 citations

Dopamine in the nucleus accumbens during cocaine self-administration as studied by in vivo microdialysis

1989 • 386 citations

Membrane Trafficking Regulates the Activity of the Human Dopamine Transporter

1999 • 378 citations

Fos: An immediate‐early transcription factor in neurons

1995 • 373 citations

Regulated Trafficking of the Human Dopamine Transporter

1999 • 357 citations

Amphetamine regulates gene expression in rat striatum via transcription factor CREB

1994 • 356 citations

Amphetamine and cocaine induce drug-specific activation of the c-fos gene in striosome-matrix compartment and limbic subdivisions of the striatum

1990 • 354 citations

Potential brain neuronal targets for amphetamine-, methylphenidate-, and modafinil-induced wakefulness, evidenced by c- fos immunocytochemistry in the cat

1996 • 305 citations

The Parkinsonism-inducing Drug 1-Methyl-4-phenylpyridinium Triggers Intracellular Dopamine Oxidation

2000 • 305 citations

Protein Kinase C-mediated Phosphorylation and Functional Regulation of Dopamine Transporters in Striatal Synaptosomes

1997 • 298 citations

Structural requirements for cocaine congeners to interact with dopamine and serotonin uptake sites in mouse brain and to induce stereotyped behavior

1986 • 289 citations

Oxidative stress-induced apoptosis prevented by trolox

1994 • 266 citations

Inhibition of the uptake of tritiated catecholamines by antidepressant and related agents

1967 • 252 citations

Effects of cocaine and related drugs in nonhuman primates. I. [3H]cocaine binding sites in caudate-putamen.

1989 • 236 citations

Dynamic regulation of NGFI-A (zif268, egr1) gene expression in the striatum

1992 • 213 citations

Genes and addiction

2000 • 208 citations

Pharmacological studies of the regulation of chronic FOS-related antigen induction by cocaine in the striatum and nucleus accumbens.

1995 • 202 citations

Phorbol Esters Increase Dopamine Transporter Phosphorylation and Decrease Transport V_max

1997 • 187 citations

Activation of protein kinase C inhibits uptake, currents and binding associated with the human dopamine transporter expressed in Xenopus oocytes.

1997 • 186 citations

Free radical damage to proteins: The influence of the relative localization of radical generation, antioxidants, and target proteins

1991 • 185 citations

Modification of Dopamine Transporter Function: Effect of Reactive Oxygen Species and Dopamine

1996 • 183 citations

Vitamin E analogue Trolox C. E.s.r. and pulse-radiolysis studies of free-radical reactions.

1988 • 180 citations

Protein kinase-mediated bidirectional trafficking and functional regulation of the human dopamine transporter

1998 • 173 citations

Role of [Ca ²⁺ ] _i in induction of c‐ fos , c‐ jun and c‐ myc mRNA in rat PTE after oxidative stress

1992 • 168 citations

Dopamine‐Induced Apoptosis Is Mediated by Oxidative Stress and Is Enhanced by Cyanide in Differentiated PC12 Cells

2000 • 154 citations

[³H]Threo‐(±)‐Methylphenidate Binding to 3,4‐Dihydroxyphenylethylamine Uptake Sites in Corpus Striatum: Correlation with the Stimulant Properties of Ritalinic Acid Esters

1985 • 153 citations

Effects of cocaine and related drugs in nonhuman primates. II. Stimulant effects on schedule-controlled behavior.

1989 • 149 citations

Phorbol esters alter functions of the expressed dopamine transporter

1994 • 118 citations

Differential patterns of regional c-Fos induction in the rat brain by amphetamine and the novel wakefulness-promoting agent modafinil

1998 • 114 citations

Environmental Novelty Differentially Affects c-fosmRNA Expression Induced by Amphetamine or Cocaine in Subregions of the Bed Nucleus of the Stria Terminalis and Amygdala

2001 • 111 citations

Cloning of dopamine, norepinephrine and serotonin transporters from monkey brain: relevance to cocaine sensitivity

2001 • 109 citations

Neurochemical effects of cocaine following acute and repeated injection

1977 • 107 citations

D1-dopamine receptors activate c-fos expression in the fetal suprachiasmatic nuclei.

1992 • 96 citations

ネコ脳のアンフェタミン,メチルフェニデート,モダフィニルの覚醒作用における標的ニューロンのc‐fos免疫組織化学による検索

1996 • 94 citations

Comparative effects of melatonin, <scp>l</scp>‐deprenyl, Trolox and ascorbate in the suppression of hydroxyl radical formation during dopamine autoxidation in vitro

2000 • 88 citations

Repair of amino acid radicals by a vitamin E analogue

1984 • 76 citations

Comparison of changes in extracellular dopamine concentrations in the nucleus accumbens during intravenous self-administration of cocaine or d-amphetamine

1995 • 73 citations

Acute treatment with antidepressant drugs selectively increases the expression of c-fos in the rat brain.

1995 • 65 citations

Induction of c-fos and zif/268 gene expression in rat striatal neurons, following stimulation of D1-like dopamine receptors, involves protein kinase A and protein kinase C

1995 • 64 citations

Patterns of gene expression and behavior induced by chronic dopamine treatments.

2000 • 56 citations

Effects of cocaine and its oxidative metabolites on mitochondrial respiration and generation of reactive oxygen species

2000 • 56 citations

Cocaine accumulates in dopamine‐rich regions of primate brain after I.V. Administration: Comparison with mazindol distribution

1994 • 51 citations

In vivo vulnerability of dopamine neurons to inhibition of energy metabolism

1997 • 48 citations

MPP+ Increases the Vulnerability to Oxidative Stress Rather Than Directly Mediating Oxidative Damage in Human Neuroblastoma Cells

2000 • 41 citations

Multisubtrate mechanism for the inward transport of dopamine by the human dopamine transporter expressed in HEK cells and its inhibition by cocaine

1999 • 40 citations

Cocaine cytotoxicity in hepatocyte cultures from phenobarbital-induced rats: involvement of reactive oxygen species and expression of antioxidant defense systems

1999 • 34 citations

In vivo measures of monoamines during amphetamine-induced behaviors in rats

1990 • 34 citations

Inhibitory effects of ascorbic acid on dopamine uptake by rat striatal synaptosomes: relationship to lipid peroxidation and oxidation of protein sulfhydryl groups

1998 • 33 citations

Prevention by Ginkgo biloba extract (EGb 761) and trolox C of the decrease in synaptosomal dopamine or serotonin uptake following incubation

1992 • 33 citations

Systemic administration of d-amphetamine induces long-lasting oxidative stress in the rat striatum

2000 • 28 citations

Intra-striatal infusion of d-amphetamine induces hydroxyl radical formation: inhibition by MK-801 pretreatment

2000 • 25 citations

Drug interactions with the dopamine transporter in cryopreserved human caudate.

2001 • 19 citations

Possible Relationship between Changes in [3H]DA Uptake and Autoxidation in Rat Striatal Slices

1998 • 15 citations

The dopamine transporter. The cloned target site of parkinsonism-inducing toxins and of drugs of abuse.

1996 • 14 citations

Nomifensine attenuates d-amphetamine-induced dopamine terminal neurotoxicity in the striatum of rats.

2000 • 8 citations