Cloned copy of the haemagglutinin gene codes for human influenza antigenic determinants in E. coli

Experiments in molecular genetics

1972 • 28,260 citations

A rapid alkaline extraction procedure for screening recombinant plasmid DNA

1979 • 15,511 citations

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3a,6a-diphenylglycoluril

1978 • 4,673 citations

Colony hybridization: a method for the isolation of cloned DNAs that contain a specific gene.

1975 • 3,483 citations

Calcium-dependent bacteriophage DNA infection

1970 • 2,743 citations

Isolation of pure IgG1, IgG2a and IgG2b immunoglobulins from mouse serum using protein A-Sepharose

1978 • 2,726 citations

Structural identification of the antibody-binding sites of Hong Kong influenza haemagglutinin and their involvement in antigenic variation

1981 • 1,603 citations

Mapping of RNA by a modification of the Berk-Sharp procedure: the 5′ termini of 15 S β-globin mRNA precursor and mature 10 S β-globin mRNA have identical map coordinates

1979 • 1,286 citations

Human leukocyte interferon produced by E. coli is biologically active

1980 • 528 citations

Cloning and DNA sequence of double-stranded copies of haemagglutinin genes from H2 and H3 strains elucidates antigenic shift and drift in human influenza virus

1980 • 308 citations

Synthesis of human fibroblast interferon by E. coli

1980 • 240 citations

Improved methods for maximizing expression of a cloned gene: a bacterium that synthesizes rabbit β-globin

1980 • 227 citations

Identification in a recombinant influenza virus of structural proteins derived from both parents

1966 • 195 citations

Immunological screening method to detect specific translation products.

1978 • 160 citations

Expression of the human fibroblast interferon gene in Escherichia coli.

1980 • 130 citations

Cloning of cDNA of major antigen of foot and mouth disease virus and expression in E. coli

1981 • 128 citations

Chicken ovalbumin is synthesized and secreted by Escherichia coli.

1978 • 100 citations

Selection of antigenic mutants of influenza viruses. Isolation and peptide mapping of their hemagglutinating proteins

1968 • 97 citations

Studies on the origin of pandemic influenza

1972 • 87 citations

Influenza antigenic determinants are expressed from haemagglutinin genes cloned in Escherichia coli

1980 • 78 citations

Synthesis of simian virus 40 t antigen in Escherichia coli.

1979 • 65 citations