Detection and mapping of amplified DNA sequences in breast cancer by comparative genomic hybridization.

Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/ neu Oncogene

1987 • 11,429 citations

Comparative Genomic Hybridization for Molecular Cytogenetic Analysis of Solid Tumors

1992 • 3,344 citations

Amplification of a gene encoding a p53-associated protein in human sarcomas

1992 • 1,959 citations

Molecular themes in oncogenesis

1991 • 1,663 citations

Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53

1992 • 1,358 citations

Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles

1992 • 1,117 citations

Detection of complete and partial chromosome gains and losses by comparative genomic in situ hybridization

1993 • 561 citations

ERBB2 amplification in breast cancer analyzed by fluorescence in situ hybridization.

1992 • 542 citations

Oncogene Amplification in Tumor Cells

1986 • 353 citations

BEK and FLG, two receptors to members of the FGF family, are amplified in subsets of human breast cancers.

1991 • 238 citations

Comparative genomic hybridization: a rapid new method for detecting and mapping DNA amplification in tumors.

1993 • 232 citations

Characterization of chromosomal anomalies in human breast cancer

1990 • 218 citations

Amplification of cellular oncogenes: A predictor of clinical outcome in human cancer

1990 • 203 citations

Chromosome 11q13 abnormalities in human cancer.

1991 • 160 citations

Distinctive chromosomal structures are formed very early in the amplification of CAD genes in Syrian hamster cells

1990 • 136 citations

Whole‐arm t(1;16) and i(1q) as sole anomalies identify gain of 1 q as a primary chromosomal abnormality in breast cancer

1992 • 104 citations

Sporadic amplification of the insulin-like growth factor 1 receptor gene in human breast tumors.

1992 • 84 citations

SAS amplification in soft tissue sarcomas.

1992 • 76 citations

Incidence of double minutes, cytogenetic equivalents of gene amplification, in human carcinoma cells

1984 • 50 citations

Proto‐oncogene amplification and homogeneously staining regions in human breast carcinomas

1990 • 49 citations

Amplification of the proto-oncogenes int-2, c-erbB-2 and c-myc in human breast cancer

1989 • 48 citations

Cytogenetic study of breast cancer: Clinicopathologic significance of homogeneously staining regions in 84 patients

1992 • 30 citations

Second international workshop on human chromosome 17.

1991 • 25 citations