Intervening sequence of DNA identified in the structural portion of a mouse beta-globin gene.

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

A new method for sequencing DNA.

1977 • 7,941 citations

Colony hybridization: a method for the isolation of cloned DNAs that contain a specific gene.

1975 • 3,483 citations

Spliced segments at the 5′ terminus of adenovirus 2 late mRNA

1977 • 1,301 citations

An amazing sequence arrangement at the 5′ ends of adenovirus 2 messenger RNA

1977 • 1,138 citations

Evidence for somatic rearrangement of immunoglobulin genes coding for variable and constant regions.

1976 • 726 citations

Analysis of Endonuclease R· Eco RI Fragments of DNA from Lambdoid Bacteriophages and Other Viruses by Agarose-Gel Electrophoresis

1974 • 633 citations

Hybridization of RNA to double-stranded DNA: formation of R-loops.

1976 • 443 citations

The primary structure of rabbit β-globin mRNA as determined from cloned DNA

1977 • 428 citations

The molecular basis of antibody formation: a paradox.

1965 • 394 citations

Protein expression in E. coli minicells by recombinant plasmids

1977 • 356 citations

Phage lambda receptor chromosomes for DNA fragments made with restriction endonuclease III of Haemophilus influenzae and restriction endonuclease I of Escherichia coli

1975 • 351 citations

The structural organization of ribosomal DNA in drosophila melanogaster

1977 • 342 citations

Nucleotide sequence of a mutant eukaryotic gene: the yeast tyrosine-inserting ochre suppressor SUP4-o.

1977 • 339 citations

R loop mapping of the 18S and 28S sequences in the long and short repeating units of drosophila melanogaster rDNA

1977 • 305 citations

Isolation of a sequence-specific endonuclease (BamI) from Bacillus amyloliquefaciens H

1975 • 301 citations

Two adenovirus mRNAs have a common 5′ terminal leader sequence encoded at least 10 kb upstream from their main coding regions

1977 • 283 citations

A novel arrangement of the 18S and 28S sequences in a repeating unit of drosophila melanogaster rDNA

1977 • 271 citations

A precursor of globin messenger RNA

1976 • 254 citations

Cloning specific segments of the mammalian genome: bacteriophage lambda containing mouse globin and surrounding gene sequences.

1977 • 229 citations

Mapping of poly(A) sequences in the electron microscope reveals unusual structure of type C oncornavirus RNA molecules

1976 • 218 citations

Sequence arrangement of the rDNA of Drosophila melanogaster

1977 • 214 citations

Globin RNA precursor molecules: Biosynthesis and processing in erythroid cells

1977 • 181 citations

Novel mechanism for RNA maturation: the leader sequences of simian virus 40 mRNA are not transcribed adjacent to the coding sequences.

1977 • 169 citations

The isolation and partial characterization of a new restriction endonuclease from Providencia stuartii.

1976 • 155 citations

Purification of globin messenger RNA from dimethylsulfoxide-induced friend cells and detection of a putative globin messenger RNA precursor

1976 • 127 citations

Loop structures in hybrids of early RNA and the separated strands of adenovirus DNA.

1977 • 126 citations

Cloning of an immunoglobulin variable region gene from mouse embryo.

1977 • 123 citations

Cloning and amplification of α and β mouse globin gene sequences synthesised in vitro

1977 • 99 citations

Digestion of deoxyribonucleic acids from bacteriophage T7, λ, and φ80h with site-specific nucleases from Hemophilus influenzae strain Rc and strain Rd

1974 • 94 citations

Polynucleotide Ligase Activity in Cells Infected with Simian Virus 40, Polyoma Virus, or Vaccinia Virus

1969 • 93 citations

Purification of a putative precursor of globin messenger RNA from mouse nucleated erythroid cells.

1977 • 82 citations

Comparison of the nucleotide sequence of the messenger RNA for the major structural protein of SV40 with the DNA sequence encoding the amino acids of the protein.

1977 • 81 citations

Presence of a putative 15S precursor to β-globin mRNA but not to α-globin mRNA in Friend cells

1977 • 47 citations